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Molecular and Genetic Characterization of Colicinogenic Strains Active against Shiga Toxin-Producing O157:H7.
Foods
July 2023
Laboratorio de Inmunoquímica y Biotecnología, Centro de Investigación Veterinaria de Tandil (CIVETAN), CONICET, CICPBA, Facultad de Ciencias Veterinarias, UNICEN-Campus Universitario, Tandil B7000, Argentina.
The objective of this work was to molecularly and genotypically characterize and test the inhibitory activity of six colicinogenic strains (ColEc) and their partially purified colicins against STEC O157:H7 isolated from clinical human cases. Inhibition tests demonstrated the activity of these strains and their colicins against STEC O157:H7. By PCR it was possible to detect colicins Ia, E7, and B and microcins M, H47, C7, and J25.
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