27 results match your criteria: "USA. Broad Institute of MIT and Harvard[Affiliation]"
RNA Function. RNA and dynamic nuclear organization.
Science
September 2014
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Cosi2: an efficient simulator of exact and approximate coalescent with selection.
Bioinformatics
December 2014
Broad Institute of MIT and Harvard, MA 02142 and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
Motivation: Efficient simulation of population genetic samples under a given demographic model is a prerequisite for many analyses. Coalescent theory provides an efficient framework for such simulations, but simulating longer regions and higher recombination rates remains challenging. Simulators based on a Markovian approximation to the coalescent scale well, but do not support simulation of selection.
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