Evaluation of machine learning-based regression techniques for prediction of diabetes levels fluctuations.

Middle-Aged and Elderly people today face a variety of health problems as a result of their modern lifestyle, which includes increased work stress, less physical activity, and altered food habits. Because of Complications arising, diabetes has become one of the most frequent, severe, and fatal illnesses around the world. Therefore, inaccurate measurements of blood glucose levels can seriously damage vital organs.

Development and Psychometric Validation of the Cyber-Self Scale (CSS) in Saudi Arabia.

Background: Measuring adolescents' and youths' perception of their Cyber-Self can enhance the understanding of how digital technology influences identity formation. While psychological literature offers numerous measures of the self, there is a notable lack of studies addressing the measurement of the Cyber-Self. This study aims to evaluate the reliability, factorial- and criterion-related validity, and measurement invariance of the Cyber-Self Scale (CSS) across age and gender among the youth and adolescents in Saudi Arabia.

Effects of population-based screening for atrial fibrillation on quality of life.

Background: Screening for atrial fibrillation is rising and may worsen or improve quality of life.

Methods: We assessed quality of life (EQ-5D-5L) data in 6,004 participants with stroke risk factors randomised to usual care (n=4,503) or implantable loop recorder with anticoagulation upon detection of atrial fibrillation (n=1,501). Five domains (mobility, selfcare, usual activities, pain/discomfort, anxiety/depression) each scored from one to five were calculated into individual index scores (worst=-0.

Dietary supplementation and the role of phytochemicals against the Alzheimer's disease: Focus on polyphenolic compounds.

Alzheimer's disease is a complicated, multifaceted, neurodegenerative illness that places an increasing strain on healthcare systems. Due to increasing malfunction and death of nerve cells, the person suffering from Alzheimer's disease (AD) slowly and steadily loses their memories, cognitive functions and even their personality. Although medications may temporarily enhance memory, there are currently no permanent therapies that can halt or cure this irreversible neurodegenerative process.

Ultrasensitive quantification of neonicotinoid thiamethoxam in environment using MOF-derived CuCoO/3D rGO based electrochemical sensor integrated with optimized neural network.

Accurate quantification of neonicotinoid insecticides is pivotal to ensure environmental safety by examining and mitigating their potential harmful effects on pollinators and aquatic ecosystems. In this scenario, detection of neonicotinoid insecticide, thiamethoxam (TMX), is significant for safeguarding ecological balance and human health. Hence, we developed a highly sensitive electrochemical sensor for detection of TMX in environmental samples, utilizing a novel nanocomposite with superior electrocatalytic properties and integrating an optimized neural network for accurate data analysis.

Pharmacognistic, proximate and phytochemical analysis of stem of Cistanche tubulosa (Schenck) Hook. F.

A medicinal plant is any plant that in one or more of its organs contains substances that can be used by it or their constituent for therapeutic purposes. The present work was done to evaluate pharmacognostic, fluorescence, proximate and phytochemical analysis of ethanolic extracts of Cistanche tubulosa (Orobanchaceae) along with antimicrobial activity. Antimicrobial activity against four bacterial strains S.

Protective roles of herbal teas against the toxicity of Bisphenol A on morphometry of uterus and improving murine reproductive health (incomplete title and amended by the EIC).

The purpose of the current study was to investigate the potential ameliorating murine reproductive effects of herbal tea extracts against bisphenol A-induced (BPA) cytotoxicity. A comparative study was applied among red, green and blue teas in mice groups. Samples were coded as RTE, GTE and BTE groups, respectively.

Ten-Year Implant Survivorship and Performance of Anatomic Total Shoulder Arthroplasty Patients with the Zimmer Biomet Comprehensive® Shoulder System - a Short Stemmed Humeral Implant and Hybrid Glenoid.

Background: Anatomic total shoulder arthroplasty are highly successful procedures for treatment of glenohumeral arthritis to reduce pain, improve range of motion, and overall quality of life. However, the long-term survivorship of the implant systems is less widely documented in the existing literature. The purpose of this study was to establish the long-term patient outcomes and identify factors influencing the postoperative implant survivorship of total anatomic shoulder arthroplasty devices/procedures utilizing the short-stemmed prosthesis and hybrid glenoid components of the Comprehensive Shoulder System (Zimmer Biomet, Warsaw, IN, USA) at an average of ten years.

