8 results match your criteria: "Ulanqab Central Hospital[Affiliation]"

Article Synopsis
  • Advanced lung adenocarcinoma (LUAD) patients with EGFR mutations often develop resistance to first-line EGFR-TKIs, highlighting the need for understanding resistance mechanisms and identifying biomarkers for better treatment strategies.
  • A study of 124 stage IV LUAD patients revealed common mutations in genes like TP53 and MYC, but the presence of certain mutations (PIK3C2G, STK11, EPAS1, BTG2) was specifically linked to poor progression-free survival (PFS) in those experiencing primary resistance to treatment.
  • Identifying these genomic variations helps clinicians predict which patients may not respond effectively to EGFR-TKIs and could guide us towards more personalized therapies.
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Background: Food addiction is a chronic psychological disorder resulting from repeated consumption of highly palatable foods, leading to physical and mental harm. It involves individuals who struggle to control their intake of high-energy, high-fat, and high-sugar foods, often experiencing withdrawal reactions and intense cravings that trigger binge eating during stress. Recent research has focused on the impact of food addiction on physical health, nutrition, and mental well-being.

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Hyperandrogenism-insulin resistance-acanthosis nigricans (HAIR-AN) syndrome is a special and rare subtype of polycystic ovarian syndrome. It can lead to hyperandrogenism (HA), insulin resistance (IR), and acanthosis nigricans (AN) accompanied by acne, hirutism, irregular menstruation, and other androgen excess symptoms. A case of pediatric HAIR-AN syndrome with severe AN was admitted to the Department of Endocrinology, China-Japan Friendship Hospital.

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[Investigation on the current situation of the development of intensive care units in Inner Mongolia Autonomous Region in 2022].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue

September 2023

Department of Critical Care Medicine, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, Inner Mongolia Autonomous Region, China.

Objective: To investigate the development present situation of the department of critical care medicine in Inner Mongolia Autonomous Region (hereinafter referred to as Inner Mongolia), in order to promote the standardized and homogeneous development of critical care medicine in Inner Mongolia, and also provide a reference for discipline construction and resource allocation.

Methods: A survey study was conducted in comprehensive intensive care unit (ICU) of tertiary and secondary hospitals in Inner Mongolia by online questionnaire survey and telephone data verification. The questionnaire was based on the Guidelines for the Construction and Management of Intensive Care Units (Trial) (hereinafter referred to as the Guidelines) issued by the National Health Commission in 2009 and the development trend of the discipline.

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Toxoplasma gondii ROP17 promotes autophagy via the Bcl-2-Beclin 1 pathway.

Folia Parasitol (Praha)

June 2021

School of Basic Medicine, Basic Medical Science Center, Shanxi Medical University, Jinzhong, Shanxi, China.

The apicomplexan Toxoplasma gondii (Nicolle et Manceaux, 1908) secretes a group of serine/threonine kinases from rhoptries, which play vital roles in boosting intracellular infection. Toxoplasma gondii rhoptry organelle protein 17 (ROP17) is one of these important kinase proteins. Nevertheless, its function remains unclear.

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Objective: The aim of present study was to assess the predictive value of the admission prognostic nutrition index (PNI), controlling nutritional status (CONUT) associated with delayed cerebral ischemia (DCI), and 3-month neurological outcomes after aneurysmal subarachnoid hemorrhage (aSAH).

Methods: The clinical data from 252 patients with aSAH were retrospectively analyzed. Receiver operating characteristic analysis was performed to assess the predictive ability of the PNI and CONUT score and identify the cutoff point.

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BACKGROUND Lymphocyte-to-monocyte ratio (LMR) is an independent predictive factor of clinical outcome of acute ischemic stroke and cancer, but the predictive effect of LMR in spontaneous intracerebral hemorrhage (ICH) is unknown. Thus, the aim of this study was to explore the impact of peripheral LMR on the neurological deterioration (ND) during the initial week after spontaneous ICH onset, as well as 90-day mortality. MATERIAL AND METHODS The clinical data of 558 consecutive patients with ICH were retrospectively analyzed.

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