Comparative genomic analysis of uropathogenic strains from women with recurrent urinary tract infection.

Introduction: Recurrent urinary tract infections (RUTIs) caused by uropathogenic are costly public health problems impacting patients' quality of life.

Aim: In this work, a comparative genomics analysis of three clinical RUTI strains isolated from bladder biopsy specimens was performed.

Materials And Methods: One hundred seventy-two whole genomes of urinary tract strains were selected from the NCBI database.

Geographical approach analysis of the impact of air pollution on newborn intrauterine growth and cord blood DNA damage in Mexico City.

Background: Few epidemiologic studies have focused on the specific source of ambient air pollution and adverse health effects in early life. Here, we investigated whether air pollutants from different emission sources were associated with decreased birth anthropometry parameters and increased DNA adduct formation in mother-child pairs residing in the Mexico City Metropolitan Area (MCMA).

Methods: This cross-sectional study included 190 pregnant women recruited during their last trimester of pregnancy from two hospitals at MCMA, and a Modeling Emissions Inventory (MEI) to calculate exposure to ambient air pollutants from different emissions sources (area, point, mobile, and natural) for two geographical buffers 250 and 750 m radii around the participants households.

Prevalence, causes, and clinical course of patients with surgical reintervention due to complications during cesarean section.

Objective: The objective of the study is to identify the prevalence, causes, and clinical evolution of patients with surgical reintervention due to complications during cesarean section.

Materials And Methods: The file of the Toco-Surgical Unit of the Gynecological Obstetrics Hospital No. 3 of the National Medical Center "La Raza" Mexican Institute of Social Security was reviewed to know the total number of patients undergoing cesarean section from January to December 2019 and cases with reintervention due to complications during cesarean section were selected.

Endothelial dysfunction in children with chronic kidney disease.

Background And Objective: Cardiovascular disease (CVD) is the main cause of death in children with chronic kidney disease (CKD). Inflammation and endothelial dysfunction (ED) are found in the majority of these patients and are factors associated to CVD. Flow mediated dilatation (FMD) is a surrogate marker validated for evaluating ED.

Complicaciones de la histerectomía total laparoscópica en pacientes de un hospital de alta especialidad.

Objetivo: Describir las complicaciones transoperatorias y posoperatorias en pacientes operadas de histerectomía total laparoscópica.

MÉtodo: Serie de casos del servicio de ginecología de la Unidad Médica de Alta Especialidad Hospital de Gineco-Obstetricia No. 3 del Centro Médico Nacional La Raza, del Instituto Mexicano del Seguro Social, de las pacientes sometidas a histerectomía total laparoscópica de diciembre de 2015 a diciembre de 2018.

Ruptured hepatic hematoma managed with a Sengstaken-Blakemore probe in severe preeclampsia with hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome.

We report the case of a 34-year-old woman with a 32-week pregnancy complicated by recurrent severe preeclampsia, HELLP Class I syndrome, and an intact hepatic hematoma of the right lobe detected by ultrasound. During the cesarean section, the rupture of the hematoma occurred and a gastroesophageal probe of the Sengstaken-Blakemore type was placed to occlude the bleeding cavity and the exit tunnel. The balloons were deflated gradually and the probe was removed on the 10 day without complications.

Reduced mitochondrial DNA copy number is associated with the haplogroup, and some clinical features of breast cancer in Mexican patients.

Mitochondrial DNA (mtDNA) copy number and mitochondrial DNA haplogroups have been associated with different types of cancer, including breast cancer, because they alter cellular energy metabolism. However, whether mtDNA copy number or haplogroups are predictors of oxidative stress-related risks in human breast cancer tissue in Mexican patients remains to be determined. Using quantitative real-time PCR assays and sequencing of the mtDNA hypervariable region, analysis of mtDNA copy numbers in 82 breast cancer tissues (BCT) and matched normal adjacent tissues (NAT) was performed to determine if copy number correlated with clinical features and Amerindian haplogroups (A2, B2, B4, C1 and D1) .

Severity of preeclampsia: data from a high specialty hospital in Mexico City.

IntroducciÓn: La severidad de la preeclampsia puede variar según la población en estudio.

Objetivo: Identificar la frecuencia y el tipo de datos de severidad de la preeclampsia en pacientes atendidas en una unidad médica de alta especialidad de la Ciudad de México.

Material Y MÉtodos: Estudio observacional, retrospectivo y transversal de una serie de 100 pacientes embarazadas con preeclampsia grave atendidas en un hospital de tercer nivel de la Ciudad de México, del 1 de agosto al 31 de diciembre de 2018.

Prenatal exposure to particulate matter and ozone: Bulky DNA adducts, plasma isoprostanes, allele risk variants, and neonate susceptibility in the Mexico City Metropolitan Area.

Mexico City's Metropolitan Area (MCMA) includes Mexico City and 60 municipalities of the neighbor states. Inhabitants are exposed to emissions from over five million vehicles and stationary sources of air pollutants such as particulate matter (PM) and ozone. MCMA PM contains elemental carbon and organic carbon (OC).

Particulate matter-associated micronuclei frequencies in maternal and cord blood lymphocytes.

Studies associate particulate matter (PM) exposure with pulmonary, cardiovascular, and neurologic diseases. Elevated levels of coarse (PM10) and fine (PM2.5) PM have been reported in the Mexico City metropolitan area during the last two decades.

[Epirubicina neoadyuvante con o sin docetaxel secuencial en el tratamiento del cáncer de mama avanzado: evaluación de la respuesta patológica completa y tolerabilidad de la quimioterapia].

