44,885 results match your criteria: "Ukraine; Tbilisi State Medical University[Affiliation]"

The current study aims to elicit information regarding the tail risk transmission mechanism between crude oil (CO) and selected clean energy (CE) stock indices across time and during certain economic events. A Time-Varying Parameter Vector Auto-Regressive model (TVP-VAR) paired with the conditional autoregressive value-at-risk (CAViaR) approach was used to investigate data from January 1, 2015 to December 29, 2022. Overall, we show that an increased vulnerability to tail risk and deficits might be linked to dynamic spillover over examined markets.

View Article and Find Full Text PDF

Background: A war has a catastrophic effect on veterans' health. However, there is a knowledge gap about the veterans' rehabilitation system, requirements, and the satisfaction of doctor-organizers. The present study aims to assess the level of satisfaction of the doctor-organizers of health care with the existing rehabilitation system for anti-terrorist operation (ATO) veterans in Ukraine.

View Article and Find Full Text PDF

The formation of a functional tibial stump after combat injuries with extensive tissue damage is sometimes difficult. We describe a case of reconstruction of the tibial stump after a mine-blast injury. In this case, the fibula was completely removed as a result of fracture, and the tibia was amputated at the border of the upper and middle thirds.

View Article and Find Full Text PDF

Background: Electroconvulsive therapy (ECT) is a safe and effective treatment for several major psychiatric conditions, including treatment-resistant depression, mania, and schizophrenia; nevertheless, its use remains controversial. Despite its availability in some European countries, ECT is still rarely used in others. This study aims to investigate the experiences and attitudes of early career psychiatrists (ECPs) across Europe towards ECT and to examine how their exposure to ECT influences their perceptions.

View Article and Find Full Text PDF

Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry.

Eur Heart J

January 2025

Department of Primary Care and Public Health, Imperial Centre for Cardiovascular Disease Prevention, School of Public Health, Imperial College London, White City Campus, 90 Wood Lane, London W12 0BZ, UK.

Background And Aims: Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear.

Methods: Cross-sectional analysis was conducted in 35 540 patients with HeFH across 50 countries, in the EAS FH Studies Collaboration registry. Prevalence of World Health Organization-defined body mass index categories was investigated in adults (n = 29 265) and children/adolescents (n = 6275); and their association with prevalent ASCVD.

View Article and Find Full Text PDF

Direct cardiac reprogramming or transdifferentiation is a relatively new and promising area in regenerative therapy, cardiovascular disease modeling, and drug discovery. Effective reprogramming of fibroblasts is limited by their plasticity, that is, their ability to reprogram, and depends on solving several levels of tasks: inducing cardiomyocyte-like cells and obtaining functionally and metabolically mature cardiomyocytes. Currently, in addition to the use of more classical approaches such as overexpression of exogenous transcription factors, activation of endogenous cardiac transcription factors via controlled nucleases, such as CRISPR, represents another interesting way to obtain cardiomyocytes.

View Article and Find Full Text PDF

Research is ongoing to develop new phosphors capable of emitting light across a broad spectrum, ranging from the ultraviolet (UV) to the infrared region, with potential applications in diverse fields. Using the method of solid-state reactions, a series of LiBaF:Pr phosphors were obtained, and their luminescent properties in the UV-visible range were studied. The photon cascade emission (PCE) phenomenon has been observed under excitation of the 4f5d bands of Pr.

View Article and Find Full Text PDF

Background: Streptomyces roseochromogenes NRRL 3504 produces clorobiocin, an aminocoumarin antibiotic that inhibits DNA replication. No other natural products have been isolated from this bacterium so far, despite the presence of a rich repertoire of specialized metabolite biosynthesis gene clusters (smBGCs) within its genome. Heterologous expression of smBGCs in suitable chassis speeds up the discovery of the natural products hidden behind these sets of genes.

View Article and Find Full Text PDF

Dietary supplementation and the role of phytochemicals against the Alzheimer's disease: Focus on polyphenolic compounds.

