10 results match your criteria: "USA. Cynthia.bearer@UHhospitals.org.[Affiliation]"
The history of diapers and their environmental impact.
Pediatr Res
July 2024
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
This article examines diaper practices around the world throughout history. This article reviews the innovation of the modern diaper and the environmental effects of disposable diapers.
View Article and Find Full Text PDFThe effect of early postnatal auditory stimulation on outcomes in preterm infants.
Pediatr Res
November 2024
Dept of Pediatrics, Case Western Reserve University, Cleveland, OH, 44016, USA.
Preterm infants are deprived of in utero sensory stimulation during the third trimester, an important period of central nervous system development. As a result, maturational trajectories are often reduced in infants born preterm. One such system affected is the brain including the auditory and respiratory control pathways.
View Article and Find Full Text PDFCholine supplementation mitigates effects of bilirubin in cerebellar granule neurons in vitro.
Pediatr Res
July 2024
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Background: Premature infants may suffer from high levels of bilirubin that could lead to neurotoxicity. Bilirubin has been shown to decrease L1-mediated ERK1/2 signaling, L1 phosphorylation, and L1 tyrosine 1176 dephosphorylation. Furthermore, bilirubin redistributes L1 into lipid rafts (LR) and decreases L1-mediated neurite outgrowth.
View Article and Find Full Text PDFGlobal climate change: the defining issue of our time for our children's health.
Pediatr Res
September 2022
Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Mountain View, CA, USA.
Thirty-two steps for getting your R01: advice to early career investigators.
Pediatr Res
March 2023
Rainbow Babies & Children's Hospital and Case Western Reserve University, Cleveland, OH, USA.
Neonatal hypoxia ischemia redistributes L1 cell adhesion molecule into rat cerebellar lipid rafts.
Pediatr Res
November 2022
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Background: Hypoxic-ischemic encephalopathy (HIE) is a devastating disease with lifelong disabilities. Hypothermia is currently the only treatment. At term, the neonatal cerebellum may be particularly vulnerable to the effects of HIE.
View Article and Find Full Text PDFValue of children in our world.
Pediatr Res
November 2022
Paediatrics, Trinity College, the University of Dublin, Dublin, Ireland.
Factors that influence citations to articles published in Pediatric Research.
Pediatr Res
September 2022
Rainbow Babies & Children's Hospital of Cleveland, Cleveland, OH, USA.
Bilirubin inhibits lipid raft dependent functions of L1 cell adhesion molecule in rat pup cerebellar granule neurons.
Pediatr Res
May 2021
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Background: The mechanism of bilirubin neurotoxicity is poorly understood. We hypothesize that bilirubin inhibits the function of lipid rafts (LR), microdomains of the plasma membrane critical for signal transduction. To test this hypothesis, we measured the effect of free bilirubin (Bf) between 7.
View Article and Find Full Text PDFHigh concentrations of urinary ethanol metabolites in neonatal intensive care unit infants.
Pediatr Res
December 2020
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Background: Infants in the neonatal intensive care unit may be exposed to ethanol via medications that contain ethanol as an excipient and through inhalation of ethanol vapor from hand sanitizers. We hypothesized that both pathways of exposure would result in elevated urinary biomarkers of ethanol.
Methods: Urine samples were collected from infants in incubators and in open cribs.