2,253 results match your criteria: "US Army Institute of Surgical Research & Burn Center[Affiliation]"
Front Bioeng Biotechnol
November 2024
Organ Support and Automation Technologies Group, U.S. Army Institute of Surgical Research, San Antonio, TX, United States.
Introduction: Hemorrhage remains the leading cause of preventable death on the battlefield. The most effective means to increase survivability is early hemorrhage control and fluid resuscitation. Unfortunately, fluid resuscitation requires constant adjustments to ensure casualty is properly managed, which is often not feasible in the pre-hospital setting.
View Article and Find Full Text PDFPsychiatry Res
December 2024
Institute for Trauma Recovery, Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA; Department of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA.
J Burn Care Res
November 2024
LSUHSC-New Orleans Health Sciences Center Dept of Surgery, University Medical Center-New Orleans Burn Unit, New Orleans, LA, USA.
We performed a needs assessment to determine the essential elements for a curriculum teaching burn care during Large Scale Combat Operations against peer/near-peer adversaries within multi-domain contested combat environments. Virtual and face-to-face site visit meetings were conducted with 20 stakeholders at 3 levels: 1) Subject Matter Experts (SMEs) in military burn casualty care at the U.S.
View Article and Find Full Text PDFBurns
February 2025
Department of Otolaryngology - Head and Neck Surgery, Brooke Army Medical Center, JBSA Fort Sam Houston, TX, USA; United States Army Institute of Surgical Research, JBSA Fort Sam Houston, TX, USA; Department of Otolaryngology - Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Pathog Dis
February 2024
Division of Combat Wound Repair, U.S. Army Institute of Surgical Research, 3698 Chambers Pass, Building 3610, JBSA Fort Sam Houston, San Antonio, TX 78234-7767, United States.
Cutaneous burn trauma, compromise of dermal layers and immune defense system is a physical and fiscal burden on healthcare systems. Burn-wound infections are a serious complication of thermal injury and contribute significantly to care burden. After burn-induced trauma, sepsis by Pseudomonas aeruginosa impairs patient recovery and contributes to mortality and morbidity.
View Article and Find Full Text PDFExp Hematol Oncol
October 2024
Department of Thoracic Surgery, Institution of Thoracic Oncology, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, Xicheng District, China.
Ann Intern Med
December 2024
Aeromedical Consultation Service, U.S. Air Force School of Aerospace Medicine, Wright-Patterson Air Force Base, Ohio; Wright State University Boonshoft School of Medicine, Dayton, Ohio; and Uniformed Services University F. Edward Hebert School of Medicine, Bethesda, Maryland (A.W.F.).
Description: Headache medicine and therapeutics evidence have been rapidly expanding and evolving since the 2020 U.S. Department of Veterans Affairs (VA) and U.
View Article and Find Full Text PDFClin Exp Dent Res
December 2024
Combat Wound Care Group, US Army Institute of Surgical Research, San Antonio, Texas, USA.
Objectives: The effective control of dental plaque is crucial for oral health, given that pathogenic bacteria in plaque are the primary cause of dental caries. Current antimicrobial agents, although effective, disrupt the oral microbiome and lead to oral dysbiosis, hindering efforts to curb dental caries. Novel antimicrobial peptides offer a promising solution due to their selective bactericidal activity against cariogenic bacteria.
View Article and Find Full Text PDFTop Companion Anim Med
December 2024
School of Veterinary Medicine, Texas A&M University, College Station, TX.
Traumatic brain injuries (TBI) are common in dogs and cats that have sustained head trauma from a variety of causes. In moderate to severe TBI, damage from both the primary and secondary injuries can be life-threatening. TBI management may be further complicated by concurrent injuries in polytrauma patients.
View Article and Find Full Text PDFFront Physiol
October 2024
Mechanical Engineering, University of Maryland, College Park, MD, United States.
Mil Med
October 2024
Craniofacial Health & Restorative Medicine, Naval Medical Research Unit San Antonio, JBSA Fort Sam Houston, TX 78234, USA.
Introduction: Since the start of the Russo-Ukrainian war, most reports have focused on trauma and combat conditions. Trauma care is essential; however, disease and nonbattle injuries (DNBIs) also burden armies and reduce combat effectiveness. Dental emergencies (DEs) account for a substantial portion of DNBI, but there is limited information on Ukrainian military dental readiness.
View Article and Find Full Text PDFAm J Vet Res
December 2024
Department of Emergency Medicine, School of Medicine, University of Utah, Salt Lake City, UT.
