2 results match your criteria: "Umm AI-Qura University[Affiliation]"
Unraveling the potential of vitamins C and D as adjuvants in depression treatment with escitalopram in an LPS animal model.
Inflammopharmacology
April 2024
Lincoln Medical School, University of Lincoln, Brayford Pool Campus, Lincoln, LN6 7TS, UK.
Depression is linked with oxidative stress and inflammation, where key players include nitric oxide (NO), nuclear factor erythroid 2-related factor 2 (Nrf2), Brain-Derived Neurotrophic Factor (BDNF), and Heme Oxidase-1 (HO-1). Augmenting the efficacy of antidepressants represents a compelling avenue of exploration. We explored the potential of vitamins C and D as adjuncts to escitalopram (Esc) in a lipopolysaccharide (LPS)-induced depression model focusing on the aforementioned biomarkers.
View Article and Find Full Text PDFBiomarkers of oxidative stress in acute and chronic bronchial asthma.
J Asthma
August 2014
Department of Biochemistry, Faculty of Medicine, Umm AI-Qura University, Abdia, Makkah , K.S.A .
Objective: Oxidative stress plays an important role in inflammatory diseases of the airways, such as bronchial asthma. This study highlights the effects of the imbalance of oxidant/antioxidant parameters and their roles in the severity of asthma, in order to target the deficiency of antioxidants when treating asthmatic patients.
Methods: The study included 45 male and 45 female subjects, aged 18-48 years, with and without asthma.