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Impact of perioperative chemotherapy on survival in patients with cholangiocarcinoma undergoing curative resection.

Eur J Surg Oncol

November 2023

Department of Oncology, University Hospitals Seidman Cancer Center and Case Western Reserve University, Cleveland, OH, USA; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA. Electronic address:

Background: Most patients with localized cholangiocarcinoma (CCA) endure cancer relapse after curative resection underscoring the importance of systemic therapy. The current study attempts to determine the impact of perioperative chemotherapy (PC) on survival in patients with CCA undergoing resection.

Methods: Patients diagnosed with CCA undergoing curative-intent resection between January 1, 2000, and December 31, 2019, in a tertiary care center were included.

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