Measuring the One Health impacts associated with creating access to veterinary care before and during the COVID-19 pandemic.

Integrating community perceptions into One Health assessments is critical to understanding the structural barriers that create disproportionate health outcomes for community members, their pets, and the ecosystems that encompass them, particularly in historically marginalized and under-resourced communities. The validated One Health Community Assessment (OHCA) survey instrument was used to evaluate the associated impacts of The Humane Society of the United States' Pets for Life (PFL) programming on communities' perceptions of One Health. This evaluation took place across two phases, totaling four years.

Stereotactic Cardiac Radiotherapy for Refractory Ventricular Tachycardia in Structural Heart Disease Patients: A Systematic Review.

Background: Among patients with structural heart disease with ventricular tachycardia (VT) refractory to medical therapy and catheter ablation, cardiac stereotactic body radiotherapy (SBRT) is a paradigm-changing treatment option.

Aims: To assess the efficacy of cardiac SBRT in refractory VT by comparing the rates of VT episodes, anti-tachycardia pacing (ATP) therapies, and implantable cardioverter-defibrillator (ICD) shocks post-SBRT with pre-SBRT.

Methods: We performed a comprehensive literature search and included all clinical studies reporting outcomes on cardiac SBRT for VT.

Proteomic Analysis of Biological Fluids.

Biological fluids are proteinaceous liquids or suspensions released through different body orifices or through penetration of the skin. These fluids are the result of multiple tissues and cell types and contain extensive, highly complex, and dynamic protein populations that reflect both the transcriptional program of the originating cells and a record of the individual's health status. Body fluids are readily accessible to clinicians and researchers, and as such proteomic analyses are an important component of clinical studies, fertility studies, oral health studies, and forensic investigations.

Cellular Uptake of Tau Aggregates Triggers Disulfide Bond Formation in Four-Repeat Tau Monomers.

Oxidative stress is an important driver of aging and has been linked to numerous neurodegenerative disorders, including Alzheimer's disease. A key pathological hallmark of Alzheimer's are filamentous inclusions made of the microtubule associated protein Tau. Based on alternative splicing, Tau protein can feature either three or four microtubule binding repeats.

Movement Pattern Biofeedback Training After Total Knee Arthroplasty: A Randomized Controlled Trial.

Objective: Habitual movement compensations, such as decreased surgical peak knee extension moments (pKEM), persist years after total knee arthroplasty (TKA), are linked to poorer recovery, and may influence contralateral osteoarthritis progression. The purpose of this randomized clinical trial was to determine if a movement training program (MOVE) improves movement quality and recovery after TKA compared to a standardized rehabilitation program without movement training (CONTROL).

Methods: One hundred thirty-eight individuals were randomized to either MOVE or CONTROL groups after TKA.

Ushering a Witness: A Psychosocial Theory of Maternal Intrafamily Trauma Communication in the Refugee Family System.

The ways that families communicate about traumatic experiences is a critical social process. Intrafamily trauma communication encompasses approaches through which family members share and respond to difficult past experiences. We examined the embedded communication processes and actions of war-affected Karen maternal caregivers living post-resettlement in the United States, as they described disclosures of torture and war trauma experiences to their children.

Rumination induction task in fMRI: Effects of rumination focused cognitive behavioral therapy and stability in youth.

Background: Rumination is implicated in the onset and maintenance of major depressive disorder (MDD). Rumination-Focused Cognitive Behavioral Therapy (RF-CBT) effectively targets rumination and may change resting-state brain connectivity and change in activation during a rumination induction task (RIT) post-intervention predicts depressive symptoms two years later. We examined brain activation changes during an RIT in adolescents with remitted MDD following RF-CBT and evaluated RIT reliability (or stability) during treatment as usual (TAU).

Proteomic analysis of the sponge Aggregation Factor implicates an ancient toolkit for allorecognition and adhesion in animals.

The discovery that sponges (Porifera) can fully regenerate from aggregates of dissociated cells launched them as one of the earliest experimental models to study the evolution of cell adhesion and allorecognition in animals. This process depends on an extracellular glycoprotein complex called the Aggregation Factor (AF), which is composed of proteins thought to be unique to sponges. We used quantitative proteomics to identify additional AF components and interacting proteins in the classical model, , and compared them to proteins involved in cell interactions in Bilateria.

Molecular Insights into the Regulation of GNPTAB by TMEM251.

