The Effect of Cognitive-Motor Dual Tasks on the Risk of Falls in Female Saudi Students: A Cross-Sectional Study.

Introduction: Dual tasking (DT) requires individuals to carry out two actions simultaneously, comparable to how the brain can perform a cognitive function while the body is in motion, which eventually enhances human balance. This paper aims to examine and compare the impact of DT on the risk of falling (ROF) among Saudi female students.

Methods: A cross-sectional design was used.

Developing and validating a scale to measure perceived barriers to prosthodontics treatments among partially edentulous patients.

Background: People experiencing tooth loss need dental prostheses to preserve the integrity of their oral structures and replace the missing teeth. Patient-related outcome measures (PROMs) for perceived barriers to prosthodontics treatment are scarce in the literature.

Aims: The aim of this study was to develop a comprehensive scale to identify and measure barriers to prosthodontic treatment as perceived by partially edentulous patients.

Retraction: The anti-Alzheimer potential of : an investigation supported by and approaches.

[This retracts the article DOI: 10.1039/D2RA01340A.].

Serum Vitamin D Level Correlates Significantly With Leptin and Tumor Necrosis Factor-Alpha in Overweight Postmenopausal Women With Hypertension.

Background: Association of serum vitamin D (vitD) with leptin (Lep) and tumor necrosis factor-alpha (TNF-α) is not precisely known in overweight hypertensive (OW-HT) postmenopausal (PMP) women. Hence, the present study was carried out to investigate the body mass index (BMI)-based correlation of serum vitD with Lep and TNF-α in OW-HT PMP women.

Methods: Women subjects in their early PMP (n = 346, age: 51 - 60 years) categorized into three groups had main inclusion criteria of specified range of age, BMI and blood pressure (BP).

Impact of frailty and comorbidity on initial response to lung cancer screening invitation and low-dose CT screening uptake: Findings from the Yorkshire Lung Screening Trial.

Background: Low-dose computed tomography screening reduces lung cancer-specific mortality in high-risk individuals. Lung cancer risk factors overlap with comorbid diseases, highlighting the significance of frailty and comorbidities for lung cancer screening (LCS). Here, we describe the prevalence of frailty and comorbidity in those invited for LCS and evaluate their associations with response to telephone risk assessment invitation and subsequent uptake of LCS.

Correction: Rehman et al. Fabrication, In Vitro and In Vivo Assessment of Eucalyptol-Loaded Nanoemulgel as a Novel Paradigm for Wound Healing. 2022, 1971.

In the original publication, there was a mistake in Figure 4 as published [...

Bilosomal Co-Encapsulated Tamoxifen and Propranolol for Potentiated Anti-Breast Cancer Efficacy: In Vitro and In Vivo Investigation.

: Tamoxifen (TAM) is an anti-breast cancer drug suffering from acquired resistance development, prompting cancer relapse. Propranolol (PRO)'s repurposing for cancer therapy has gained interest. This work aimed to investigate combined TAM/PRO therapy for potentiating the anti-breast cancer activity of TAM.

Enhancing the Therapeutic Effect and Bioavailability of Irradiated Silver Nanoparticle-Capped Chitosan-Coated Rosuvastatin Calcium Nanovesicles for the Treatment of Liver Cancer.

Liver cancer is a prevalent form of carcinoma worldwide. A novel chitosan-coated optimized formulation capped with irradiated silver nanoparticles (INops) was fabricated to boost the anti-malignant impact of rosuvastatin calcium (RC). Using a 2-factorial design, eight formulations were produced using the solvent evaporation process.

Ceftazidime-Avibactam Versus Colistin for the Treatment of Multidrug-Resistant Infections: A Multicenter Cohort Study.

To evaluate the real-world evidence of ceftazidime-avibactam (CAZ-AVI) compared to intravenous colistin for the treatment of multidrug-resistant (MDR) infections. This is a multicenter, retrospective cohort study conducted in the period between 2017 and 2023 at five institutions for patients who received either CAZ-AVI or colistin-based regimens for treating MDR infections. Outcomes were compared using multivariate logistic regression analysis.

Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms.

Unlabelled: Hazardous heavy metals, particularly cadmium (Cd), are widely distributed in the environment and cause oxidative stress in various animal and human organs. Clove oil (CLO), a common aromatic spice, has been used as a traditional medication as it has potent anti-inflammatory, antioxidant, and hepatoprotective properties.

Background/objectives: This study aimed to investigate the antioxidant, antiapoptotic, and anti-inflammatory effects of clove oil (CLO) against hepatorenal toxicity induced by cadmium (Cd).

Exploring the Effects of Imidacloprid on Liver Health and the Microbiome in Rats: A Comprehensive Study.

The current study investigates the systemic effects of imidacloprid, one of the most widely used neonicotinoid insecticides, on the liver and gut microbiome of rats in detail. With consideration of recent discussions on the potential harmfulness of imidacloprid to environmental and human health, the aim was to investigate the influence of this compound in the framework of controlled exposure at different dosages, namely, IMI-5, IMI-10, and IMI-30. Histopathological examination showed that liver morphology changed significantly with the dose, including in terms of cellular disorganization and signs of stress, with an alteration in the hepatic architecture.

Thymoquinone as a potent antimicrobial agent against Yersinia enterocolitica: Mechanisms of action and potential food safety applications.

Yersinia enterocolitica (Y. enterocolitica) is a Gram-negative foodborne pathogen associated with potentially fatal diseases. Herein, the antibacterial activity and possible mechanism of thymoquinone (TQ) against Y.

Low-resource MobileBERT for emotion recognition in imbalanced text datasets mitigating challenges with limited resources.

Modern dialogue systems rely on emotion recognition in conversation (ERC) as a core element enabling empathetic and human-like interactions. However, the weak correlation between emotions and semantics poses significant challenges to emotion recognition in dialogue. Semantically similar utterances can express different types of emotions, depending on the context or speaker.

Marginal Gap Distance and Dynamic Fatigue Performance of Esthetic Crowns for Primary Teeth.

Background: The growing demand for esthetic restorative materials highlights the need to evaluate their marginal accuracy and fracture resistance to ensure optimal clinical outcomes for primary molars.

Aim: The aim was to assess the vertical marginal gap distance and fracture resistance of esthetic restorative materials after cyclic loading.

Design: Forty extracted primary molars were randomly divided into four groups: Group I, stainless steel veneered crowns with tooth-colored material; Group II, prefabricated monolithic zirconia crowns; Group III, yttria-partially stabilized zirconia computer-aided design/computer-aided manufacturing (CAD/CAM) crowns; and Group IV, hybrid ceramic CAD/CAM crowns.

Trace Element Speciation and Nutrient Distribution in : Evaluation and Toxic Metal Concentration Across Plant Tissues.

This study investigated the elemental composition of , addressing the gap in comprehensive trace element profiling of this medicinal plant. The research aimed to determine the distribution of macronutrients, micronutrients, and beneficial and potentially toxic elements across different plant parts (seeds, leaves, stems, and roots). Using ICP-OES analysis, two digestion methods were employed to capture both complex and labile elements.

Estimation and Characterization of Dengue Serotypes in Patients Presenting with Dengue Fever at Makkah Hospitals.

Dengue fever is caused by four common serotypes of the dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4). Patients infected with one serotype may develop lifelong serotype-specific protective immunity. However, they remain susceptible to reinfection with the other serotypes, often increasing the risk of severe forms of dengue.

Thymoquinone-loaded Nanosized Ethosomal-based Hydrogels: Their Preparation, Characterization, in Vitro, Ex Vivo, and Antimicrobial Evaluation against Staphylococcus aureus.

Background: Thymoquinone (TQ) is found in the seeds of Nigella sativa. It has immunomodulatory, antibacterial, anti-inflammatory, antioxidant, astringent, antifungal, and antihistaminic properties, making it a highly valuable compound of interest. However, the use of it as a therapeutic drug is highly challenging because of its poor solubility, low bioavailability, and short-term stability.

