Postbiotics and Dental Caries: A Systematic Review.

Objective: This systematic review aimed to evaluate the current evidence regarding the impact of postbiotics on dental caries, focusing on the effectiveness of postbiotic interventions in caries prevention, mechanisms of action, optimal dosages, and administration protocols.

Methods: A literature search was conducted across PubMed/MEDLINE, Scopus, Web of Science, and the Cochrane Library. Eligible studies included randomized controlled trials, quasi-experimental, observational, and in vitro studies.

Unified resilience model using deep learning for assessing power system performance.

Energy resilience in renewable energy sources dissemination components such as batteries and inverters is crucial for achieving high operational fidelity. Resilience factors play a vital role in determining the performance of power systems, regardless of their operating environment and interruptions. This article introduces a Unified Resilience Model (URM) using Deep Learning (DL) to enhance power system performance.

Building capacity and capability for science diplomacy: challenges in decolonizing the curriculum for Global Health System Leadership.

Education policy is the front and center of contemporary science diplomacy. This is particularly the case in global health where nation-states are being called upon to equip their health workforce with leadership skills and competencies to improve population health and engage in health system development. In the perspective that follows, we argue that successfully meeting such demands requires not only a high-quality education offering but also one that is aware of and engaged with the coloniality underpinning its underlying assumptions.

Mediating effect of intolerance of uncertainty between feeling of unsafety and depression/well-being among a sample of Lebanese adults.

Background: Eastern Mediterranean countries, particularly Lebanon, have seen a significant rise in mental disorders, primarily driven by ongoing economic instability, political unrest, and regional conflicts. These conditions fuel feelings of unsafety, which are linked to lower psychological well-being and increased depressive symptoms. Unsafe circumstances inflate apprehension and uncertainty, leaving individuals unable to foresee a stable, secure tomorrow and often trapped in an anticipatory negative thinking state.

Healthcare research and education: actively constructed research knowledge-a model for online systematic reviews and meta-analyses courses.

Employing a mixed-methods approach, this study: (a) scoped the literature for desirable characteristics of online learning environments; (b) analyzed and compared the available online systematic review and meta-analysis (SR/MA) courses; and (c) proposed an outline for a model online systematic review SR/MA course that is aligned with PRISMA principles, and (d) charted learning outcomes, module contents, interactive elements, feedback and module assessment, and course evaluation of the proposed course. The findings highlight the many distinctive aspects and design of the proposed model course, including its comprehensiveness, alignment with PRISMA principles, self-pace and self-direction, with high interactivity levels, augmented by the expert trainer guidance ('human' factor), and individualized feedback, and its conclusion with the incorporation of the learners in virtual research teams undertaking real SR/MA. The proposed model course integrates principles of problem-based learning, where in addition to the provided resources (interactive assignments and video tutorials), trainees will be actively conducting their own real SR/MA as part of the course, while receiving expert feedback to enhance learning outcomes.

Accuracy of deep learning models in the detection of accessory ostium in coronal cone beam computed tomographic images.

Accessory ostium [AO] is one of the important anatomical variations in the maxillary sinus. AO is often associated with sinus pathology. Radiographic imaging plays a very important role in the detection of AO.

Cost-utility analysis of pharmacogenomics-guided tacrolimus treatment of Slovenian patients undergoing kidney transplantation in the U-PGx PREPARE study.

Tacrolimus (TAC) is one of the most widely prescribed maintenance immunosuppressant drugs in solid organ transplantation. Kidney transplantation is often the preferred treatment for patients with the kidney failure and is complemented with TAC treatment. TAC treatment is often associated with adverse drug events, which can be reduced by pharmacogenomic (PGx)-guided prescription.

Associations of plasma Neurofilament light chain with sarcopenia and physical capacity in patients with Alzheimer's diseases.

Background: Despite the close association of Alzheimer's disease (AD) with muscle decline, the biomarkers of age-related muscle loss, termed sarcopenia, in AD remain elusive.

Objectives: We investigated the plasma neurofilament light (NfL) chain levels as potential biomarkers of sarcopenia in AD patients. DESIGN SETTING, PARTICIPANTS, MEASUREMENTS: We conducted a cross-sectional, observational study on older adults, including controls and patients with AD (n = 38-44/group).

Bacterial synthesis of anisotropic gold nanoparticles.

Pseudomonas aeruginosa was used to synthesize anisotropic gold nanoparticles from the unusually reducible aryldiazonium gold (III) salt of the chemical formula [HOOC-4-CHN≡N]AuCl (abbreviated as DS-AuCl). We investigated the effect of bacterial cell density, temperature, and pH on the AuNP synthesis. The bacterial cell density of 6.

Impact of Silanized Nanographene Oxide Concentrations in Different Primers on Bonding Durability between Resin Cement and Zirconia.

Objectives:  Zirconia (ZrO) has been used in dental restorations due to its increased mechanical properties, biocompatibility, low degree of bacterial adhesion, and acceptable optical properties. One of the major drawbacks of ZrO is its short-term durable bond with resin cement. The objective of this study was to evaluate the effect of different primers embedded with silanized nanographene oxide (SGO) sheets on the wettability of ZrO surface and bond strength durability between resin cement and ZrO.

Correlation of the anatomical variations of pancreatic blood vessels and occurrence of diseases of pancreas.

Objective: Aim: The research aims to confirm or reject the hypothesis on the possible relationship between the influence of changes in pancreatic vascular variations on the mechanisms of occurrence of pancreatic diseases based on the collected scientific literature..

Patients And Methods: Materials and Methods: The bibliosemantic, bibliographic, statistical research methods were used in the research.

