44,766 results match your criteria: "Ukraine; Tbilisi State Medical University[Affiliation]"

This study delves into the diverse experiences of Ukrainian refugee women in Poland amid the ongoing Russian war, employing a community-based participatory action research approach in collaboration with a Polish foundation aiding Ukrainian war refugees. With the practical aim of formulating recommendations for the third sector assisting refugees, 33 semi-structured interviews ( = 40.29; = 11.

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A 65-year-old patient was admitted to the Institute with complaints of shortness of breath, palpitation, and limb edema. Comorbidities were type 2 diabetes mellitus, gout, obesity. Echo: left ventricular ejection fraction 22%, left ventricular aneurysm (LVA), floating thrombus 5.

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Background: Ribosomal protein S6 kinase 1 (p70S6K1) is a member of the AGC family of serine/threonine kinases which plays a role in various cellular processes, including protein synthesis, cell growth, and survival. Dysregulation of p70S6K1, characterized by its overexpression and/or hyperactivation, has been implicated in numerous human pathologies, particularly in several types of cancer. Therefore, generating active, recombinant p70S6K1 is critical for investigating its role in cancer biology and for developing novel diagnostic or therapeutic approaches.

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This study unveils a novel property of polyaniline by establishing its catalytic activity in heterogeneous hydrogenation with molecular hydrogen. Polyaniline was activated by heat-treating at different temperatures in a hydrogen atmosphere. The sample treated at 300 °C exhibited the highest catalytic activity for ethylene hydrogenation in the gas phase at atmospheric pressure and for p-nitrotoluene or α-methylstyrene hydrogenation in the liquid phase.

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This study aimed to provide an updated evidence of superior hypophyseal artery (SHA) aneurysms management, including their clinical implications, predictive factors for rupture, therapeutic approaches, and post-treatment outcomes. This systematic review and meta-analysis, following PRISMA guidelines, assessed the literature on superior hypophyseal artery aneurysms. Studies were selected based on predefined criteria, focusing on coiling and clipping interventions.

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The paper analyzes the problem of entropy in the moments of transition from a normal economic situation (2015-2019) to the Pandemic period (2020-2021) and the period of Russia's attack on Ukraine (2022-2023). The research in the article is based on the analysis of electricity, oil, coal, and gas prices in 27 countries of the European Union and Norway. The daily data cover the period from January 1, 2015, to March 30, 2023, and were analyzed using two-dimensional sets of electricity and commodity prices.

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Background: Transcatheter aortic valve replacement (TAVR) has significantly advanced the treatment of severe aortic stenosis (AS), particularly in elderly patients who often have coexisting coronary artery disease (CAD). Chronic total occlusion (CTO), a severe form of CAD, may negatively impact outcomes in TAVR patients, though data are limited. This meta-analysis aims to evaluate the impact of CTO on TAVR outcomes.

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Russia's invasion of Ukraine continues to have a devastating effect on the well-being of Ukrainians and their environment. We evaluated a major environmental hazard caused by the war: the potential for groundwater contamination in proximity to the Zaporizhzhia Nuclear Power Plant (NPP). We quantified groundwater vulnerability with the DRASTIC index, which was originally developed by the United States Environmental Protection Agency and has been used at various locations worldwide to assess relative pollution potential.

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The prevalence of willingness to undergo renal transplantation and its potentially associated factors have been documented in multiple prior studies across different regions, yet certain findings are conflicting. The aim of this study was to determine the global prevalence of willingness for renal transplantation and identify its associated factors through meta-analysis methods. Databases such as Scopus, PubMed, and Embase were utilized for the search strategy, covering the period from April to May 2024.

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The effect of conflict on damage to medical facilities in Mariupol, Ukraine: A quasi-experimental study.

PLOS Glob Public Health

January 2025

Epidemiology of Microbial Diseases Department, Yale Humanitarian Research Lab, Yale School of Public Health, New Haven, Connecticut, United States of America.

Medical facilities are civilian objects specially protected by international humanitarian law. Despite the need for systematic documentation of the effects of war on medical facilities for judiciary accountability, current methods for surveilling damage to protected civilian objects during ongoing armed conflict are insufficient. Satellite imagery damage assessment confers significant possibilities for investigating patterns of war.

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Late-onset Systemic Lupus Erythematosus.

Rheumatol Int

January 2025

Department of Rheumatology, Immunology and Internal Medicine, University Hospital in Kraków, Kraków, Poland.

Systemic lupus erythematosus (SLE) is a multisystem autoimmune rheumatic disease (ARD) that results from the dysregulation of multiple innate and adaptive immune pathways. Late-onset SLE (Lo-SLE) is the term used when the disease is first diagnosed after 50-65 years, though the standard age cut-off remains undefined. Defining "late-onset" as lupus with onset after 50 years is more biologically plausible as this roughly corresponds to the age of menopause.

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Gastric cancer in Ukraine: epidemiologic data and its nosological structure between 2003 and 2020.

Prz Gastroenterol

February 2024

Department of Social Medicine, Public Health and Health Care Management, Dnipro State Medical University, Dnipro, Ukraine.

Introduction: Gastric cancer is one of the world's leading causes of death due to oncological diseases. Gastric cancer comprises a diverse group of diseases that includes several oncological units.

Aim: To analyse the nosological structure of epidemiological data related to gastric cancer in Ukraine and compare it with global trends from 2003 to 2020.

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Electrospun Chitosan/Polylactic Acid Nanofibers with Silver Nanoparticles: Structure, Antibacterial, and Cytotoxic Properties.

ACS Appl Bio Mater

January 2025

Department of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.

