Niche and interspecific relationship of alligator weed () after a hundred years' invasion in central China.

Alligator weed ( (Mart.) Griseb.) is considered one of the worst invasive weeds in China.

Arthroscopic Autologous Minced Cartilage Implantation of Cartilage Defects in the Knee: A 2-Year Follow-up of 62 Patients.

Background: Symptomatic cartilage defects of the knee joint are frequently diagnosed and can be treated with different available surgical methods. Nevertheless, there is currently no gold standard treatment for all indications. Minced cartilage implantation is increasingly coming into focus as a refined surgical technique.

Simulating microgravity with 60 days of 6 degree head-down tilt bed rest compromises sleep.

Astronauts in space often experience sleep loss. In the AGBRESA (Artificial Gravity Bed Rest) study, we examined 24 participants (mean age ± SD, 33 ± 9 years) during two months of 6 head-down tilt (HDT) bed rest, which is a well-established spaceflight analogue. Polysomnography was recorded during baseline (BDC-9), HDT (nights 1, 8, 30 and 58) and recovery (R, nights 1 and 12).

The impact of multiple agricultural land uses in sustaining earthworm communities in agroecosystems - A global meta-analysis.

The impact of agricultural land use on biodiversity has been extensively examined through efforts to synthesize available data. Nevertheless, there is still a lack of a thorough synthesis describing the earthworm response to agricultural land-use Our meta-analysis compared undisturbed ecosystems (i.e.

Design of an international, phase IV, open-label study of simoctocog alfa in women/girls with hemophilia A undergoing surgery (NuDIMENSION).

Background: Although hemophilia A mainly affects males, carriers (defined as females with hemophilia A, as well as symptomatic or asymptomatic hemophilia A carriers) are at risk of excessive bleeding, particularly during trauma or during surgical procedures. Clinical trials have focused on male patients with severe disease, and data for females are limited. Improved, evidence-based treatment guidelines for management of hemophilia A carriers are required.

Animal-sourced foods improve child nutrition in Africa.

Child undernutrition remains a widespread public health problem in the Global South, especially in Africa. Childhood stunting-meaning linear growth retardation-is a comprehensive and commonly used indicator of chronic child undernutrition and is mostly the result of insufficient nutrient intake, among other factors. Previous research showed that the consumption of animal-sourced foods (ASF), including meat, dairy, eggs, and fish, is associated with lower rates of child stunting, but reliable evidence for Africa is scant.

Opportunities and challenges of plant proteins as functional ingredients for food production.

Consumer interest in meat and dairy alternatives drives demand for plant-based protein ingredients. While soy and gluten dominate the market, there is a trend to explore alternative crops for functional ingredient production. The multitude of ingredients poses challenges for food manufacturers in selecting the right protein.

Advanced Charge Extended Hückel (CEH) Model and a Consistent Adaptive Minimal Basis Set for the Elements = 1-103.

The Charge Extended Hückel (CEH) model, initially introduced for adaptive atomic orbital (AO) basis set construction ( , 159, 164108), has been significantly revised to enhance accuracy and robustness, particularly in challenging electronic situations. This revision includes an extension toward -elements, covering actinoids with their -electrons in the valence space. We present a novel noniterative approximation for the electrostatic contribution to the effective Fock matrix, which substantially improves performance in polar or charged systems.

Data-Independent Acquisition-Parallel Reaction Monitoring Acquisition Reveals Age-Dependent Alterations of the Lysosomal Proteome in a Mouse Model of Metachromatic Leukodystrophy.

For the reproducible analysis of peptides by mass spectrometry-based proteomics, data-independent acquisition (DIA) and parallel/multiple reaction monitoring (PRM/MRM) deliver unrivalled performance with respect to sensitivity and reproducibility. Both approaches, however, come with distinct advantages and shortcomings. While DIA enables unbiased whole proteome analysis, it shows limitations with respect to dynamic range and the quantification of low-abundant proteins.

The Field Automatic Insect Recognition-Device-A Non-Lethal Semi-Automatic Malaise Trap for Insect Biodiversity Monitoring: Proof of Concept.