Evaluation of chloramphenicol derivative N-phenyl 2, 2 dichloroacetamide anticancer and antibacterial properties.

Aims: This study aimed to develop microparticles of N-phenyl-2,2-dichloroacetamide (PDA), a chloramphenicol derivative with potential antibacterial and anticancer properties, to improve drug release and selectivity while reducing toxicity.

Materials & Methods: PDA microparticles were prepared via spray-drying using L-leucine, Trehalose, and Mannitol. The particles were characterized for size, drug release, antibacterial activity, and cytotoxicity against A549 cancer cells and fibroblasts.

Proceedings of the 29th Annual Congress of the International Liver Transplantation Society.

The 2024 Annual Congress of the International Liver Transplantation Society (ILTS) was from May 1-4th in Houston, Texas, USA, under the theme "Liver Disease and Transplantation: Breaking Barriers and Exploring New Frontiers". In addition to a robust scientific program, the congress also hosted a hands-on cadaveric robotic liver surgery course, a machine perfusion workshop, and a transesophageal echocardiography course. In this report, the ILTS Vanguard and Basic Sciences Committees present a summary of the congress proceedings.

Academic voices on the health and humanitarian crises in Gaza.

Academic publications on human rights violations in Gaza surged after Israel's large-scale destruction following Hamas's 7 October 2023 attack. We analysed the uncoordinated cooperative efforts documented in these works by reviewing publications addressing the health and humanitarian crises in Gaza between October 2023 and April 2024. We present a unified academic voice advocating for recognizing and restoring human rights for the people of Gaza.

Leveraging sentiment analysis of food delivery services reviews using deep learning and word embedding.

Companies that deliver food (food delivery services, or FDS) try to use customer feedback to identify aspects where the customer experience could be improved. Consumer feedback on purchasing and receiving goods online platforms is a crucial tool for learning about a company's performance. Many English-language studies have been conducted on sentiment analysis (SA).

Assessment of the Efficacy and Pulmonary Toxicity of Trastuzumab Deruxtecan in HER2-Positive and HER2-Low Metastatic Breast Cancer in a Tertiary Center in the United Arab Emirates.

Introduction: Trastuzumab deruxtecan (T-DXd) is a HER2-directed antibody-drug conjugate indicated for the treatment of unresectable or metastatic HER2-positive breast cancer in patients who have received a prior anti-HER2-based regimen. T-DXd is also indicated for unresectable or metastatic HER2-low breast cancer, following prior chemotherapy in the metastatic setting or recurrent disease within six months of adjuvant chemotherapy. This study aims to evaluate the efficacy and safety of T-DXd in treating HER2-positive and HER2-low metastatic breast cancer (MBC) patients in a real-world clinical setting.

Crop Wild Relatives (CWRs) in the United Arab Emirates: Resources for Climate Resilience and Their Potential Medicinal Applications.

Global climate change threatens the production, growth, and sustainability of plants. Crop wild relatives (CWRs) offer a practical and sustainable solution to these climatic issues by boosting genetic diversity and crop resilience. Even though CWRs are wild relatives of domesticated plants, they are nevertheless mostly neglected.

Artificial Intelligence in Histopathology.

Artificial intelligence will be revolutionizing the healthcare in near future and is already being integrated in several areas. The utilization of artificial intelligence algorithms to extract quantitative information from full-slide histopathology images has been demonstrated in digital pathology. Artificial intelligence (AI) is anticipated to reduce the workload of pathologists, enhance the impartiality and uniformity of pathology reports, and impact treatment choices through the identification of concealed information within easily accessible data.

Exploring the Role of β-Sitosterol, Genistein, and Emodin in Periodontal Regeneration.

The incidence rate of periodontal diseases is high, which affects the quality of life of patients, and is one of the main causes of adult dentition defects. Periodontal diseases cause the periodontal intraosseous defect. If not treated in time, it can lead to alveolar bone resorption and defect, periodontal attachment loss, teeth loosening, and complete tooth loss.

A Review on the Expanding Role of Dentists in Facial Esthetics.

Dentists' role in facial esthetics is growing, with advancements in cosmetic procedures, such as Botox and dermal fillers. Understanding the range of practitioners and their professional backgrounds is crucial for addressing risks. Data collection and analysis was done to retrieve scholarly papers using databases, such as PubMed and advanced Google search, and analyze.

Analytic study and statistical enforcement of extended beta functions imposed by Mittag-Leffler and Hurwitz-Lerch Zeta functions.

Special Function Theory is used in many mathematical fields to model scientific progress, from theoretical to practical. This helps efficiently analyze the newly expanded Beta class of functions on a complicated domain. We use Mittag-Leffler and Hurwitz Lerch zeta (HLZ) kernels to produce the Beta function using the convolution tool.

Surgical removal of pulmonary flow restrictors in children with congenital heart disease: What the outcomes reveal.

Objective: Pulmonary flow restrictors (PFRs) are interesting devices, but their surgical removal outcomes are poorly understood.

Methods: Retrospective review of clinical data from children with bilateral PFRs who underwent device removal during follow-up surgery.

Results: Thirty-four PFRs were explanted from 17 patients (41.

CARE: towards customized assistive robot-based education.

This study proposes a novel approach to enhancing the learning experience of elementary school students by integrating Artificial Intelligence (AI) and robotics in education, focusing on personalized and adaptive learning. Unlike existing adaptive and intelligent tutoring systems, which primarily rely on digital platforms, our approach employs a personalized tutor robot to interact with students directly, combining cognitive and emotional assessment to deliver tailored educational experiences. This work extends the current research landscape by integrating real-time facial expression analysis, subjective feedback, and performance metrics to classify students into three categories: Proficient Students (Prof.