Crystal structure of -poly[bis-(,-di-methyl-hydroxyl-ammonium) [di-μ-bromido-di-bromido-stannate(II)]].

The title compound, {(CHNO)[SnBr]} , is a layered hybrid perovskite crystallizing in the monoclinic space group 2/. The asymmetric unit consists of one HC-O-NH -CH cation (MeHA), one Sn atom located on a twofold rotation axis, and two Br atoms. The Sn atom has a distorted octa-hedral coordination environment formed by the bromido ligands.

Ensemble learning based sustainable approach to rebuilding metal structures prediction.

The effective implementation of the European Green Deal is based on closing cycles by means of reusing products and extending their durability, especially for steel products in the construction industry. The Life Cycle Assessment gives an opportunity to determine the potential impact caused on the environment by building structures and it is used mainly at the early design stage. At the same time, there are significant gaps when it comes to predicting properties of steel products at the last stage of the life cycle of existing buildings in the End of Life Stage (C1-C4) phases and especially D-Benefits and Loads Beyond the System Boundary.

Age-related features of the pattern of oral fluid patients with non-alcoholic fatty liver disease.

In recent years, non-invasive screening methods for diagnosing various human conditions, including those corresponding to biological age, have attracted great interest, one of the sources for non-invasive research of which is oral fluid.

Prevalence and management of hypertension in Turner syndrome: data from the International Turner Syndrome (I-TS) registry.

Introduction: Cardiovascular disease is the commonest cause of death in Turner syndrome (TS) for which, arterial hypertension has a direct influence and is a key modifiable risk factor.

Objective: To investigate the prevalence and patterns of hypertension diagnosis and management in adult patients with TS who are registered in a large international multicentre database (TS-HTN study).

Methods: Retrospective multi-centre observational study of patients aged ≥18 years, included in the I-TS (International-TS) registry (2020-2022) utilising registry and participating centre collected data.

Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma.

Deletion of the long q arm of chromosome 22 (22qDEL) is the most frequently identified recurrent somatic copy number alteration (SCNA) observed in papillary thyroid carcinoma (PTC). Since its role in PTC is not fully understood, we conducted a pooled analysis of genomic characteristics and clinical correlates in 1094 primary tumors from four published PTC genomic studies. The majority of PTC with 22qDEL exhibited arm-level loss of heterozygosity (86%); nearly all PTC with 22qDEL had losses in 22q12 and 13, which together constitute 70% of the q arm.

Fulvestrant Versus Anastrozole in Endocrine Therapy-Naïve Women With Hormone Receptor-Positive Advanced Breast Cancer: Final Overall Survival in the Phase III FALCON Trial.

The randomized phase III FALCON trial demonstrated significant improvement in progression-free survival (PFS) with fulvestrant versus anastrozole in postmenopausal women with endocrine therapy-naïve, hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer. Herein, the prespecified final overall survival (OS) analysis is reported. After the primary PFS analysis, data were collected on survival, serious adverse events, and health-related quality of life.

Injury of the popliteal artery by shrapnel of a Ukrainian girl treated at the University Hospital Ostrava - case report of arterial lesion without acute limb ischemia.

A popliteal artery injury in a 12-year-old female patient, injured in the war conflict in Ukraine, proved to be serious, requiring surgical treatment, despite seemingly poor symptoms and the absence of subjective difficulties. The presentation of arterial injury without acute limb ischemia was atypical. The clinical picture of the lower limb in the sense of "pulseless pink" based on an arterial lesion is not common, but its underestimation can have permanent consequences for the patient.

North Pontic crossroads: Mobility in Ukraine from the Bronze Age to the early modern period.

The North Pontic region, which encompasses present-day Ukraine, was a crossroads of migration, connecting the vast Eurasian Steppe with Central Europe. We generated shotgun-sequenced genomic data for 91 individuals dating from around 7000 BCE to 1800 CE to study migration and mobility history in the region, with a particular focus on historically attested migrating groups during the Iron Age and the medieval period. We infer a high degree of temporal heterogeneity in ancestry, with fluctuating genetic affinities to different present-day Eurasian groups.

Metformin in Antiviral Therapy: Evidence and Perspectives.

