Progress and Challenges in Integrating Nutritional Care into Oncology Practice: Results from a National Survey on Behalf of the NutriOnc Research Group.

Introduction: Nutritional care is a cornerstone of cancer treatment, with the potential to significantly improve patient outcomes by addressing malnutrition and enhancing recovery. Despite growing awareness, the integration of evidence-based nutritional strategies into oncology remains inconsistent. Following a 2020 survey that highlighted critical gaps, the NutriOnc Research Group launched targeted initiatives to raise awareness and improve practices.

Crystal Plasticity Simulation of Cyclic Behaviors of AZ31B Magnesium Alloys via a Modified Dislocation-Twinning-Detwinning Model.

In this study, a probabilistic model within the dislotwin constitutive framework of DAMASK (the Düsseldorf Advanced Material Simulation Kit) was established to describe the cyclic loading behaviors of AZ31B magnesium alloys. Considering the detwinning procedure within the twinned region, this newly developed dislocation-twinning-detwinning model was employed to accurately simulate stress-strain behaviors of AZ31B magnesium alloys throughout tension-compression-tension (T-C-T) cycle loading. The investigations revealed that the reduction in yield stress during the reverse loading process was attributed to the active operation of twinning and detwinning modes.

Resonant and Non-Resonant Impurity States Related to GaAs/AlGaAs Quantum Well Sub-Bands.

The energy positions and wave function shapes of the ground and excited states of impurities, including resonance states, are studied using the expansion of the impurity wave function in basis functions. The structures under study are rectangular GaAs/AlGaAs quantum wells with four different widths. In all cases, the impurity binding energy (relative to the corresponding sub-band) has a maximum at or near the center of the quantum well, decreases as the heterointerface is approached, and apparently has a limit of 0 if the impurity moves deeper into the barrier.

Multilateral Use of Dandelion in Folk Medicine of Central-Eastern Europe.

Background: Dandelion ( sect. , also referred to as F.H.

Social Relationships of Captive Bachelor Przewalski's Horses and Their Effect on Daily Activity and Space Use.

Understanding social relationships in at-risk species held in captivity is vital for their welfare and potential reintroduction. In social species like the Przewalski's horse (), daily time allocation and space use may be influenced by social structure and, in turn, reflect welfare. Here, we identify social relationships, time budgets, and spatial distribution of a group of nine older (aged 6-21 years) male Przewalski's horses living in a non-breeding (bachelor) group.

Sr and Cs distribution in Chornobyl forests: 30 years after the nuclear accident.

The primary aim of this study was to quantify patterns in the distribution of Sr and Cs activity in pine (Pinus sylvestris L.: 18 sites) and birch (Betula pendula Roth.: 2 sites) forests within the Chornobyl exclusion zone, 30 years after the Chornobyl nuclear power plant (NPP) accident (1986).

Across the firewall: Foreign media's role in shaping Chinese social media narratives on the Russo-Ukrainian War.

There is a widespread perception that China's digital censorship distances its people from the global internet, and the Chinese Communist Party, through state-controlled media, is the main gatekeeper of information about foreign affairs. Our analysis of narratives about the Russo-Ukrainian War circulating on the Chinese social media platform Weibo challenges this view. Comparing narratives on Weibo with 8.

Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature.

Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of -mutated patients, we aimed at characterizing the immunopathology associated with each phenotype. Although defective T and B cell development is common to all phenotypes, patients with hypomorphic variants can generate T and B cells with signatures of immune dysregulation and produce autoantibodies to a broad range of self-antigens, including type I interferons.

Psychogenetic Features of Heredity and Pathology.

The purpose of this study is to provide an in-depth examination of the complex aspects of hereditary and pathological conditions arising based on psychogenetic factors, in particular, the disclosure of elements that determine the causes of their appearance. The following methods were used in the study: analytical, typological approaches, and generalization. It was found that genetic inheritance plays a significant role in the occurrence of autism spectrum disorders, bipolar disorder, schizophrenia, and other pathologies.

Current status and trend of global research on the pharmacological effects of emodin family: bibliometric study and visual analysis.

Emodin, as a natural active ingredient, has shown great application potential in the fields of medicine, food and cosmetics due to its unique pharmacological effects, such as anti-inflammatory, antioxidant, anti-cancer, etc. In recent years, with the development of science and technology and the increase of people's demand for natural medicine, emodin research has been paid more and more attention by the global scientific research community. The bibliometric analysis of emodin and the construction of knowledge map are still blank.

Predicting Live Weight for Female Rabbits of Meat Crosses From Body Measurements Using LightGBM, XGBoost and Support Vector Machine Algorithms.

Prediction of body weight (BW) using biometric measurements is an important tool especially for animal welfare and automatic phenotyping tools that needs mathematical models. In this study, it was aimed to predict the BW using body length (BL), chest girth (CG) and width of the waist (WW) for rabbits of the maternal form of Hyla NG. The standard rabbit-raising practices were applied for the animals.

Comment on "Dolphin and porpoise detections by the F-POD are not independent: Implications for sympatric species monitoring" [JASA Express Lett. 4, 031202 (2024)].

Dolphin and porpoise detections by the F-POD are not independent: Implications for sympatric species monitoring, Cosentino, Marcolin, Griffiths, Sánchez-Camí, and Tougaard [(2024). JASA Express Lett. 4, 031202] address a significant issue, the reliability of the discrimination of dolphins and porpoises in recordings of their acoustic clicks by F-POD loggers, but unfortunately present a misleading interpretation of the process and results.

Vidofludimus Calcium in Patients with Moderate-to-Severe Ulcerative Colitis: A Randomized, Placebo-Controlled, Phase 2 Trial.