J Prev Alzheimers Dis

January 2025

Indian Scientific Education and Technology Foundation, Lucknow, 226002, India. Electronic address:

Article Synopsis
  • Alzheimer's disease (AD) is a complex, progressive neurodegenerative condition that leads to memory loss and cognitive decline, and there are currently no permanent cures to stop its progression.
  • While existing FDA-approved medications only alleviate symptoms temporarily, recent research has shifted focus towards understanding the underlying cellular and molecular mechanisms that contribute to AD, revealing factors like neuroinflammation and oxidative stress.
  • Promising therapeutic approaches are being explored, particularly phytochemicals (e.g., resveratrol, curcumin) that target these mechanisms, potentially offering new treatment possibilities beyond traditional medications.
View Article and Find Full Text PDF

The study aimed to conduct a survey on the occurrence of benzimidazole (BZ) resistance in strongyles by in vitro egg hatch test (EHT) and larval development test (LDT) and to identify the effective indicators of early resistance detection on horse farms with associated risk factors analysis appraisal. In total, 203 horses from 8 farms underwent the fecal sampling of which 77 horses were selected for in vitro testing. Simultaneously, 18 horses were chosen to analyse the results of in vitro tests compared to the in vivo fecal egg count reduction test (FECRT).

View Article and Find Full Text PDF
Article Synopsis
  • Researchers propose a new method for creating multiple shape memory polymers (SMPs) by mixing immiscible polymers under high pressure and shear, rather than traditional blending techniques.
  • This approach allows for nanoscale homogeneity (40-95 nm) in the blends, improving both shape memory and mechanical performance.
  • The study focused on a blend of polypropylene (PP) and polystyrene (PS), demonstrating that the processed blend achieves a strong triple shape memory effect with high shape fixation and recoverability, along with adjustable transition temperatures.
View Article and Find Full Text PDF

Static Zygomatic Guides: Digital ZAGA Concept.

Oral Maxillofac Surg Clin North Am

January 2025

Desert Ridge Oral Surgery Institute, 20950 N Tatum Boulevard #200, Phoenix, AZ 85050, USA; Private Practice of Oral and Maxillofacial Surgery, Phoenix, AZ, USA; Banner University Medical Center, Department of Oral and Maxillofacial Surgery, University of Arizona, Phoenix, AZ, USA.

Guided zygomatic implant placement surgery has emerged as a promising solution for patients with severe maxillary bone loss, offering precise implant placement and predictable outcomes. This article provides a comprehensive review of the current state-of-the-art techniques, advantages, challenges, and future directions in guided zygomatic implant surgery.

View Article and Find Full Text PDF

Absorption spectra of PS in the ultraviolet and infrared region.

Spectrochim Acta A Mol Biomol Spectrosc

January 2025

Institute of Atomic and Molecular Physics, Jilin University, Changchun 130012 China. Electronic address:

The line list is essential for accurately modeling various astrophysical phenomena, such as stellar photospheres and atmospheres of extrasolar planets. This paper introduces a new line database for the PS molecule spanning from the ultraviolet to the infrared regions, covering wavenumbers up to 45000 cm and containing over ten million transitions between 150,458 states with total angular momentum J < 160. Accurate line intensities for rotational, vibrational and electronic transitions are generated by using the general purpose variational code DUO.

View Article and Find Full Text PDF

Introduction: Nutritional care is a cornerstone of cancer treatment, with the potential to significantly improve patient outcomes by addressing malnutrition and enhancing recovery. Despite growing awareness, the integration of evidence-based nutritional strategies into oncology remains inconsistent. Following a 2020 survey that highlighted critical gaps, the NutriOnc Research Group launched targeted initiatives to raise awareness and improve practices.

View Article and Find Full Text PDF

Crystal Plasticity Simulation of Cyclic Behaviors of AZ31B Magnesium Alloys via a Modified Dislocation-Twinning-Detwinning Model.

Materials (Basel)

December 2024

Shanghai Key Laboratory of Mechanics in Energy Engineering, Shanghai Frontier Science Center of Mechanoinformatics, Shanghai Institute of Applied Mathematics and Mechanics, School of Mechanics and Engineering Science, Shanghai University, Shanghai 200072, China.

In this study, a probabilistic model within the dislotwin constitutive framework of DAMASK (the Düsseldorf Advanced Material Simulation Kit) was established to describe the cyclic loading behaviors of AZ31B magnesium alloys. Considering the detwinning procedure within the twinned region, this newly developed dislocation-twinning-detwinning model was employed to accurately simulate stress-strain behaviors of AZ31B magnesium alloys throughout tension-compression-tension (T-C-T) cycle loading. The investigations revealed that the reduction in yield stress during the reverse loading process was attributed to the active operation of twinning and detwinning modes.

