1 results match your criteria: "Unidad de Neuropediatría. Hospital de Cruces. Baracaldo. Vizcaya. España. cgaraizar@hcru.osakidetsa.net[Affiliation]"
Introduction: Eight new antiepileptic drugs (AED) have been marketed in Spain since 1990 and others will soon follow.
Objective: To review the concepts underlying the development of the new drugs, as well as their indications, efficacy and safety.
Development: Pharmacologic antiepileptic intervention is no longer solely directed towards an anticonvulsant effect, but also to epileptogenic prevention, disease modification and reversal of pharmacoresistance.