Introduction: Vidofludimus calcium (VidoCa) is a dihydroorotate dehydrogenase (DHODH) inhibitor that demonstrated efficacy in immune-related diseases. This study assessed the safety and efficacy of VidoCa in patients with active ulcerative colitis (UC).

Methods: This placebo-controlled, phase 2 trial randomized adults with moderate-severe UC to receive once-daily VidoCa (10, 30, or 45 mg) or placebo for 10 weeks (induction); patients with symptomatic remission were re-randomized to VidoCa 10, 30 mg, or placebo once-daily for an additional 40 weeks (maintenance).

The impact of war on people with type 2 diabetes in Ukraine: a survey study.

Background: Although the number of studies reporting war-induced effects on the health of the Ukrainian population has been growing, there are still little data on assessing patients with type 2 diabetes (T2D) during the war. This study aimed to evaluate the impact of war on T2D patients' health to define key risk factors promoting disease progression.

Methods: A survey covering various aspects of T2D patients' experience and glycemic control data was conducted from June 2022 to February 2024.

Phytotoxicity of the aqueous solutions of some dishwashing detergents for dishwashers with phosphonates and without phosphates.

The influx of insufficiently purified or untreated domestic wastewater into aquatic ecosystems raises the question of the production of environmentally friendly detergents. The purpose of this work was to investigate the toxicity of phosphonate-containing and phosphate-free dishwashing detergents for dishwashers according to the phytotest with a garden cress ( L.).

Coupling mechanisms of plasmon resonance and Bi3+ emission in YAG: Bi, Ce, Yb epitaxial films at low temperatures.

This paper is devoted to the investigation of the plasmonic effect of metal nanoparticles (NPs) formed on the surface of the YAG: Bi, Ce, Yb phosphors in a temperature range between 4 and 300 K. Combination of a thin conversion layer with silver plasmonic nanostructures leads to increase of sensitizer absorption and emission efficiency. Enhancement of Bi luminescence in YAG epitaxial films with Ag NPs was observed upon cooling the samples below 200 K.

Silver nanoparticles coated with metabolites of Pseudomonas sp. N5.12 inhibit bacterial pathogens and fungal phytopathogens.

The synthesis of nanomaterials from PGPB is an exciting approach and it's often used in agriculture as nano-fertilizers and nano-pesticides. The present study reports a new approach to biosynthesis of silver nanoparticles (AgNP), using bacterial metabolites as agents to reduce Ag, which will remain as coating agents able to prevent microbial growth. Silver NP were biosynthesized using the bacterial metabolites produced by the beneficial strain Pseudomonas sp.

Smart furniture using radar technology for cardiac health monitoring.

The integration of radar technology into smart furniture represents a practical approach to health monitoring, circumventing the concerns regarding user convenience and privacy often encountered by conventional smart home systems. Radar technology's inherent non-contact methodology, privacy-preserving features, adaptability to diverse environmental conditions, and high precision characteristics collectively establish it a compelling alternative for comprehensive health monitoring within domestic environments. In this paper, we introduce a millimeter (mm)-wave radar system positioned strategically behind a seat, featuring an algorithm capable of identifying unique cardiac waveform patterns for healthy subjects.

Bacteriophage derived dsRNA induces polarized activation of alveolar macrophages from Balb/c and C57Bl/6 mice in vitro in sex- and age-dependent manner.

Bacteriophage-derived dsRNA (bp-dsRNA), also known as Larifan, is a poly-functional and wide-spectrum antiviral medication with potent interferonogenic activity. In the lungs of golden Syrian hamsters infected with SARS-CoV-2, Larifan substantially reduces viral load and decreases infection-induced pathological lesion severity. Alveolar macrophages (AM) are key sentinel cells in the lung, which play an important role in antiviral innate immune responses and, at the same time, can trigger infection-associated hyper-inflammatory response.

New Hydrazone Derivatives Based on Pyrazolopyridothiazine Core as Cytotoxic Agents to Colon Cancers: Design, Synthesis, Biological Evaluation, and Molecular Modeling.

In this research, a series of novel hydrazone derivatives based on pyrazolopyridothiazinylacetohydrazide were designed, synthesized, and evaluated for their in vitro cytotoxic potency on several human colon cancer cells (HTC116, HT-29, and LoVo). After MTT and SRB assays four of the most active derivatives: hydrazide GH and hydrazones GH7, GH8, and GH11, were chosen for further investigation. Hydrazone GH11 had the highest cytotoxic activity (IC50 values of c.

CT-P39 Compared With Reference Omalizumab in Chronic Spontaneous Urticaria: Results From a Double-Blind, Randomized, Active-Controlled, Phase 3 Study.

Background: This study compared the therapeutic equivalence of CT-P39 (an omalizumab biosimilar) and EU-approved reference omalizumab (ref-OMA) in patients with chronic spontaneous urticaria.

Methods: This double-blind, randomized, active-controlled Phase 3 study (NCT04426890) included two 12-week treatment periods (TPs). In TP1, patients received CT-P39 300 mg, ref-OMA 300 mg, CT-P39 150 mg, or ref-OMA 150 mg.

Gonadal function and pathology in 17beta-HSD 3 and 5alpha-reductase deficiency.

Objective: 17β-Hydroxysteroid dehydrogenase 3 deficiency (17β-HSDD) and 5α-reductase type 2 deficiency (5α-RD) are rare 46,XY differences of sex development (DSD). This study aims to enlarge the limited knowledge on long-term gonadal function and gonadal pathology in these conditions.

Design: Retrospective multicentre cohort study.