1 results match your criteria: "UK University Department of Anaesthesia and Pain Management[Affiliation]"
Identification of nociceptin in human cerebrospinal fluid: comparison of levels in pain and non-pain states.
Pain
October 1998
NHS Division of Anaesthesia, Leicester Royal Infirmary, Leicester, LE1 5WW, UK Parke-Davis Neuroscience Research Centre, Cambridge University Forvie Site, Robinson Way, Cambridge, CB2 2QB, UK University Department of Anaesthesia and Pain Management, Leicester Royal Infirmary, Leicester, LE 1 5WW, UK.
We have measured plasma and cerebrospinal fluid (CSF) concentrations of nociceptin, the endogenous agonist of the orphan opioid receptor-like receptor (ORL-1). We studied two groups of ten patients presenting for elective Caesarean section (Group E) or in established labour and requiring combined spinal epidural anaesthesia for pain relief (Group L). Nociceptin was identified in all CSF samples with mean +/- SD concentrations of 52.
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