Population-based hospitalization burden estimates for respiratory viruses, 2015-2019.

Background: Acute respiratory infections (ARIs) result in millions of illnesses and hundreds of thousands of hospitalizations annually in the United States. The responsible viruses include influenza, parainfluenza, human metapneumovirus, coronaviruses, respiratory syncytial virus (RSV), and human rhinoviruses. This study estimated the population-based hospitalization burden of those respiratory viruses (RVs) over 4 years, from July 1, 2015 to June 30, 2019, among adults ≥18 years of age for Allegheny County (Pittsburgh), Pennsylvania.

Physical Therapist Management of Total Knee Arthroplasty.

A clinical practice guideline on total knee arthroplasty was developed by an American Physical Therapy (APTA) volunteer guideline development group that consisted of physical therapists, an orthopedic surgeon, a nurse, and a consumer. The guideline was based on systematic reviews of current scientific and clinical information and accepted approaches to management of total knee arthroplasty.

Safety of Bifidobacterium animalis Subsp. Lactis (B. lactis) Strain BB-12-Supplemented Yogurt in Healthy Children.

Objectives: Probiotics are live microorganisms that may provide health benefits to the individual when consumed in sufficient quantities. For studies conducted on health or disease endpoints on probiotics in the United States, the Food and Administration has required those studies to be conducted as investigational new drugs. This phase I, double-blinded, randomized, controlled safety study represents the first requirement of this pathway.

Lactobacillus reuteri DSM 17938 for managing infant colic: protocol for an individual participant data meta-analysis.

Introduction: Infant colic, or excessive crying of unknown cause in infants less than 3 months old, is common and burdensome. Its aetiology is undetermined, and consensus on its management is still lacking. Recent studies suggest a possible link between infant colic and gut microbiota, indicating probiotics to be a promising treatment.

Energy capacity model for nurses: the impact of relaxation and restoration.

Objective: This study assessed the effect of stress management techniques and a restoration room on energy renewal of nurses.

Background: Nursing stress is linked to increased turnover, decreased well-being, and decreased decision-making capabilities. Energy renewal may be an effective method of addressing stress-induced exhaustion and its negative effects.

Hope floats: an orthopaedic tip sheet for float pool nurses.

A common method to address staffing shortages is the use of float nurses. This short-term resolution is not without its issues. When float nurses are unfamiliar with the assigned patient population or when there is little time for unit orientation, unnecessary anxiety and undue stress can affect the staff, healthcare providers, and, most importantly, the patients.

Assessing the safe resumption of antihypertensive medications following total hip or knee arthroplasty surgery.

Purpose: This exploratory, retrospective study aimed at examining whether patients experience orthostatic hypotension unnecessarily when antihypertensive medication(s) is simultaneously resumed following total joint replacement surgery.

Sample: The study sample consisted of 285 patients who underwent either total knee or total hip surgery and had a dual medical diagnosis of hypertension requiring treatment with more than 1 type of antihypertensive medication.

Method: Medical record reviews of all patients admitted to the orthopaedic unit from March 1, 2006, through June 30, 2006, at University of Pittsburgh Medical Center were analyzed to determine whether patients experienced any hypotensive event within 48 hr of their total joint replacement surgery following the resumption of their antihypertensive medications.

Doripenem: a new addition to the carbapenem class of antimicrobials.

Doripenem (DPM) is the newest antimicrobial in the carbapenem class. It is a broad spectrum agent with activity against gram-positive, gram-negative and anaerobic bacteria. in vitro Susceptibility testing has demonstrated potent activity for many drug resistant gram-negative pathogens including some that are resistant to imipenem and meropenem.

Establishing the role of tigecycline in an era of antimicrobial resistance.

Tigecycline is a glycylcycline antibacterial agent derived from minocycline with a broad spectrum of activity. Like tetracycline agents, it inhibits bacterial protein synthesis but is able to bind to target sites with higher affinity and overcome tetracycline-resistance mechanisms due to structural modifications. The safety and efficacy of tigecycline has been demonstrated in clinical trials for complicated intra-abdominal and complicated skin and skin-structure infections.

Assessing statistical analyses of clinical trials: primer in statistical methods for thoracic surgeons.

Each year there are many randomized controlled trials published for thoracic surgeons. To apply the results of these articles to their patients, surgeons need to have an understanding of the criteria for assessing the validity of these articles. They need to be able to recognize both methodological and statistical flaws a study may have.

Introducing handheld computing into a residency program: preliminary results from qualitative and quantitative inquiry.

Although published reports describe specific handheld computer applications in medical training, we know very little yet about how, and how well, handheld computing fits into the spectrum of information resources available for patient care and physician training. This paper reports preliminary quantitative and qualitative results from an evaluation study designed to track changes in computer usage patterns and computer-related attitudes before and after introduction of handheld computing. Pre-implementation differences between residents and faculty s usage patterns are interpreted in terms of a "work role" construct.