Metformin, a widely used antidiabetic medication, has emerged as a promising broad-spectrum antiviral agent due to its ability to modulate cellular pathways essential for viral replication. By activating AMPK, metformin depletes cellular energy reserves that viruses rely on, effectively limiting the replication of pathogens such as influenza, HIV, SARS-CoV-2, HBV, and HCV. Its role in inhibiting the mTOR pathway, crucial for viral protein synthesis and reactivation, is particularly significant in managing infections caused by HIV, CMV, and EBV.

Method for Correcting Error Due to Self-Heating of Resistance Temperature Detectors Suitable for Metrology in Industry 4.0.

This study contributes to improving the accuracy of temperature measurements with a platinum resistance temperature detector (RTD) by proposing techniques to mitigate the error due to self-heating by the operating current. An assessment of the measurement errors of the platinum RTD was carried out to study ways to improve their accuracy. High accuracy can be achieved by individual calibration using a voltage divider circuit to measure resistance, the substitution method, and the transitional measure.

Amperometric Biosensor Based on Glutamate Oxidase to Determine Ast Activity.

This work presents the development of an amperometric biosensor for detecting aspartate aminotransferase (AST) activity in biological fluids using a platinum disk electrode as the working transducer. Optimal concentrations of substrates (aspartate, α-ketoglutarate) and the coenzyme (pyridoxal phosphate) were determined to ensure efficient biosensor operation. A semi-permeable poly-m-phenylenediamine membrane was applied to enhance selectivity against electroactive interferents.

Modification and Use of Naturally Renewable Cardanol-Type Prepolymers in One-Component Silyl-Terminated Prepolymer Sealant Systems.

The current research is devoted to integrating naturally renewable cardanol derivatives into one-component silyl-terminated-polyether-based prepolymer systems to improve climatic resistance and obtain materials with versatile mechanical properties that could be significant to various sectors of the economy. Various cardanol-type products are used in industries that require high climatic resistance, and thus combining cardanol with commercially available silyl-terminated polyether prepolymers would improve its material climatic resistance, maintaining its market and application value as well as improving material sustainability. The results obtained in this work show that depending on how the cardanol prepolymer Ultra Lite 513 is modified, it is possible to increase the elasticity (670%) or tensile strength (104%) of the material as well as significantly increase the climatic resistance of the material, thus improving the quality and sustainability of the adhesive compared to existing silyl-terminated-prepolymer-based adhesives on the market.

Vibration Welding of PLA/PHBV Blend Composites with Nanocrystalline Cellulose.

Thermoplastic composites have garnered significant attention in various industries due to their exceptional properties, such as recyclability and ease of molding. In particular, biocomposites, which combine biopolymers with natural fibers, represent a promising alternative to petroleum-based materials, offering biodegradability and reduced environmental impact. However, there is limited knowledge regarding the efficacy of joining PLA/PHBV-based biocomposites modified with nanocrystalline cellulose (NCC) using vibration welding, which restricts their potential applications.

Analysis of the Impact of the Post-Consumer Film Waste Scenario and the Source of Electricity on the Harmfulness of the Mass Packaging Process.

Life cycle analysis (LCA) is a popular tool for determining the environmental impacts of a product in use. The aim of this study is to carry out a life cycle analysis, gate-to-gate, of a mass packaging process using a polyethylene shrinking film with a focus on energy consumption, raw material use and associated emissions, and film post-consumer disposal scenarios. Two different scenarios for the disposal of the shrinking film used in the packaging process were analyzed, namely recycling and landfills.

α-Tocopherol and Trolox as Effective Natural Additives for Polyurethane Foams: A DFT and Experimental Study.

In this work, α-tocopherol and trolox were studied as compounds that have high biological activity. α-Tocopherol is considered a food additive because the refining process of vegetable oils causes the depletion of this vitamin, and thus, its inclusion is required to keep them from oxidizing. Computational tools have determined the antioxidant activity of these additives.

The Effect of Absorbed Hydrogen on the Rotors of Steel Machining Products During Powerful Turbo Aggregate Repairs.

Rotor shafts are the most heavily loaded and accident-prone parts of powerful turbine generators, which are cooled using hydrogen. To eliminate damage sustained during operations, repair work was carried out, including the removal of defective parts, surfacing, and turning. This study tested the machinability of the rotor shaft using prototypes made from 38KhN3MFA steel.

