Autoantibodies against the envelope proteins of endogenous retroviruses K102 and K108 in patients with systemic lupus erythematosus correlate with active disease.

Objectives: To determine if patients with systemic lupus erythematosus (SLE), a disease characterised by elevated type I interferons reminiscent of anti-viral immunity, have expression of human endogenous retrovirus K (HERV-K) proviruses capable of producing envelope (Env) protein, as well as associated autoantibodies against the Env protein.

Methods: ELISAs were conducted with recombinant Env protein and sera from SLE patients with active (n=60) or inactive (n=49) disease, healthy controls (n=47), other rheumatic disorders (n=59), as well as plasma from paediatric lupus patients with active (n=30) or inactive (n=30) disease, and 17 healthy children. Antibody reactivity was evaluated for correlations with clinical and laboratory parameters of the patients.

Are clinic-based walking measures associated with community walking activity in children with cerebral palsy?

Purpose: To examine the relationship between clinic-based walking capacity measures and community-based walking activity in ambulatory children with cerebral palsy (CP).

Methods: A secondary analysis of a cross-sectional cohort was employed at tertiary care children's hospital; n= 128, ages 2-9 years, Gross Motor Function Classification System (GMFCS) I-III. Walking capacity was captured with 1- and 6-minute walk tests (1MWT, 6MWT), Gross Motor Function Measure-walk/run/jump score (GMFM-E), and Activity Scale for Kids performance version (ASKp-30).

"I wasn't texting; I was just reading an email …": a qualitative study of distracted driving enforcement in Washington State.

Background: In response to the rise of distracted driving, many countries and most US states have adopted laws to restrict the use of handheld phones for drivers. Specific provisions of each law and the overall social mores of distracted driving influence enforceability and impact.

Objectives: Identify multilevel interdependent factors that influence distracted driving enforcement through the perspective of police officers.

Pedestrian signalization and the risk of pedestrian-motor vehicle collisions in Lima, Peru.

Safe walking environments are essential for protecting pedestrians and promoting physical activity. In Peru, pedestrians comprise over three-quarters of road fatality victims. Pedestrian signalization plays an important role managing pedestrian and vehicle traffic and may help improve pedestrian safety.

Bus stops and pedestrian-motor vehicle collisions in Lima, Peru: a matched case-control study.

Objective: To evaluate the relationship between bus stop characteristics and pedestrian-motor vehicle collisions.

Methods: This was a matched case-control study where the units of study were pedestrian crossings in Lima, Peru. We performed a random sample of 11 police commissaries in Lima, Peru.

The utility of adding expiratory or decubitus chest radiographs to the radiographic evaluation of suspected pediatric airway foreign bodies.

Study Objective: This study aimed to compare test characteristics of standard (lateral and posteroanterior or anteroposterior) chest radiographs with and without special views (expiratory or bilateral decubitus) in the emergency department evaluation of children with suspected airway foreign bodies.

Methods: From 1997 to 2008, 328 patients with a suspected airway foreign body had standard and special view chest radiographs: 192 with left and right decubitus views, 133 with expiratory views, and 3 with both. Patients were excluded for cardiorespiratory disease, chest wall deformity, visible airway foreign bodies on standard views, or spontaneously expelled airway foreign bodies.