Effects of fire recurrence and severity on Mediterranean vegetation dynamics: Implications for structure and composition in southern Spain.

Most Mediterranean ecosystems have been profoundly shaped by wildfires, driving the evolution of plant species. Through photo interpretation and field inventories, this research assessed vegetation dynamics from 1984 to 2021, examining how fire severity and recurrence, key fire regime variables, influenced changes in structure and woody species diversity. Using two burn scars (1988 and 2006), we identified four scenarios dominated by Pinus pinea tree species: control (unburned), areas burned once (either in 1988 or 2006), and twice (in both 1988 and 2006).

Impact of water, sanitation, and hygiene indicators on enteric viral pathogens among under-5 children in low resource settings.

Poor water, sanitation, and hygiene (WASH) are the primary risks of exposure to enteric viral infection. Our study aimed to describe the role of WASH conditions and practices as risk factors for enteric viral infections in children under 5. Literature on the risk factors associated with all-cause diarrhea masks the taxa-specific drivers of diarrhea from specific pathogens, limiting the application of relevant control strategies.

Anterior pituitary gland volume mediates associations between adrenarche and changes in transdiagnostic symptoms in youth.

The pituitary gland (PG) plays a central role in the production and secretion of pubertal hormones, with documented links to the increase in mental health symptoms during adolescence. Although literature has largely focused on examining whole PG volume, recent findings have demonstrated associations among pubertal hormone levels, including dehydroepiandrosterone (DHEA), PG subregions, and mental health symptoms during adolescence. Despite the anterior PG's role in DHEA production, studies have not yet examined potential links with transdiagnostic symptomology (i.

Identification of key gene signatures for predicting chemo-immunotherapy efficacy in extensive-stage small-cell lung cancer using machine learning.

Objectives: The lack of definitive biomarkers presents a significant challenge for chemo-immunotherapy in extensive-stage small-cell lung cancer (ES-SCLC). We aimed to identify key genes associated with chemo-immunotherapy efficacy in ES-SCLC through comprehensive gene expression analysis using machine learning (ML).

Methods: A prospective multicenter cohort of patients with ES-SCLC who received first-line chemo-immunotherapy was analyzed.

The utility of multiple assessments in infancy and toddlerhood to predict middle childhood ADHD symptoms: Temperamental, behavioral, and genetic contributions.

Background: Early intervention is effective for reducing ADHD symptoms and related impairments, yet methods of identifying young children in need of services are lacking. Most early predictors of ADHD previously identified are of limited clinical utility. This study examines several theoretically relevant predictors of ADHD in infancy and toddlerhood and whether assessment at multiple time points improves prediction.

Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission.

Cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity globally. It is estimated that 17.9 million people died from CVDs in 2019, which represents 32 % of all deaths worldwide.

Visual analysis of the research frontiers, hotspots and development trends of immunization programs for women and children.

The objective of this study is to gain insight into the current research frontiers, hotspots, and development trends in the field of immunization programs for women and children, and to provide scientific guidance and reference for follow-up research. Based on all the original research papers related to the research on immunization programs for women and children in the Web of Science Core Collection (WoSCC) database, bibliometric studies and visual analysis were carried out to explore the research frontiers, hotspots and development trends, and to analyze the risk factors affecting the vaccination coverage of immunization programs for women and children. Eight hundred forty-three papers obtained from 1,552 institutions in 96 countries/regions from January 1950 to August 2024, coauthored by 4,343 authors.

A shared serial order system for verbal working memory and language production: evidence from aphasia.

Many aspects of human performance require producing sequences of items in serial order. The current study takes a multiple-case approach to investigate whether the system responsible for serial order is shared across cognitive domains, focusing on working memory (WM) and word production. Serial order performance in three individuals with post-stroke language and verbal WM disorders (hereafter persons with aphasia, PWAs) were assessed using recognition and recall tasks for verbal and visuospatial WM, as well as error analyses in spoken and written production tasks to assess whether there was a tendency to produce the correct phonemes/letters in the wrong order.

Preventing Community-Acquired Pressure Injury in Spinal Cord Injury: Simulation for Registered Nurses.

Purpose: The study purpose was to develop and assess a simulation for registered nurses to apply knowledge, skills, and attitudes in conducting a focused assessment in the clinic setting to prevent community-acquired pressure injuries (CAPrIs) in individuals living with spinal cord injury (SCI).

Methods: Development, psychometric assessment, and pilot of a simulation for a nurse-patient clinic appointment to prevent CAPrIs at home. Evaluations were conducted via focus group.

Investigation of the Content Offered to the Public Regarding Noise Pollution in Online News.

Background/objectives: Noise remains an under-discussed type of environmental pollutant, which exerts a wide range of adverse health effects, both auditory and non-auditory. Ensuring that the public has ready access to useful health information online about noise exposure is important. In this regard, evaluating the content of public news articles regarding noise pollution is vital.

