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Allergic mechanisms of Eosinophilic oesophagitis.

Best Pract Res Clin Gastroenterol

October 2015

Food Allergy Center at Tufts Medical Center and Floating Hospital for Children, Division of Allergy and Immunology, Division of Gastroenterology and Hepatology, Division of Pediatric Gastroenterology and Nutrition, Tufts Medical Center, Boston, MA, USA. Electronic address:

Eosinophilic oesophagitis (EoE) is characterized by oesophageal dysfunction and oesophageal eosinophilia refractory to proton-pump-inhibitor treatment. EoE is a food allergy, as elimination of food trigger(s) abrogates the disease, while trigger reintroduction causes recurrence. The allergic mechanism of EoE involves both IgE and non-IgE processes.

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