Effective Targeting of Glutamine Synthetase with Amino Acid Analogs as a Novel Therapeutic Approach in Breast Cancer.

Cancer cells undergo metabolic rewiring to support rapid proliferation and survival in challenging environments. Glutamine is a preferred resource for cancer metabolism, as it provides both carbon and nitrogen for cellular biogenesis. Recent studies suggest the potential anticancer activity of amino acid analogs.

Stress Analysis and Strength Prediction of Carbon Fiber Composite Laminates with Multiple Holes Using Cohesive Zone Models.

Composite materials play a crucial role in various industries, including aerospace, automotive, and shipbuilding. These materials differ from traditional metals due to their high specific strength and low weight, which reduce energy consumption in these industries. The damage behavior of such materials, especially when subjected to stress discontinuities such as central holes, differs significantly from materials without holes.

Prevalence and control of hypertension in COVID-19 positive cases.

Background: The coronavirus disease (COVID-19) is an infectious disease caused by the newly discovered SARS-CoV-2 virus. Patients diagnosed with COVID-19 experience several complications including hypertension or elevated blood pressure which is a serious medical condition that significantly increases the risks of heart, brain, and kidney diseases.

Objectives: To assess the prevalence and control of hypertension in COVID-19 patients.

Bibliometric analysis: A few suggestions (Part Two).

This manuscript serves as a follow-up to our previous work, "bibliometric analysis: a few suggestions," where we highlighted key aspects of bibliometric research and offered recommendations for improving its rigor. In this draft, we expand on those ideas and provide additional suggestions aimed at enhancing the depth and scope of bibliometric analysis. By analyzing a few randomly selected bibliometric studies, we identified common practices and gaps in the field, which informed the inclusion of new recommendations not covered in our earlier paper.

The tumor distance to the main hepatic vessels is a predictor of recurrence-free survival and overall survival in hepatocellular cancer.

Introduction: The impact of the distance of the tumor from the main hepatic vessels (DTV), such as the Glissonean pedicle or hepatic veins, on oncological outcomes for Hepatocellular carcinoma (HCC) patients is relatively understudied. Therefore, the objective of this study was to explore the correlation between DTV and survival in patients with HCC after curative hepatic resection.

Methods: Consecutive patients who underwent curative-intent liver surgery for HCC between April 2018 and May 2023 were identified from a prospective database.

Assessment of lipid peroxidation and total antioxidant capacity in patients with breast cancer.

Aim: Breast cancer (BC), a disease in which abnormal breast cells grow out of control and form tumors, is a prevalent life-threatening disease worldwide. Oxidative stress has been implicated in the development and progression of various cancers, including BC. Assessing lipid peroxidation and overall antioxidant status in BC offers valuable information on disease progression, patient prognosis, and the effectiveness of therapeutic options.

Regulation of INPP5E in Ciliogenesis, Development, and Disease.

Inositol polyphosphate-5-phosphatase E (INPP5E) is a 5-phosphatase critically involved in diverse physiological processes, including embryonic development, neurological function, immune regulation, hemopoietic cell dynamics, and macrophage proliferation, differentiation, and phagocytosis. Mutations in cause Joubert and Meckel-Gruber syndromes in humans; these are characterized by brain malformations, microphthalmia, situs inversus, skeletal abnormalities, and polydactyly. Recent studies have demonstrated the key role of INPP5E in governing intracellular processes like endocytosis, exocytosis, vesicular trafficking, and membrane dynamics.

Fracture resistance and behavior of endodontically treated maxillary premolars with varying ferrule heights and post numbers: A laboratory study.

Purpose: To investigate how varying ferrule heights and the number of glass fiber posts affect fracture resistance and behavior of endodontically treated maxillary first premolars with substantial loss of tooth structure.

Materials And Methods: Twenty-four extracted endodontically treated human maxillary first premolars were divided into three groups (n = 8) based on ferrule height and post number. The groups were as follows: premolars of 2 mm ferrule height that were restored with single posts (control group), premolars of 0.

Quantum-resilient software security: A fuzzy AHP-based assessment framework in the era of quantum computing.

The introduction of quantum computing has transformed the setting of information technology, bringing both unprecedented opportunities and significant challenges. As quantum technologies continue to evolve, addressing their implications for software security has become an essential area of research. This paradigm change provides an unprecedented chance to strengthen software security from the start, presenting a plethora of novel alternatives.