Geopolymer Foam with Low Thermal Conductivity Based on Industrial Waste.

Geopolymer materials are increasingly being considered as an alternative to environmentally damaging concrete based on Portland cement. The presented work analyzed waste from mines and waste incineration plants as potential precursors for producing geopolymer materials that could be used to make lightweight foamed geopolymers for insulation applications. The chemical and phase composition, radioactivity properties, and leachability of selected precursors were analyzed.

Assessment of the Structural Integrity of the Portal Crane Elements After Long-Term Operation.

Evaluating the current technical condition and residual life of structures that may have reached or exceeded the end of their design life is a challenging issue in many industrial sectors. This paper focuses on the assessment of the structural integrity of structural elements of a seaport portal crane after operation for about 33 years. Test specimens were extracted from two crane elements, a jib (element A) as the most seriously loaded unit and, for comparison, a boom (element B) as the less loaded one, and machined in two different orientations, longitudinal and transversal.

Composites Based on PLA/PHBV Blends with Nanocrystalline Cellulose NCC: Mechanical and Thermal Investigation.

This study investigates the physical and mechanical properties of biodegradable composites based on PLA/PHBV blends modified with different content of nanocrystalline cellulose (NCC) of 5, 10, and 15 wt.%. Density measurements reveal that the density of the composite increases with increasing NCC content.

Granite Dust and Silica Fume as a Combined Filler of Reactive Powder Concrete.

By volume, cement concrete is one of the most widely used construction materials in the world. This requires a significant amount of Portland cement, and the cement industry, in turn, causes a significant amount of CO emissions. Therefore, the development of concrete with a reduced cement content is becoming an urgent problem for countries with a significant level of production and consumption of concrete.

Functional Mechanical Behavior and Biocompatible Characteristics of Graphene-Coated Cardiovascular Stents.

Percutaneous Coronary Intervention (PCI) is a treatment method that involves reopening narrowed arteries with a balloon catheter that delivers a cylindrical, mesh-shaped implant device to the site of the stenosis. Currently, by applying a coating to a bare metal stent (BMS) surface to improve biocompatibility, the main risks after PCI, such as restenosis and thrombosis, are reduced while maintaining the basic requirements for the mechanical behavior of the stent itself. In this work, for the first time, the development and optimization process of the spatial structure of the Co-Cr stent (L-605) with a graphene-based coating using cold-wall chemical vapor deposition (CW-CVD) to ensure uniform coverage of the implant was attempted.

Treatment of Hepatitis C Virus Infections Among Patients of Ukrainian Origin During the Influx of War Refugees to Poland.

The wave of wartime migration from Ukraine has raised a number of concerns about infectious diseases, the prevalence of which is higher in Ukraine than in host countries, with hepatitis C virus (HCV) infection being one of them. Our analysis aimed to assess the percentage of HCV-infected Ukrainian refugees under care in Polish centers providing antiviral diagnosis and therapy, to evaluate their characteristics and the effectiveness of treatment with direct-acting antiviral drugs (DAAs). The analysis included patients of Polish and Ukrainian nationality treated for HCV infection between 2022 and 2024 in Polish hepatology centers.

Prevalence of Abdominal Obesity in Children and Adolescents with Intellectual Disability in Southeastern Poland.

: The aim of the study was to determine the frequency of occurrence of a significant health problem-abdominal obesity (AO)-in children and adolescents with intellectual disability (ID) compared to children and adolescents without disabilities, examined in the period 2013-2014. : The study group included 568 students with various ID degrees ( = 265 mild; = 249 moderate; = 54 severe) (age range 7-18 years) attending care and educational facilities. The comparison group (non-ID) was randomly selected based on the principle of matching the group (age and sex) among students without ID.

Genetic Risk of Ankylosing Spondylitis and Second-Line Therapy Need in Crohn's Disease: A Mendelian Randomization Study.

Crohn's disease (CD) and Ankylosing Spondylitis (AS) are chronic conditions with overlapping inflammatory pathways. This research investigates the genetic association between AS and the requirement for more aggressive therapeutic interventions in CD, suggesting a likelihood of increased severity in CD progression among individuals diagnosed with AS. This study utilized two-sample Mendelian randomization (TSMR) to analyze GWAS datasets for AS and CD requiring second-line treatment.