1 results match your criteria: "USA bUniversity Teaching Hospital-Lusaka Children's Hospital cUniversity of Zambia School of Medicine[Affiliation]"
HIV drug resistance in infants increases with changing prevention of mother-to-child transmission regimens.
AIDS
August 2017
aNebraska Center for Virology and School of Biological Sciences, University of Nebraska, Lincoln, Nebraska, USA bUniversity Teaching Hospital-Lusaka Children's Hospital cUniversity of Zambia School of Medicine, Lusaka, Zambia.
Objectives: The objectives of this study were to determine HIV drug resistance (HIVDR) prevalence in Zambian infants upon diagnosis, and to determine how changing prevention of mother-to-child transmission (PMTCT) drug regimens affect drug resistance.
Design: Dried blood spot (DBS) samples from infants in the Lusaka District of Zambia, obtained during routine diagnostic screening, were collected during four different years representing three different PMTCT drug treatment regimens.
Methods: DNA extracted from dried blood spot samples was used to sequence a 1493 bp region of the reverse transcriptase gene.