1,824 results match your criteria: "Umraniye Training & Research Hospital[Affiliation]"

Background: This study evaluated the long surgical gauze (SurG) technique as a liver retraction method in laparoscopic sleeve gastrectomy (LSG). Traditional methods involve the Nathanson retractor, associated with ischemia and necrosis complications. In addition, these techniques require an additional trocar with an incision that increases postoperative pain.

View Article and Find Full Text PDF

Background: This study aims to evaluate the relationship between the number of visits to a pediatric emergency department due to asthma attacks and air pollutants.

Methods: In this ecological study, all pediatric patients who visited the pediatric emergency department of a tertiary hospital in Istanbul with asthma between January 2016 and December 2023 were included. The effect of air pollution on the number of patient visits was analyzed using a negative binomial regression model.

View Article and Find Full Text PDF

The ability of the prognostic nutritional index to predict short-term mortality in geriatric acute heart failure.

Egypt Heart J

January 2025

Department of Emergency Medicine, Ümraniye Education and Research Hospital, University of Health Sciences, Site Mahallesi, Adıvar Sokak, No 44/15, Ümraniye, İstanbul, Turkey.

Background: Heart failure is a critical cardiovascular condition, necessitating comprehensive treatment approaches and contributing to elevated mortality rates. This study aimed to evaluate the effect of the prognostic nutritional index (PNI) on the prognosis of geriatric patients diagnosed with acute heart failure.

Results: A total of 104 patients were included and evaluated retrospectively in this study; 57.

View Article and Find Full Text PDF

The association between abdominal ultrasound findings and clinical severity in MIS-C children with extracardiac symptoms.

Eur J Pediatr

January 2025

Department of Pediatric Intensive Care Unit, Dr. Behçet Uz Children Disease and Surgery Training and Research Hospital, University of Health Sciences, Izmir, Turkey.

Unlabelled: This study aimed to evaluate pathological findings on abdominal ultrasonography upon admission of children diagnosed with Multisystem Inflammatory Syndrome in Children (MIS-C) that were associated with a more severe disease course and the need for intensive care unit (ICU) admission. This retrospective and observational study was conducted between March 2020 and May 2022. Abdominal ultrasonography findings were evaluated in children diagnosed with MIS-C associated with SARS-CoV-2.

View Article and Find Full Text PDF

Introduction: Therapeutic plasma exchange (TPE) is crucial for saving lives when used appropriately. This study aimed to assess TPE's impact on tumor necrosis factor-like weak inducer of apoptosis (TWEAK) protein and IL-6 levels in critically ill pediatric patients.

Methods: Conducted between May 2022 and December 2022, the study observed pediatric intensive care unit (PICU) patients undergoing TPE, recording demographics, lab results, TWEAK, and IL-6 levels pre- and post-procedure.

View Article and Find Full Text PDF

Just like in other medical specialties, medical malpractice claims arise in pathology as well. Although the exact rate of malpractice related to pathology cannot be clearly stated in Turkey, it is known to occur more frequently during the diagnosis stage, as reported worldwide. This study discusses the measures that should be taken to prevent these claims by comparing cases with alleged malpractice in pathology, evaluated by the Council of Forensic Medicine, with the literature.

View Article and Find Full Text PDF

Purpose: Postoperative fever (POF)/urinary tract infection (UTI) is one of the most unpleasant and undesirable conditions for surgeons after retrograde intrarenal surgery (RIRS). RIRS is not recommended for any patient with a positive urine culture to avoid POF and UTI, but some patients may develop postoperative UTI even if the urine culture is sterile. This study investigated the predictive factors of fever and UTIs after RIRS.

View Article and Find Full Text PDF

Importance: CHEK2 pathogenic and likely pathogenic variants (PVs) are common, and low-risk (LR) variants, p.I157T, p.S428F, and p.

View Article and Find Full Text PDF

This study was aimed to identify the most frequently observed pathogens in uncomplicated urinary tract infections from outpatient urinary isolates obtained across seven different geographical regions in Türkiye and to determine whether the antibiotic resistance rates of these pathogens differ significantly between these regions. The study included patients aged 18 to 65 years who were diagnosed with uncomplicated urinary tract infections and had positive urine cultures from March 2021 to August 2022, across 37 different centers in Türkiye. The participating centers were selected based on their use of the disk diffusion method, in line with the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines, to ensure standardization of urine culture data.

