2 results match your criteria: "UK. Electronic address: sfinfer@georgeinstitute.org.au.[Affiliation]"

Balanced crystalloids versus saline for critically ill patients (BEST-Living): a systematic review and individual patient data meta-analysis.

Lancet Respir Med

March 2024

The George Institute for Global Health, Sydney, NSW, Australia; University of New South Wales, Sydney, NSW, Australia; School of Public Health, Imperial College London, London, UK. Electronic address:

Background: The effect of balanced crystalloids compared with that of saline in critically ill patients overall and in specific subgroups is unclear. We aimed to assess whether use of balanced solutions, compared with 0·9% sodium chloride (saline), decreased in-hospital mortality in adult patients in intensive care units (ICUs).

Methods: For this systematic review and individual patient data meta-analysis, we searched PubMed, Embase, and CENTRAL databases from inception until March 1, 2022 (updated Sept 1, 2023) for individually randomised and cluster-randomised trials comparing balanced solutions with saline for adult patients in the ICU.

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Sepsis 3 from the perspective of clinicians and quality improvement initiatives.

J Crit Care

August 2017

Global Sepsis Alliance Quality Improvement Committee, Paul-Schneider-Str. 2, 07747 Jena, Germany. Electronic address:

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