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National Breakthrough Pain Study: prevalence, characteristics, and associations with health outcomes.

Pain

February 2015

Teva Pharmaceuticals, Frazer, PA, USA Tufts University School of Medicine, Boston, MA, USA Analgesic Solutions, Natick, MA, USA EPI-Q, Inc, Oak Brook, IL, USA HealthCore, Inc, Wilmington, DE, USA Thayer County Health Services, Hebron, NE, USA MJHS Institute for Innovation in Palliative Care, New York, NY, USA.

Article Synopsis
  • The National Breakthrough Pain Study examined breakthrough pain (BTP) in patients with chronic pain being treated with opioids, utilizing interviews and validated questionnaires to gather comprehensive data.
  • Out of 2198 patients, 80% experiencing persistent pain reported an average of 2 daily episodes of BTP, lasting around 45 minutes each, with significant variability in both frequency and duration.
  • Patients with BTP showed greater interference with daily function, worse physical and mental health, increased disability, and poorer mood compared to those without BTP, highlighting a need for targeted treatment strategies.
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