View Article and Find Full Text PDF

Resonant and Non-Resonant Impurity States Related to GaAs/AlGaAs Quantum Well Sub-Bands.

Materials (Basel)

December 2024

Centro de Investigación en Ciencias-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Mexico.

The energy positions and wave function shapes of the ground and excited states of impurities, including resonance states, are studied using the expansion of the impurity wave function in basis functions. The structures under study are rectangular GaAs/AlGaAs quantum wells with four different widths. In all cases, the impurity binding energy (relative to the corresponding sub-band) has a maximum at or near the center of the quantum well, decreases as the heterointerface is approached, and apparently has a limit of 0 if the impurity moves deeper into the barrier.

View Article and Find Full Text PDF

Multilateral Use of Dandelion in Folk Medicine of Central-Eastern Europe.

Plants (Basel)

December 2024

Department of Horticulture, Faculty of Biotechnology and Horticulture, University of Agriculture, 31-120 Kraków, Poland.

Background: Dandelion ( sect. , also referred to as F.H.

View Article and Find Full Text PDF

Understanding social relationships in at-risk species held in captivity is vital for their welfare and potential reintroduction. In social species like the Przewalski's horse (), daily time allocation and space use may be influenced by social structure and, in turn, reflect welfare. Here, we identify social relationships, time budgets, and spatial distribution of a group of nine older (aged 6-21 years) male Przewalski's horses living in a non-breeding (bachelor) group.

View Article and Find Full Text PDF

Sr and Cs distribution in Chornobyl forests: 30 years after the nuclear accident.

J Environ Radioact

January 2025

Savannah River Ecology Laboratory, Warnell School of Forestry and Natural Resources, University of Georgia, Aiken, SC, USA.

The primary aim of this study was to quantify patterns in the distribution of Sr and Cs activity in pine (Pinus sylvestris L.: 18 sites) and birch (Betula pendula Roth.: 2 sites) forests within the Chornobyl exclusion zone, 30 years after the Chornobyl nuclear power plant (NPP) accident (1986).

View Article and Find Full Text PDF

There is a widespread perception that China's digital censorship distances its people from the global internet, and the Chinese Communist Party, through state-controlled media, is the main gatekeeper of information about foreign affairs. Our analysis of narratives about the Russo-Ukrainian War circulating on the Chinese social media platform Weibo challenges this view. Comparing narratives on Weibo with 8.

View Article and Find Full Text PDF

Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of -mutated patients, we aimed at characterizing the immunopathology associated with each phenotype. Although defective T and B cell development is common to all phenotypes, patients with hypomorphic variants can generate T and B cells with signatures of immune dysregulation and produce autoantibodies to a broad range of self-antigens, including type I interferons.

View Article and Find Full Text PDF

Psychogenetic Features of Heredity and Pathology.

J Nerv Ment Dis

February 2025

Department of Psychology and Pedagogy, Kyiv International University, Kyiv, Ukraine.

The purpose of this study is to provide an in-depth examination of the complex aspects of hereditary and pathological conditions arising based on psychogenetic factors, in particular, the disclosure of elements that determine the causes of their appearance. The following methods were used in the study: analytical, typological approaches, and generalization. It was found that genetic inheritance plays a significant role in the occurrence of autism spectrum disorders, bipolar disorder, schizophrenia, and other pathologies.

View Article and Find Full Text PDF

Current status and trend of global research on the pharmacological effects of emodin family: bibliometric study and visual analysis.

Naunyn Schmiedebergs Arch Pharmacol

January 2025

Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Emodin, as a natural active ingredient, has shown great application potential in the fields of medicine, food and cosmetics due to its unique pharmacological effects, such as anti-inflammatory, antioxidant, anti-cancer, etc. In recent years, with the development of science and technology and the increase of people's demand for natural medicine, emodin research has been paid more and more attention by the global scientific research community. The bibliometric analysis of emodin and the construction of knowledge map are still blank.

View Article and Find Full Text PDF

Prediction of body weight (BW) using biometric measurements is an important tool especially for animal welfare and automatic phenotyping tools that needs mathematical models. In this study, it was aimed to predict the BW using body length (BL), chest girth (CG) and width of the waist (WW) for rabbits of the maternal form of Hyla NG. The standard rabbit-raising practices were applied for the animals.

View Article and Find Full Text PDF