Impact of 2021 World Health Organization Grading, Peritumoral Edema, and Radiotherapy on the Recurrence of a Grossly Resected Intracranial Meningiomas: A Ten-Year Follow-Up Study.

Background: The significance of histological grading and peritumoral edema (PTE) in predicting intracranial meningioma recurrence among Saudis is often neglected. This study aimed to evaluate the impact of these factors over a 10-year follow-up period.

Methods: A retrospective cohort of 124 patients with intracranial meningioma was analyzed over the period from 2011 to 2021.

Pivotal role of virulence genes in pathogenicity and vaccine development.

One of the most prevalent human infections is (), which affects more than half of the global population. Although infections are widespread, only a minority of individuals develop severe gastroduodenal disorders. The global resistance of to antibiotics has reached concerning levels, significantly impacting the effectiveness of treatment.

The impact of virtual reality on maternal anxiety, satisfaction, and fetal outcomes among pregnant women undergoing non-stress tests: A systematic review and meta-analysis of randomized controlled trials.

We aimed to investigate the impact of virtual reality (VR) on maternal anxiety, satisfaction, and fetal physiological parameters during non-stress test (NST) in pregnant women. We conducted an extensive search across numerous databases to identify eligible studies from inception to April 2024. Researchers included randomized trials that compared VR intervention during NSTs in the third trimester with control groups.

A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment.

Fungi and their natural products, like secondary metabolites, have gained a huge demand in the last decade due to their increasing applications in healthcare, environmental cleanup, and biotechnology-based industries. The fungi produce these secondary metabolites (SMs) during the different phases of their growth, which are categorized into terpenoids, alkaloids, polyketides, and non-ribosomal peptides. These SMs exhibit significant biological activity, which contributes to the formulation of novel pharmaceuticals, biopesticides, and environmental bioremediation agents.

Molecular diversity and genetic potential of new maize inbred lines across varying sowing conditions in arid environment.

Developing high-yielding and resilient maize hybrids is essential to ensure its sustainable production with the ongoing challenges of considerable shifts in global climate. This study aimed to explore genetic diversity among exotic and local maize inbred lines, evaluate their combining ability, understand the genetic mechanisms influencing ear characteristics and grain yield, and identify superior hybrids suited for timely and late sowing conditions. Seven local and exotic maize inbred lines were genotyped using SSR (Simple Sequence Repeat) markers to assess their genetic diversity.

Depression and anxiety in patients with type 2 diabetes in Indonesia and Malaysia: do age, diabetes duration, foot ulcers, and prescribed medication play a role?

Patients with type 2 diabetes mellitus (T2DM) are susceptible to mental health issues, impacting medication adherence and diabetes control. This study aimed to evaluate factors associated with depression and anxiety among T2DM patients in Indonesia and Malaysia. A cross-sectional study was conducted in Indonesia and Malaysia from October 2022 to April 2023 among T2DM patients.

Modeling of lifetime scenarios with non-monotonic failure rates.

The Weibull distribution is an important continuous distribution that is cardinal in reliability analysis and lifetime modeling. On the other hand, it has several limitations for practical applications, such as modeling lifetime scenarios with non-monotonic failure rates. However, accurate modeling of non-monotonic failure rates is essential for achieving more accurate predictions, better risk management, and informed decision-making in various domains where reliability and longevity are critical factors.

Boosting the catalytic efficiency of UGT51 for efficient production of rare ginsenoside Rh2.

Ginsenoside Rh2(S) is well-known for its therapeutic potential against diverse conditions, including some cancers, inflammation, and diabetes. The enzymatic activity of uridine diphosphate glycosyltransferase 51 (UGT51) from Saccharomyces cerevisiae plays a pivotal role in the glycosylation process between UDP-glucose (donor) and protopanaxadiol (acceptor), to form ginsenoside Rh2. However, the catalytic efficiency of the UGT51 has remained a challenging task.