Synergistic design of a graphene oxide-mediated polyaniline/α-FeO ternary heterostructure: advancing photocatalytic degradation and adsorption efficiency.

With the growing threat of organic pollutants in water bodies, there is an urgent need for sustainable and efficient water decontamination methods. This research focused on synthesizing a novel Z-scheme ternary heterostructure composed of graphene oxide (GO)-mediated polyaniline (PANI) with α-FeO and investigated its potential in brilliant green (BrG) and ciprofloxacin (CIP) degradation tests under visible light. The ternary composite demonstrated exceptional photocatalytic activity, with the optimized 10%PANI/GO/α-FeO (10PGF) photocatalyst achieving 99.

Genome-Wide Association Mapping of Macronutrient Mineral Accumulation in Wheat ( L.) Grain.

The focus on increasing wheat ( L.) grain yield at the expense of grain quality and nutrient accumulation can lead to shortages in macronutrient minerals, which are dangerous for human health. This is important, especially in nations where bread wheat is used in most daily dietary regimens.

The Perils of Methanol Exposure: Insights into Toxicity and Clinical Management.

Methanol is a widely used industrial and household alcohol that poses significant health risks upon exposure. Despite its extensive use, methanol poisoning remains a critical public health concern globally, often resulting from accidental or intentional ingestion and outbreaks linked to contaminated beverages. Methanol toxicity stems from its metabolic conversion to formaldehyde and formic acid, leading to severe metabolic acidosis and multiorgan damage, including profound CNS effects and visual impairments.

Repurposing Dapagliflozin for Mitigation of the Kidney Injury Triggered by Cadmium in Rats: Role of Autophagy, Apoptosis, and the SIRT1/Nrf2/HO-1 Pathway.

The antioxidant/antiapoptotic features of dapagliflozin (DPG) have mediated its beneficial actions against several experimental models. However, no studies have been conducted to determine whether DPG mitigates the renal injury triggered by cadmium (Cd). Herein, DPG was studied for its potential to attenuate kidney damage in Cd-intoxicated rats, as well as to unravel the mechanisms involving oxidative events, autophagy, and apoptosis.

Phytochemical Analysis and Multifaceted Biomedical Activities of Extract as Natural Product-Based Therapies.

This study examined the phytochemical profile and biomedical activities of , a halophytic and drought-resistant shrub. HPLC analysis showed gallic acid (1905.1 μg/g), catechin (1984.

Unraveling Genetic Variation and Inheritance Patterns in Newly Developed Maize Hybrids for Improving Late Wilt Disease Resistance and Agronomic Performance Under Artificial Inoculation Conditions.

Late wilt disease caused by the fungal pathogen represents a major threat to maize cultivation in the Mediterranean region. Developing resistant hybrids and high-yielding offers a cost-effective and environmentally sustainable solution to mitigate yield losses. Therefore, this study evaluated genetic variation, combining abilities, and inheritance patterns in newly developed twenty-seven maize hybrids for grain yield and resistance to late wilt disease under artificial inoculation across two growing seasons.

Vitiligo detection capabilities of 1D photonic crystal biosensing design.

This theoretical work focuses on the application of Tamm resonance-based biosensing using a one-dimensional photonic crystal for detecting skin vitiligo, a condition caused by the loss of pigment in the body. This biosensor utilizes the interaction of light with the photonic structure to identify the specific biomarkers associated with vitiligo. The proposed structure is composed of prism/Ag/skin-sample/(GaP/PS)/glass.

Synthesis of Schiff bases based on Chitosan, thermal stability and evaluation of antimicrobial and antitumor activities.

A Schiff base of Chitosan was prepared by condensing of the Chitosan (CS) with six aromatic aldehydes and confirmed by FT-IR, NMR, XRD, TGA, and DSC. XRD results showed the disappeared of peaks at 2θ = 10° for CS and appeared one peaks at around 2θ of 23° for Schiff bases, while TGA was demonstrated that the thermal stability of CS has improved after the modification with the corresponding aldehyde. Also, DSC shows endothermal peak of CS at 100 °C due to the loss of water and second thermal event related to the decomposition of amine units with an exothermic peak at 295 °C, while Schiff bases shows endothermal peak around 70-95 °C which is related to the loss of water for all samples and the second exothermic peak around 260-280 °C is related to the decomposition of the amine group in the polymer units.