View Article and Find Full Text PDF

Posterior segment findings in a patient with a biallelic pathogenic variant.

Am J Ophthalmol Case Rep

December 2024

Genomic Laboratory, Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Article Synopsis
  • A 25-year-old man diagnosed with retinitis pigmentosa (RP) showed distinct posterior segment abnormalities during examination, including bone spicule pigmentation and retinal atrophy.
  • Findings from advanced imaging techniques like optical coherence tomography (OCT) revealed unique wavy protrusions on the inner retinal surface, leading to non-cystic petaloid maculopathy and changes in choroidal thickness.
  • The patient's condition not only highlighted the retinal involvement linked to a genetic variant but also raised concerns about potential syndromic associations, including a major depressive disorder requiring hospitalization.
View Article and Find Full Text PDF

Highly selective inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6is) have emerged as a standart of care for first- and second-line therapies in combination with endocrine therapy (ET) for HR+/HER2- metastatic breast cancer (MBC) patients. It has been reported that combination therapy is more effective than ET alone and is safe in elderly patients as well as young patients. Nevertheless, elderly and very old patients with HR+/HER2-MBC treated with CDK4/6 inhibitor (CDK4/6i) combinations are relatively underrepresented in randomized controlled trials.

View Article and Find Full Text PDF

Tuberous sclerosis complex (TSC) is a rare genetic disorder characterized by the formation of benign tumors in various organs, particularly in the central nervous system. We aimed to delineate the molecular profile of Turkish individuals diagnosed with TSC by analyzing the TSC1 and TSC2 genes using next-generation sequencing (NGS). Sophia Genetics' Sophia Inherited Disease Panel was used to perform NGS on 22 individuals diagnosed with TSC and to identify pathogenic variants in the TSC1 and TSC2 genes.

View Article and Find Full Text PDF

Objective Breast cancer most commonly metastasizes to axillary lymph nodes via lymphatic drainage. Today, axillary lymph node surgery is at least as important as primary breast surgery. In today's breast surgery, supported by chemotherapy and radiotherapy, current approaches are taken to avoid axillary dissection in appropriate patient groups.

View Article and Find Full Text PDF

This study aims to evaluate the role of <50% stenotic cervical carotid artery plaques in embolic stroke of undetermined source (ESUS), focusing on plaque characteristics in symptomatic versus asymptomatic carotid arteries (contralateral). In this cross-sectional observational study, 81 patients who met the diagnostic criteria for ESUS and underwent were retrospectively analyzed. Carotid plaques causing <50% stenosis were examined, noting features such as plaque thickness, degree of luminal stenosis, irregularity, ulceration, calcification, and hypodensity.

View Article and Find Full Text PDF

Objective: The aim of this study was to identify key parameters of a scoring system to be developed to predict the homozygous M694V genotype in patients clinically diagnosed with familial Mediterranean fever.

Methods: This study was a cross-sectional analysis of 472 pediatric familial Mediterranean fever patients with a homozygous genotype on exon 10, followed at our tertiary pediatric rheumatology clinic between June 2016 and June 2023. The patients were categorized into 2 groups based on their genotypes: group 1 comprised 402 patients (85.

View Article and Find Full Text PDF
Article Synopsis
  • - The study focuses on improving transitional care for adolescents with juvenile idiopathic arthritis (JIA) as they move to adult healthcare systems, suggesting the need for tailored programs in each country.
  • - A Delphi study involving adolescents, parents, and clinicians was conducted to gather expert opinions and identify key components of transitional care, with significant participation in the initial surveys.
  • - While a consensus was reached on essential transitional care issues for JIA patients, further agreement is needed on practical applications of a final checklist to enhance care in Turkey.
View Article and Find Full Text PDF

The Impact of Microenvironment and Dysplasia Types on the Prognosis of Myelodysplastic Syndrome.

Diagnostics (Basel)

December 2024

Hematology Department, Sultan Abdulhamid Han Suam Training and Research Hospital, Health Sciences University, Istanbul 34668, Turkey.