In vertebrates, newly synthesized lysosomal enzymes traffick to lysosomes through the mannose-6-phosphate (M6P) pathway. The Golgi membrane protein TMEM251 was recently discovered to regulate lysosome biogenesis by controlling the level of GlcNAc-1-phosphotransferase (GNPT). However, its precise function remained unclear.

Associations among PTSD symptoms, fear of emotion, and couple communication difficulties: A between-person dyadic analysis.

This study investigated between-person associations among PTSD symptoms, fear of emotion, and perceived couple communication difficulties in a dyadic context among 64 trauma-exposed, mixed gender community couples (N = 128 individuals) using the Actor-Partner Interdependence Mediation Model. Individuals with higher PTSD symptoms endorsed greater fear of their emotions (β = .72; β = .

Having more resilience factors only gets you so far in the context of neighborhood disadvantage: understanding differential predictors of internalizing symptoms and body mass index in youth with spina bifida.

Objective: The primary aim of this study was to determine if neighborhood disadvantage predicted internalizing symptoms and body mass index (BMI) in youth with spina bifida (SB), while accounting for several sociodemographic factors. We also explored whether resilience factors helped explain associations between neighborhood disadvantage and internalizing symptoms or neighborhood disadvantage and BMI.

Methods: Participants (n = 69, Mage=14.

An initial randomized controlled trial of a Combined Medication and Behavioral Activation Treatment (CoMBAT) for people with opioid use disorder.

Introduction: Opioid use disorder is a chronic, relapsing disease and a major source of morbidity and mortality in the U.S. Medications for opioid use disorder (MOUD) have been shown to reduce opioid use; however, MOUD maintenance is often suboptimal.

Effects of a video intervention and ethnocultural empathy on racial color-blindness, White empathy, and willingness to confront White privilege.

Objectives: This purpose of this study was to examine (a) the effects of a video intervention on decreasing racial color-blindness, increasing White people's empathy toward racism (i.e., White empathy), and increasing willingness to confront White privilege; and (b) whether ethnocultural empathy moderated the effect of this intervention on these two outcomes.

Visible Light Triggerable CO Releasing Micelles.

Carbon monoxide (CO), along with nitric oxide and hydrogen sulfide, is one of a trinity of known gasotransmitters, or endogenously produced gaseous molecules that signal and regulate a panoply of physiological functions. CO releasing molecules (CORMs) are chemical tools that enable the study and application of this ephemeral gas, that, ideally, release CO on-demand when externally stimulated. Surveying the available triggers, photolysis is potentially advantageous: It is contactless and grants practitioners unparalleled spatial and temporal control.

Knowledge of and access to contraceptive information and services among teenagers with child welfare involvement: A descriptive study across the transition to high school.

Despite disproportionate rates of childbearing among youth with child welfare involvement, few studies have examined whether this population receives contraceptive information and knows how to access services. This longitudinal study examines responses from 245 youth with child welfare involvement (i.e.

Move or Not to Move: Factors of Mind-Body Practice Engagement in a Population-Based Study.

Mind-body practices (MBPs), which include seated- (meditation) and movement-based practices (yoga, Tai Chi, ), have grown increasingly popular in the United States for improving mental and physical wellness. While literature has identified socioeconomic and health-related factors related to seated- and movement-MBP engagement separately, no studies have explored the factors associated with combined-MBP use. This study accordingly used Anderson's behavioral model of health service utilization to explore sociodemographic and health-related factors associated with seated-, movement-, and combined-MBP engagement among a representative adult sample in the 2017 National Health Interview Survey.

Using Artificial Intelligence to Identify Effective Components of Computer-Assisted Cognitive Behavioural Therapy.

Although clinician-supported computer-assisted cognitive-behaviour therapy (CCBT) is well established as an effective treatment for depression and anxiety, less is known about the specific interventions used during coaching sessions that contribute to outcomes. The current study used artificial intelligence (AI) to identify specific components of clinician-supported CCBT and correlated those scores with therapy outcomes. Data from a randomized clinical trial comparing clinician-supported CCBT with treatment as usual in a primary care setting were utilized.

Committing to emotion regulation: Factors impacting the choice to implement a reappraisal after its generation.

Cognitive reappraisal, changing the way one thinks about an emotional event, is one of the most effective and extensively studied emotion regulation strategies. Previous research has dissociated the generation of reappraisals (i.e.