2 results match your criteria: "Ulm University Ulm University Medical Center Ulm Germany.[Affiliation]"
Testicular large B-cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCL.
Hemasphere
October 2024
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Barcelona Spain.
Article Synopsis
- * A study involving 61 TLBCL patients analyzed their genetic characteristics compared to nodal DLBCL and primary CNS large B-cell lymphomas; findings indicated that TLBCL has fewer copy number changes but more somatic mutations than nodal DLBCL.
- * The results highlight a unique genetic profile for TLBCL, with most cases classified as MCD, indicating genetic diversity, suggesting that this lymphoma type warrants targeted treatment strategies due to its distinct biology.
Article Synopsis
- The understanding of haematological malignancies is advancing thanks to genetic research, culminating in the publication of the 5th Edition of the WHO Classification of Haematolymphoid Tumours in 2022.
- The full version of this classification, known as the "Blue Book," will be available in print in early 2024 and can be accessed online.
- This special issue of Medizinische Genetik explores the genetic changes that are crucial for classifying haematolymphoid neoplasms according to WHO-HAEM5 and their importance for diagnosing different blood cancers.