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Mass spectrometry methods measured androgen and estrogen concentrations during pregnancy and in newborns of mothers with polycystic ovary syndrome.

Eur J Endocrinol

January 2016

Division of Reproductive MedicineDepartment of Obstetrics and Gynaecology, VU University Medical Center (VUmc), Gebouw Zuid, Amstelveenseweg 601, 1081 JC Amsterdam, The NetherlandsARUP Institute for Clinical and Experimental PathologySalt Lake City, Utah, USADepartment of PathologyUniversity of Utah School of Medicine, Salt Lake City, USADepartment of MedicineUniversity of Utah School of Medicine, Salt Lake City, USAHomerton Fertility CentreHomerton University Hospital, London, UK.

Objective: Little is known about the aetiology of polycystic ovary syndrome (PCOS). Some suggest that elevated maternal androgens during gestation play a causative role. This implies placental passage of androgens during pregnancy.

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