Electrospinning, a technique for creating fabric materials from polymer solutions, is widely used in various fields, including biomedicine. The unique properties of electrospun fibrous membranes, such as large surface area, compositional versatility, and customizable porous structure, make them ideal for advanced biomedical applications like tissue engineering and wound healing. By considering the high biocompatibility and well-known regenerative potential of polylactic acid (PLA) and chitosan (CH), as well as the versatile antibacterial effect of silver nanoparticles (AgNPs), this study explores the antibacterial efficacy, adhesive properties, and cytotoxicity of electrospun chitosan membranes with a unique nanofibrous structure and varying concentrations of AgNPs.

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Crosstalk between non-coding RNAs and programmed cell death in colorectal cancer: implications for targeted therapy.

Epigenetics Chromatin

January 2025

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran.

Background: Colorectal cancer (CRC) remains one of the most common causes of cancer-related mortality worldwide. Its progression is influenced by complex interactions involving genetic, epigenetic, and environmental factors. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), have been identified as key regulators of gene expression, affecting diverse biological processes, notably programmed cell death (PCD).

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Saturated F2-rings from Alkenes.

Angew Chem Int Ed Engl

January 2025

Enamine Ltd, Organic synthesis for drug discovery, UKRAINE.

A general method to convert simple exocyclic alkenes (no Ar-substituents) into saturated F2-rings has been developed. The reaction involves the IIII-reagent C6F5I(OAc)2 (F5-PIDA). The reaction efficiently works on the mg-, g-, and even multigram scale.

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How do physical environment risks affect financial market systemic risk? We use remoting data to measure physical environment risks and select 26 banks across 12 EU countries. We extend the CoVaR framework with the quantile-mLSTM algorithm, obtaining time-varying CoVaRs. We then use time-varying partial derivatives to calculate the banks' tail risk spillover effects.

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Fabry disease (FD) is a rare disorder resulting from a genetic mutation characterized by the accumulation of sphingolipids in various cells throughout the human body, leading to progressive and irreversible organ damage, particularly in males. Genetically-determined deficiency or reduced activity of the enzyme (alpha - Galactosidase; α-Gal) leads to the accumulation of sphingolipids in the lysosomes of various cell types, including the heart, kidneys, skin, eyes, central nervous system, and digestive system, triggering damage, leading to the failure of vital organs, and resulting in progressive disability and premature death. FD diagnostics currently depend on costly and time-intensive genetic tests and enzymatic analysis, often leading to delayed or inaccurate diagnoses, which contribute to rapid disease progression.

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Immigration of medical personnel from Ukraine to Poland - Context, regulations, and trends.

Health Policy

December 2024

Health Policy and Management Department, Faculty of Health Sciences, Jagiellonian University Medical College, Institute of Public Health, Skawinska 8 Str., Krakow 31-066, Poland. Electronic address:

Background: The migration of healthcare professionals is common phenomenon and shows upwards trends. Poland, which used to be a source country with marginal immigration, has in the past few years received more immigrants due to the simplified access to the labour market for professionals from outside the European Union. We aimed to analyse the immigration of healthcare workforce to Poland with an emphasis on legislative changes regarding the right to practice of medical personnel from outside the EU (mainly from Ukraine).

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Background: The search for early and minimally invasive diagnostic approaches to pancreatic cancer (PC) remains an important issue. One of the most promising directions is to find a sensitive key in the metabolic changes during widespread causes of PC, i.e.

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Anisotropically Epitaxial P-N Heterostructures Actuating Efficient Z-Scheme Photocatalytic Water Splitting.

Small

January 2025

Key Laboratory of Eco-chemical Engineering, International S&T Cooperation Foundation of Eco-chemical Engineering and Green Manufacture, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, P. R. China.

Crafting anisotropically epitaxial p-n heterostructures with Z-scheme charge transmission is a promising avenue toward excellent photocatalytic efficiency, yet the large lattice mismatch and diverse crystal growth habits between components have often arisen as a big challenge to this goal. Here, anisotropically epitaxial p-n heterostructures with 19.8% lattice mismatch are obtained via a dynamics-mediated seeded growth tactic under reaction temperature as low as 60 °C.

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Abdominal aortic aneurysms (AAAs) are a significant vascular pathology in older adults, often asymptomatic but with high mortality upon rupture. Despite advancements in diagnostic imaging and surgical interventions, AAAs remain a public health concern. This research letter analyzed CDC WONDER data on AAA-related deaths (ICD-10 I71.

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Introduction: Thoracic aortic aneurysms (TAA) are a significant health concern, with the true prevalence likely underestimated due to undiagnosed cases. Outcomes in TAA are influenced by factors like age, sex, and comorbidities such as hypertension. This study examines mortality trends and disparities associated with TAA in US adults.

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Purpose Of Review: Medicine and specifically mental health have been affected by emerging technologies advancing mental health treatment while at the same time bringing new challenges and stressors to the battlefield, military systems, and the warfighter.

Recent Findings: This article reviews the evolving positive and negative impacts of technology on combat mental health and treatment. A history of technology and military mental health concerns and services is followed by an overview of present benefits and risks.

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Lipophilicity and acidity/basicity are fundamental physical properties that profoundly affect the compound's pharmacological activity, bioavailability, metabolism, and toxicity. Predicting lipophilicity, measured by (1-octanol-water distribution coefficient logarithm), and acidity/basicity, measured by (negative of acid ionization constant logarithm), is essential for early drug discovery success. However, the limited availability of experimental data and poor accuracy of standard and assessment methods for saturated fluorine-containing derivatives pose a significant challenge to achieving satisfactory results for this compound class.

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