5,624,886 results match your criteria: "USA; Sandra and Edward Meyer Cancer Center[Affiliation]"

Regrowth Rate of a Cardiac Myxoma After Percutaneous Aspiration.

JACC Case Rep

January 2025

Department of Cardiology, Lankenau Medical Center, Wynnewood, Pennsylvania, USA.

Cardiac myxomas are typically treated surgically; however, the operative mortality and recurrence rates are not negligible. In the current report we describe a case of repeat percutaneous aspiration of a right atrial myxoma. The report supports feasibility of the procedure, provides the asymptomatic timeframe after debulking, and the regrowth rate.

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Surgical resection is standard of care for the treatment of atrial myxoma. However, the optimal management strategy for recurrent cardiac tumors is less clear. Here we report the novel use of a catheter-based device retrieval system for the removal of a recurrent cardiac myxoma.

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The transcatheter management of complex cardiovascular diseases has significantly evolved, offering less invasive alternatives to traditional surgical interventions. In this report we describe 2 cases of patients who developed ascending aortic pseudoaneurysms soon after coronary artery bypass grafting. With meticulous computed tomography angiography planning and with live intracardiac echography, these patients underwent successful transcatheter repair using a 6/4-mm Amplatzer Duct Occluder II (Abbott) vascular plug.

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Percutaneous coronary intervention of a severely calcified coronary artery stenosis is associated with stent underexpansion and adverse outcomes. Intravascular lithotripsy (IVL) is a novel technology for fracturing calcified plaque in the coronary artery. We describe the first case of a severely calcified, undilatable coronary artery lesion.

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Unzipping the Challenges of Total Endovascular Aortic Arch Replacement.

JACC Case Rep

January 2025

Bluhm Cardiovascular Institute and Division of Cardiac Surgery, Northwestern Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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Gunshot-related myocardial injuries typically result from direct penetrating injury by the traversing bullet. We present a case of gunshot-related myocardial injury in the absence of direct penetrating injury to the cardiac structures and describe alternative mechanisms for ballistic-induced injury.

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Extracavitary cardiac calcific amorphous tumors/masses are extremely rare. We present a case report of a 62-year-old man with end-stage renal disease who presented with extracavitary cardiac calcific amorphous tumors/masses compressing the biventricular outflow tracts, resulting in hemodynamic compromise and progressive limitation of activities. The patient was successfully treated with surgery, with complete resolution of symptoms and markedly improved quality of life.

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This case report describes the management of a 30-year-old male patient with a history of an advanced nonseminomatous germ cell tumor, hip fracture complicated by extensive deep vein thrombosis and pulmonary embolism, and on apixaban presenting with asymptomatic intracardiac teratoma and abdominopelvic metastases. Multidisciplinary intervention, including successful surgical excision of the intracardiac mass, highlights the importance of coordinated care and vigilant follow-up in optimizing patient outcomes and preventing life-threatening complications.

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Tongue Squamous Cell Carcinoma With Cardiac Metastases.

JACC Case Rep

January 2025

Division of Cardiology, Wayne State University, Detroit Medical Center, Detroit, Michigan, USA.

A 60-year-old man with squamous cell carcinoma of the tongue had atypical chest pain and mild troponin elevation. No significant electrocardiogram changes or arrhythmias were noted. Cardiac magnetic resonance revealed several myocardial metastases with pericardial involvement, confirmed by positron emission tomography/computed tomography.

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A 79-year-old woman, previously treated for congenital pulmonary valve stenosis through surgical and transcatheter procedures, presented with worsening dyspnea. This led to the identification of valve thrombosis in her bioprosthetic pulmonary valve. This report delves into the clinical importance of obstructive valve thrombosis, its diagnostic assessment, and potential therapeutic strategies.

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Paravalvular leak (PVL) following transcatheter aortic valve replacement (TAVR) is an established complication, albeit rarely associated with hemolytic anemia. This report details 3 cases of significant hemolytic anemia attributed to TAVR-induced PVL, each with distinct clinical presentations and manifestations. These cases underscore the diverse and occasionally subtle clinical presentation of aortic PVL-associated hemolytic anemia.

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This case series highlights the role of endomyocardial biopsy (EMB) in diagnosing cardiac tumors instead of tumor resection. EMB provided critical diagnostic clarity and influenced therapeutic decisions, demonstrating its utility in complex cardiovascular cases while preventing unnecessary surgery. Furthermore, EMB provides vital information that can be used for a multidisciplinary approach to cardiac tumors.

