1 results match your criteria: "USA bUniversity of British Columbia Clinician Investigator Program[Affiliation]"

Clinical applications of next-generation sequencing in histocompatibility and transplantation.

Curr Opin Organ Transplant

August 2015

aDepartment of Pathology & Laboratory Medicine, UCLA Immunogenetics Center, Los Angeles, California, USA bUniversity of British Columbia Clinician Investigator Program, Vancouver, British Columbia, Canada.

Purpose Of Review: Next-generation sequencing (NGS) can overcome traditional methodological barriers to facilitate detailed studies of large genomes. Here, we summarize recent NGS-based developments in histocompatibility and transplantation, and highlight the dynamic range of clinical applications achievable on this platform.

Recent Findings: Multiple NGS-based protocols have been established to achieve unambiguous human leukocyte antigen genotyping.

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