Objective: To utilize sidestream dark field video microscopic technology to evaluate the endothelium in a canine hemorrhagic shock and resuscitation model.
Methods: 6 purpose-bred adult dogs were anesthetized, instrumented, and subjected to hemorrhagic shock from September 2021 through June 2022. Each dog was resuscitated with 5 resuscitation strategies in an experimental crossover design study: (1) lactated Ringer's solution (LRS) and hydroxyethyl starch (HES) solution; (2) canine chilled whole blood (CWB); (3) canine fresh frozen plasma (FFP) and packed RBCs (pRBC); (4) canine freeze-dried plasma (FDP) and hemoglobin-based oxygen carrier (HBOC); or (5) HBOC/FDP and canine lyophilized platelets.
Knee Surg Sports Traumatol Arthrosc
September 2024
Department of Orthopedic, Center for Joint Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Burns
December 2024
Infectious Disease Service, Brooke Army Medical Center, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, TX 78234, United States.
Cancer Res Commun
November 2024
Department of Metabolism and Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.
Unlabelled: To increase the achievement of negative R0 surgical margins and increase the low survival rates of pancreatic cancer, improvements in assessing tumor margins during surgical resections are needed. This can be accomplished by using pancreatic cancer-targeted fluorescence molecular imaging agents to intraoperatively detect tumor margins in real time. Because Toll-like receptor 2 (TLR2) is broadly expressed among many cancer types including pancreatic adenocarcinomas, a high-affinity TLR2-targeted fluorescence molecular imaging agent (TLR2L-800) was developed.
View Article and Find Full Text PDFInt J Burns Trauma
August 2024
Brooke Army Medical Center Fort Sam Houston, Texas, USA.
Mil Med
November 2024
Extremity Trauma and Amputation Center of Excellence, JBSA Ft. Sam Houston, TX 78234, USA.
Introduction: In prolonged care scenarios, where medical evacuations are significantly delayed, the treatment and transport of casualties with extremity musculoskeletal injuries will drain combat units' human resources. Developing enhanced splinting techniques to restore casualty mobility and function can alleviate this drain. To guide this development, a panel of tactical combat and wilderness medicine experts was assembled to determine which extremity musculoskeletal injuries had the greatest impact on unit capabilities, and the materials available for splinting these injuries.
View Article and Find Full Text PDFLancet Child Adolesc Health
October 2024
Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA; Susan B Meister Child Health Evaluation and Research Center, Division of General Pediatrics, Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA. Electronic address:
J Spec Oper Med
October 2024
US Air Force School of Aerospace Medicine-Air Force Research Lab, Wright-Patterson Air Force Base, OH.
Building on our strategic framework and operational model, we will discuss findings from our ethnographic study entitled, "The Impact of Catastrophic Injury Exposure on Resilience in Special Operations Surgical Teams (SOST)." Our goal is to establish that medical-martial creativity supports Special Operation Forces (SOF) medics' ability to fluidly modulate pressure amid real-time military medical decision-making in austere environments. We will use qualitative quotes to explore how SOST medics express medical-martial creativity in support of unconventional resilience.
View Article and Find Full Text PDFFront Artif Intell
August 2024
U.S. Army Institute of Surgical Research, JBSA Fort Sam Houston, San Antonio, TX, United States.
Introduction: Hemorrhage remains a leading cause of death in civilian and military trauma. Hemorrhages also extend to military working dogs, who can experience injuries similar to those of the humans they work alongside. Unfortunately, current physiological monitoring is often inadequate for early detection of hemorrhage.
View Article and Find Full Text PDFMil Med
August 2024
Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Surg Endosc
October 2024
Walter Reed National Military Medical Center, 8901 Wisconsin Ave, Bethesda, MD, 20814, USA.
Vet J
October 2024
From the US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX, United States; School of Veterinary Medicine, Texas A&M University, College Station, TX, United States.
Hemorrhagic shock and subsequent resuscitation can cause significant dysregulation of critical systems, including the vascular endothelium. Following hemorrhage, the endothelial lining (glycocalyx) can shed, causing release of glycocalyx components, endothelial activation, and systemic inflammation. A canine model of hemorrhagic shock was used to evaluate five resuscitation fluids, including Lactated Ringers+Hetastarch, Whole Blood (WB), Fresh Frozen Plasma+packed Red Blood Cells (FFP+pRBC), and two hemoglobin-based oxygen carrier (HBOC) fluids, for their impact on glycocalyx shedding.
View Article and Find Full Text PDFJ Burn Care Res
November 2024
Joint Trauma System, U.S. Department of Defense, Fort Sam Houston, TX 78234, USA.