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Left ventricular outflow tract (LVOT) obstruction is mostly caused by hypertrophic obstructive cardiomyopathy and subaortic stenosis. Rarely, malignancy can lead to dynamic LVOT obstruction and has only been sporadically documented. We present the first case of dynamic and/or nearly fixed LVOT obstruction caused by a cardiac myxoid spindle cell sarcoma.

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TEER for SAM of the Mitral Valve and Flail Posterior Mitral Leaflet: 1-Clip Solution.

JACC Case Rep

January 2025

Department of Cardiovascular Medicine, Richmond Heart & Vascular Associates, Richmond, Virginia, USA.

Transcatheter edge-to-edge repair (TEER) is approved for patients with symptomatic severe mitral regurgitation (MR) who are deemed inoperable or at high surgical risk with life expectancy of more than 1 year, but has also been used off-label in patients with hypertrophic obstructive cardiomyopathy (HOCM) for symptomatic relief who are not candidates for septal reduction therapy. An 83-year-old woman with decompensated heart failure was found to have HOCM with systolic anterior motion of the mitral valve and a large P2 flail segment with ruptured cords. TEER was performed resulting in mild MR and resolution of the prior left ventricular outflow tract gradient.

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Transcatheter Aortic Valve Replacement in Patients With Interventricular Membranous Septal Aneurysms.

JACC Case Rep

January 2025

Interventional Cardiology Section, Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

Aneurysms of the interventricular membranous septum are a rare anatomical feature that can be detected incidentally on computed tomography or echocardiography. Such aneurysms can pose challenges in the treatment of patients with aortic valve stenosis. A case series of 2 patients with membranous septal aneurysms treated successfully with current-generation balloon-expandable and self-expanding transcatheter heart valves is presented here.

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Background: This study aims to assess the relationships between sphenoid sinus (SS) types, septation, lobulation, symmetry, septal deviation, and the variations in SS pneumatization regarding the surrounding neurovascular structures using Computed tomography (CT) images. Sexes and age groups were investigated.

Material And Methods: We retrospectively evaluated head CT-scans of 320 patients (age range 18-49 years); mean of 43.

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Current models for the study of neuroendocrine tumours (NETs) are severely limited. While (e.g.

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An Acellular Platform to Drive Urinary Bladder Tissue Regeneration.

Adv Ther (Weinh)

January 2025

Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Division of Pediatric Urology, Department of Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA; Center for Regenerative Nanomedicine, Northwestern University, Chicago, IL 60611, USA; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.

Impaired bladder compliance secondary to congenital or acquired bladder dysfunction can lead to irreversible kidney damage. This is managed with surgical augmentation utilizing intestinal tissue, which can cause stone formation, infections, and malignant transformation. Co-seeded bone marrow mesenchymal stem cell (MSC)/CD34+ hematopoietic stem cell (HSPC) scaffolds (PRS) have been successful in regenerating bladder tissue.

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Background: Response to induction chemotherapy has been shown to predict outcome in patients with high-risk neuroblastoma (HR-NB), with those achieving a complete response (CR) having superior outcomes.

Methods: We evaluated whether conventional prognostic factors remain prognostic in subsets of patients defined by response to induction. 1244 Patients from four COG high-risk trials were included.

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Unlabelled: The combination of hypertrophic cardiomyopathy with outflow tract obstruction, severe pre-capillary and post-capillary pulmonary hypertension, and severe primary mitral regurgitation is rare and presents distinct management challenges.

Background And Clinical Significance: Pulmonary hypertension is an independent predictor of all-cause mortality in patients with hypertrophic cardiomyopathy managed medically and often precludes patients from undergoing cardiopulmonary bypass due to increased surgical morbidity and mortality. In studies specifically evaluating surgical myectomy, however, survival is favorable in patients with moderate-to-severe pulmonary hypertension.

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Predictors of anterior chamber angle status at the time of neovascular glaucoma diagnosis.

Am J Ophthalmol Case Rep

December 2024

Department of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL, USA.

Purpose: To identify clinical features which may predict the angle status of a large cohort of NVG eyes at the time of diagnosis.

Observations: Chart review was performed for all NVG eyes from 2010 to 2022. Complete angle closure was defined as having >75 % PAS, partial angle closure as having 1-75 % PAS, and open angles as having 0 % PAS.

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Purpose: To report the case of a woman in her fifties whose presenting symptom of idiopathic intracranial hypertension was engorgement of the eyelid veins.

Observations: Bilateral engorged palpebral veins were visible through the skin. Dilated fundus examination revealed bilateral optic disc edema.

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