Objective: To assess the pathological complete response (pCR) rate after neoadjuvant chemotherapy (NC) with anthracyclines with or without taxanes in management of locally advanced breast cancer (LABC).

Method: Patients with LABC were included. A cohort received four cycles of 5-fluorouracil [FEC] (FEC 500 mg/m, epirubicin 75 mg/m, cyclophosphamide 500 mg/m) every 3 weeks followed by four cycles of docetaxel (D) 75 mg/m as 1 h infusion intravenous every 3 weeks.

[Subtle metabolic alterations in adolescents with obesity and polycystic ovarian syndrome].

Objective: To evaluate the frequency of some subtle metabolic alterations in a group of adolescents with obesity and polycystic ovary syndrome (PCOS).

Materials And Methods: A cross-sectional, comparative study was conducted in a group of adolescents with obesity, and characterized as with or without PCOS according with the Rotterdam Consensus. Medical history, anthropometry, gynecologic pelvic ultrasound (to evaluate ovarian volumes, number of antral follicles and endometrial width), as well as serum glucose, insulin, lipoproteins, interleukin-6, tumor necrosis factor alpha, total testosterone, dehydroepiandrosterone, sexual hormones binding globulin, leptin, adiponectin and insulin-like growth factor 1, the free-androgen index, free and available testosterone, and homeostatic model assessment index were calculated.

[Scheduled hysterectomy vs. urgent hysterectomy in patients with placenta accreta in a high specialty medical unit].

Background: Patients with placenta accreta have a high frequency of complications and death risk.

Objective: The aim of this study was to compare the results of scheduled hysterectomy vs. urgent hysterectomy in patients with placenta accreta in a high specialty medical unit.

[Role of uric acid in preeclampsia-eclampsia].

Uric acid is a terminal metabolite of the degradation of nucleotides, which increases their blood levels in patients with preeclampsia-eclampsia, increasing its synthesis by damage and death of trophoblastic cells in proliferation and decreased urinary excretion due a lower glomerular filtration rate and increased absorption in the proximal tubule. Hyperuricemia (> 4.5 mg/dL) is the first biomarker of the clinical chemistry considered as an early evidence of disease (< or = 20 weeks gestation).

[Perinatal complications in patients with chronic renal failure].

Background: Pregnant patients with chronic renal insufficiency (CRI) have a high risk of perinatal complications and deterioration of renal filtration (RF).

Objective: To report perinatal complications and changes of RF according to disease severity.

Material And Method: Cross-sectional study including 28 pregnant patients grouped into three categories of CRI according to initial creatinine (Cr): mild CRI < 1.

[Maternal complications and HELLP syndrome].

Background: HELLP syndrome is associated with more serious cases of preeclampsia-eclampsia with a high frequency of maternal complications.

Objective: To report the prevalence and type of maternal complications in patients with HELLP syndrome and to compare these with the recent literature.

Patients And Methods: A cross-sectional study was carried out in patients with HELLP syndrome treated between July 1, 2009 and July 31, 2010 in the intensive care unit.

[Perinatal complications in patients with chronic renal insufficiency on hemodialysis].

Background: Pregnant patients with chronic renal insufficiency treated with hemodialysis experience adverse perinatal results.

Objective: To compare perinatal complications of patients with chronic renal insufficiency undergoing hemodialysis who become pregnant vs. the complications of women with chronic renal insufficiency not undergoing dialysis but who then require dialysis during gestation.

[Correlation index amylase-creatinine clearance to endogenous creatinine clearance in severe preeclampsia].

Introduction: Tubular lesion may cause acute renal insufficiency in pregnant patients with severe preeclampsia.

Objective: To describe the correlation between the amylase/creatinine clearance ratio and endogenous creatinine depuration in pregnant patients with severe preeclampsia.

Material And Method: Transversal study (pilot study) twenty eight women with pregnancies of 20 to 40 weeks complicated by severe preeclampsia were studied.

[TNF-alpha, C-reactive protein and serum adiponectin modified in infertile patients with insulin resistance].

Background: Women's reproductive potential is closely related to nutritional status. Some of the molecules that participate in ovarian regulation are produced in the adipose tissue, and therefore their production is associated with adiposity.

Objective: To determine serum leptin, adiponectin, C-reactive protein, interleukin-6, and tumor necrosis factor alpha in infertile women with or without insulin resistance; and to associate these molecules with adiposity.

[Estrogen therapy effect in arterial tension in postmenopausal women].

Introduction: Experimental studies have shown that estrogens prevent deposit of cholesterol in arteries, have effect upon the endothelial function (to prevent contraction of smooth muscle), and enlarge the vascular tone or vasodilatation.

Objective: To determine changes in arterial pressure before and after use of estrogen-therapy.

Material And Methods: A descriptive study was carried out follow-up during 8 weeks in Obstetric and Gynecologic Hospital (No.

[Ultrasonographic characteristics of biliary gallbladder in patients with preeclampsia-eclampsia].

Background: Preeclampsia-eclampsia is a hypertensive disease of pregnancy with systemic complications. Studies regarding ultrasonographic characteristics of biliary gallbladder are limited. We undertook this study to determine the ultrasonographic biliary gallbladder characteristics in patients with preeclampsia-eclampsia.

[Therapeutic assessment of emergency cerclage. Analysis of a cases series].

Background: Cervical incompetence is the incapacity of cervix to retain a pregnancy until term or until feasibility of the fetus. Patients present cervical enlargement without pain or contractions, vaginal strange sensation and membranes protrusion through most minimum degrees of enlargement. The cervical incompetence management can be rest in bed or cerclage.