Usability of a Cloud-Based Home Healthcare Client Monitoring Platform: A Simulation-Based Approach.

Purpose: The aim of this study was to assess the usability of a cloud-based home healthcare monitoring platform (CHHM).

Design: A proof of concept using a simulated client scenario was used in this study.

Methods: Using a mixed-methods approach, a convenience sample of 14 nursing students was used to assess the usability of CHHM during a simulation.

Bromelain-based enzymatic debridement: mechanism of action in the wound environment. A literature review.

Background: Chronic hard-to-heal wounds, such as diabetic foot ulcers, venous leg ulcers, and pressure ulcers, present significant safety concerns, patient burdens, and challenges to health care systems globally.

Objective: To review the mechanism of action and clinical function of bromelain-based enzymatic debridement (BBD) in the context of wound care, focusing on the mechanism of action of BBD and its formulation for chronic wounds in particular.

Methods: A literature review was conducted to assess both bromelain's mechanism of action as well as clinical and preclinical studies on the use of BBD, searching the PubMed and Google Scholar databases for articles published between November 1992 and July 2024.

In vivo selection of hepatocytes.

The liver is a highly regenerative organ capable of significant proliferation and remodeling during homeostasis and injury responses. Experiments of nature in rare genetic diseases have illustrated that healthy hepatocytes may have a selective advantage, outcompete diseased cells, and result in extensive liver replacement. This observation has given rise to the concept of therapeutic liver repopulation by providing an engineered selective advantage to a subpopulation of beneficial hepatocytes.

Plasma anti-CD4 IgG levels are associated with poor immune recovery in people with HIV initiating antiretroviral therapy.

A segment of people with HIV on effective antiretroviral therapy (ART) continue to experience poor immune recovery, leaving them at heightened risk of non-AIDS-defining events (NAEs). The production of anti-CD4 IgG autoreactive antibodies is suggested as one contributing mechanism to these complications. Here, we found that plasma anti-CD4 levels do not discriminate immunological responders from nonresponders nor predict the occurrence of NAEs, suggesting it is unlikely a contributing immunopathological factor associated with these complications.

Contribution of cognitive status on admission to mobility and balance at discharge from acute rehabilitation for stroke.

Acute inpatient rehabilitation is crucial for improving mobility and balance for individuals with stroke. A potentially important factor in the recovery of mobility and balance is cognition. The purpose of this study was to determine the effect of cognition on mobility and balance in acute stroke rehabilitation.

Incidence and influential factors of postoperative pruritus in morphine-based intravenous patient-controlled analgesia.

Background: Pruritus is a distressing symptom of systemic opioid analgesia that responds poorly to conventional antipruritus treatments. This study aimed to determine the incidence and risk factors for postoperative pruritus using intravenous patient-controlled analgesia (IV-PCA).

Methods: Opioid-naïve patients who underwent morphine-based IV-PCA for postoperative pain at a tertiary center between January 1, 2020, and June 30, 2023, were included retrospectively.

Comparison of EEG Signal Characteristics of Subdural and Depth Electrodes.

Objectives: Our study aimed to compare signal characteristics of subdural electrodes (SDE) and depth stereo EEG placed within a 5-mm vicinity in patients with drug-resistant epilepsy. We report how electrode design and placement collectively affect signal content from a shared source between these electrode types.

Methods: In subjects undergoing invasive intracranial EEG evaluation at a surgical epilepsy center from 2012 to 2018, stereo EEG and SDE electrode contacts placed within a 5-mm vicinity were identified.

Does Merit-based Incentive Payment System Performance Differ Based on Orthopaedic Surgeon Gender?

Background: Value-based care payment and delivery models such as the recently implemented Merit-based Incentive Payment System (MIPS) aim to both provide better care for patients and reduce costs of care. Gender disparities across orthopaedic surgery, encompassing reimbursement, industry payments, referrals, and patient perception, have been thoroughly studied over the years, with numerous disparities identified. However, differences in MIPS performance based on orthopaedic surgeon gender have not been comprehensively evaluated.

Replay as a Basis for Backpropagation Through Time in the Brain.

How episodic memories are formed in the brain is a continuing puzzle for the neuroscience community. The brain areas that are critical for episodic learning (e.g.

Impact of High- and Low-Pass Acoustic Filtering on Audiovisual Speech Redundancy and Benefit in Children.

Objectives: To investigate the influence of frequency-specific audibility on audiovisual benefit in children, this study examined the impact of high- and low-pass acoustic filtering on auditory-only and audiovisual word and sentence recognition in children with typical hearing. Previous studies show that visual speech provides greater access to consonant place of articulation than other consonant features and that low-pass filtering has a strong impact on perception on acoustic consonant place of articulation. This suggests visual speech may be particularly useful when acoustic speech is low-pass filtered because it provides complementary information about consonant place of articulation.