2 results match your criteria: "USA. claire.gustafson@alleninstitute.org.[Affiliation]"
Author Correction: Trimodal single-cell profiling reveals a novel pediatric CD8αα T cell subset and broad age-related molecular reprogramming across the T cell compartment.
Nat Immunol
March 2024
Allen Institute for Immunology, Seattle, WA, USA.
Trimodal single-cell profiling reveals a novel pediatric CD8αα T cell subset and broad age-related molecular reprogramming across the T cell compartment.
Nat Immunol
November 2023
Allen Institute for Immunology, Seattle, WA, USA.
Article Synopsis
- * Results indicate that as people age, T cell subsets shift toward a more activated state, and naive CD4 T cells undergo significant genetic changes despite previously being thought resilient to aging.
- * A new subtype of CD8αα T cells, which is lost with age and is important for quick immune responses, was identified, highlighting the complex molecular changes in T cells that may influence how the immune system functions differently