Article Synopsis
  • A thorough analysis of bone marrow aspiration and biopsy can help diagnose and understand the progression of myelodysplastic syndrome (MDS).
  • Key findings indicate that specific features, such as hyperlobulation in megakaryocytes and abnormal localization of immature progenitors, are linked to poorer survival outcomes.
  • The study emphasizes the importance of the bone marrow microenvironment, with microvessel density being a crucial factor in prognosis for MDS patients.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in fibromyalgia (FM) patients to assess changes in the macula and optic disk.
  • A total of 84 individuals were included, with 44 diagnosed with FM and 40 healthy controls, using various OCT/OCTA parameters and questionnaires to compare findings and correlations.
  • Results show significant retinal changes in FM patients, including lower macular thickness and retinal nerve fiber layer measurements, while some vessel density metrics were higher, indicating OCT/OCTA's potential in objectively assessing neuroretinal changes related to FM.
View Article and Find Full Text PDF

Objective: In this study, we examined whether there was a change in the number of children who had been screened by hip ultrasound, the age of first diagnosis, and the number of invasive and conservative treatments applied due to developmental dysplasia of the hip between 2016 and 2022 among refugees who were in "Temporary Protection Status" in Türkiye?

Methods: The records were collected via the e-health database of the Turkish Ministry of Health. Over 1 month old were included in the study.

Results: The number of ultrasonography (USG) that was performed for developmental dysplasia of the hip survey had significantly increased over time.

View Article and Find Full Text PDF

Objective: To investigate whether the timing of bacillus Calmette-Guerin instillation (TTBCG), which plays a key role in treating non-muscle invasive bladder cancer (NMIBC), after transurethral resection of bladder tumor (TURBT) affects oncologic outcomes.

Methods: Patient data obtained from the Urologic Cancer Database-Bladder (UroCaD-B) of Turkish Uro-oncology Association (TUOA) were evaluated. Data from 292 patients from 12 centers with primary T1HG treated with TURBT and maintenance BCG between 2003 and 2023 were retrospectively analyzed.

View Article and Find Full Text PDF

An Examination of the Self-Efficacy and Factors Influencing Foot Care Behaviors in Individuals with Type 2 Diabetes Mellitus.

Int J Low Extrem Wounds

December 2024

Department of Internal Medicine, Umraniye Training and Research Hospital, University of Health Sciences, İstanbul, Turkiye.

The present descriptive study investigates the general and foot-care self-efficacy and the level of foot-care knowledge of 151 participants who presented to the internal medicine ward and diabetes nursing unit of a training and research hospital in Türkiye. The mean Diabetes Management Self-Efficacy Scale score of the participants was 69.0 ± 15.

View Article and Find Full Text PDF
Article Synopsis
  • The study compared the effectiveness of retrograde ureteral stent (RUS) and percutaneous nephrostomy (PCN) in treating patients with acute obstructive pyelonephritis.
  • While both procedures had similar success rates, PCN had significantly shorter operation and fluoroscopy times compared to RUS.
  • Additionally, PCN resulted in fewer complications and a reduced need for intensive care post-surgery, suggesting it may be the more advantageous option for emergency urinary drainage.
View Article and Find Full Text PDF

Objectives: To evaluate the effectiveness of intramedullary nailing combining with iliac or fibular autograft for the treatment of adult forearm nonunions.

Methods: Design: Retrospective case series.

Setting: Two academic trauma referral center.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates the effectiveness and safety of a guideless catheter placement technique for revision surgeries related to external ventricular drainage and ventricular shunt systems in hydrocephalus treatment.
  • The analysis was conducted on 111 patients who underwent these revisions between January 2020 and January 2023, focusing on demographic and clinical data, including complication rates.
  • Results showed that the guideless technique significantly lowered postoperative complications, with only 1.8% experiencing bleeding and 4.5% facing catheter malposition, highlighting its potential benefits in clinical practice.
View Article and Find Full Text PDF

Do we know about dynapenia?

North Clin Istanb

November 2024

Department of Internal Medicine, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.

Article Synopsis
  • Dynapenia is a condition in older adults defined by reduced muscle strength and function, not linked to a specific disease, leading to significant health issues like disability and increased fall risk.
  • Factors like oxidative stress, mitochondrial dysfunction, and chronic inflammation play a role in the development of dynapenia.
  • Diagnosis involves tests for muscle strength, and management requires a comprehensive approach that includes exercise, nutrition, medications, and fall prevention to enhance quality of life.
View Article and Find Full Text PDF