4 results match your criteria: "UK Fetal Medicine Centre[Affiliation]"
Intrahepatic cholestasis of pregnancy.
BMJ
April 2016
Centre for Women's and New-born Health, Institute of Metabolism and Systems Research, College of Medical Sciences, University of Birmingham, Birmingham, B15 2TT, UK Fetal Medicine Centre, Birmingham Women's Foundation Trust, Birmingham, UK.
Prenatal therapy in transient abnormal myelopoiesis: a systematic review.
Arch Dis Child Fetal Neonatal Ed
January 2016
Centre for Women's & Children's Health, College of Medical & Dental Sciences, University of Birmingham, Birmingham, UK Fetal Medicine Centre, Birmingham Women's Foundation Trust, Edgbaston, Birmingham, UK.
Objective: To systematically review current evidence regarding prenatal diagnosis and management of transient abnormal myelopoiesis (TAM) in fetuses with trisomy 21. A novel case of GATA1-positive TAM, in which following serial in utero blood transfusion clinical improvement and postnatal remission were observed, is included.
Search Strategy And Data Collection: A systematic search of electronic databases (inception to October 2014) and reference lists, hand-searching of journals and expert contact.
The challenges of interventional trials in fetal therapy.
Arch Dis Child Fetal Neonatal Ed
November 2014
Centre for Women's & Children Health and the School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK Fetal Medicine Centre, Birmingham Women's Hospital NHS Foundation Trust, Birmingham, UK.
Exome sequencing improves genetic diagnosis of structural fetal abnormalities revealed by ultrasound.
Hum Mol Genet
June 2014
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
The genetic etiology of non-aneuploid fetal structural abnormalities is typically investigated by karyotyping and array-based detection of microscopically detectable rearrangements, and submicroscopic copy-number variants (CNVs), which collectively yield a pathogenic finding in up to 10% of cases. We propose that exome sequencing may substantially increase the identification of underlying etiologies. We performed exome sequencing on a cohort of 30 non-aneuploid fetuses and neonates (along with their parents) with diverse structural abnormalities first identified by prenatal ultrasound.
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