Field monitoring plays a crucial role in understanding insect dynamics within ecosystems. It facilitates pest distribution assessment, control measure evaluation, and prediction of pest outbreaks. Additionally, it provides important information on bioindicators with which the state of biodiversity and ecological integrity in specific habitats and ecosystems can be accurately assessed.

Notes on (Convolvulaceae) from Ecuador.

Fieldwork, examination of herbarium specimens and photographic images, supported by molecular sequencing have resulted in the re-interpretation of a number of species of L. found in Ecuador and the recognition of four new species. Standl.

Alzheimer's disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway.

Background: Neurodegenerative disorders, including Alzheimer's disease (AD), have been linked to alterations in tryptophan (TRP) metabolism. However, no studies to date have systematically explored changes in the TRP pathway at both transcriptional and epigenetic levels. This study aimed to investigate transcriptomic, DNA methylomic (5mC) and hydroxymethylomic (5hmC) changes within genes involved in the TRP and nicotinamide adenine dinucleotide (NAD) pathways in AD, using three independent cohorts.

Ultrasound-guided high-intensity focused ultrasound for symptomatic uterine fibroids: clinical outcome of two European centers.

Objectives: The aim of this study is to assess the clinical outcome and mid-term efficacy of ultrasound-guided high-intensity focused ultrasound (USgHIFU) as a treatment for symptomatic uterine fibroids at two major European HIFU centers.

Materials And Methods: This bi-center longitudinal clinical study involved the treatment of 100 patients with symptomatic uterine fibroids using USgHIFU (n = 59 in Germany, n = 41 in Bulgaria). Clinical outcomes were evaluated at 6 weeks, 6 months, and 1 year follow-up utilizing the uterine fibroid symptoms-quality of life questionnaire for fibroid-related symptoms and health-related quality of life as well as MRI imaging for determining the fibroid volume.

A fast thermal desorption unit for micro thermal desorption tubes, Part II: Method development and validation for explosives and chemical warfare agent simulants.

A thermal desorption FF-TG-GC/MS method with a cycle time of just 164s including cryofocusing, thermal desorption, analyte separation and system cool down was developed for the analysis of ten explosives and six chemical warfare agent (CWA) simulants. Sampling was carried out both in liquid and gaseous form using micro thermal desorption tubes (μTD-tubes, 1.4mm I.

The role of individual and environmental socio-economic resources for cognitive change in very old age.

Objectives: Very old adults aged 80+ years old belong to the fastest growing population segment in many countries. Nevertheless, this age group is often underrepresented in studies of cognitive aging. The goal of this study was to examine individual and environmental socio-economic resources as correlates of cognitive aging in very old age.

Engrailed-2 and inflammation convergently and independently impinge on cerebellar Purkinje cell differentiation.

Autism spectrum disorders (ASD) have a complex pathogenesis thought to include both genetic and extrinsic factors. Among the latter, inflammation of the developing brain has recently gained growing attention. However, how genetic predisposition and inflammation might converge to precipitate autistic behavior remains elusive.

Context-dependency of the REM sleep behavior disorder screening questionnaire - Clinical utility under scrutiny.

Introduction: The REM Sleep Behavior Disorder (RBD) Screening Questionnaire (RBDSQ) is a widely established screening tool for detecting isolated RBD (iRBD). However, its accuracy may depend on its application context, e.g.

Transient and permanent hydrocephalus following resection of brain metastases located in the posterior fossa: incidence, risk factors and the necessity of perioperative external ventricular drainage placement.

Purpose: Prophylactic insertion of an external ventricular drainage (EVD) prior to the resection of posterior fossa metastases (PFMs) is a common approach to address postoperative transient and permanent hydrocephalus. However, predicting surgery-related hydrocephalus in the preoperative phase continues to be a challenge. This study aims to analyze the incidence, preoperatively collectable risk factors and necessity of perioperative external ventricular drainage placement after posterior fossa metastasis surgery.