3 results match your criteria: "USA. Electronic address: jxiao@macrohardinstitute.org.[Affiliation]"

Diarrhea predominant irritable bowel syndrome (IBS) is a highly relapsing gastrointestinal disorder decreasing the quality of life. Existing studies indicated that the therapeutic effects maintained for a period of time after the treatments were discontinued (post-treatment therapeutic effects or PTTE). In this study, we aim to assess the PTTE of tongxie.

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8-hydroxypinoresinol-4-O-β-D-glucoside from Valeriana officinalis L. Is a Novel Kv1.5 Channel Blocker.

J Ethnopharmacol

August 2021

The Macrohard Institute of Health, 231 North Ave, Battle Creek, MI, 49017, USA; The American Academy of Tradition Chinese Medicine Inc., 1925 W County Rd B2, Roseville, MN, 55113, USA. Electronic address:

Ethnopharmacology Relevance: In folkloric medicine of many cultures, one of the medical uses of Valeriana officinalis Linn is to treat heart-related disease. Recently, it was shown that the ethanol extracts from V. officinalis could effectively prevent auricular fibrillation, and 8-hydroxypinoresinol-4-O-β-D-glucoside (HPG) from the extracts is one of the two active compounds showing antiarrhythmia activities.

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Article Synopsis
  • The study aimed to assess the effectiveness and safety of personalized tongxie formulas for treating IBS while minimizing type II errors.
  • Patients were assigned to three groups (tongxie, placebo, pinaverium) and evaluated over 4 weeks for improvements in abdominal pain and stool consistency.
  • Results showed that more patients experienced improved stool consistency and reduced stool frequency than pain relief, highlighting the importance of personalization in treatment for various IBS subtypes.
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