Implementing and Delivering Culturally Centred Pharmacy Services Tailored to Ethnically Minoritised Populations: A Qualitative Systematic Review and Meta-Ethnography.

Introduction: Health inequities disproportionately affect people from ethnic minority communities and require a comprehensive effort across healthcare disciplines to tackle them. Ethnically minoritised populations continue to be underserved, despite the growing awareness of the detrimental link between ethnicity and poorer health- and medication-outcomes. Pharmacy has been recognised as an accessible and inclusive healthcare setting, with the ability to meet diverse patient needs.

On-Demand Sintering of Gold Nanoparticles via Controlled Removal of o-Nitrobenzyl Thiol Ligands Under Record-Low Power for Conductive Patterns.

Metal nanoparticles-based nanoinks have shown potential for fabricating metallic components essential to the realization of innovative 3D-printed electronic devices. However, fabricating metallic patterns on flexible, heat-sensitive substrates remains challenging due to high temperature and high energy sources, such as intense pulsed light (IPL), involved in the sintering process. Here an efficient sintering method is presented using ultralow power UV by leveraging the photocleavable ligand, o-nitrobenzyl thiol (NT), - functionalized gold nanoparticles (AuNPs).

Glucagon-Like Peptide-1 Links Ingestion, Homeostasis, and the Heart.

Glucagon-like peptide-1 (GLP-1), a hormone released from enteroendocrine cells in the distal small and large intestines in response to nutrients and other stimuli, not only controls eating and insulin release, but is also involved in drinking control as well as renal and cardiovascular functions. Moreover, GLP-1 functions as a central nervous system peptide transmitter, produced by preproglucagon (PPG) neurons in the hindbrain. Intestinal GLP-1 inhibits eating by activating vagal sensory neurons directly, via GLP-1 receptors (GLP-1Rs), but presumably also indirectly, by triggering the release of serotonin from enterochromaffin cells.

Xenotransplantation as a business solution to the organ shortage.

Xenotransplantation has the potential to alter the U.S. transplant system in profound ways.

Actual weight loss trajectories after bariatric surgery compared with the SOPHIA prediction tool: An observational comparison study.

Aims: Estimation of post-bariatric surgery weight loss is important for informed clinical decisions, yet existing predictive models lack accuracy and reliability. We assessed the effectiveness of the validated Stratification of Obesity Phenotypes to Optimize Future Therapy (SOPHIA) bariatric weight trajectory prediction tool in our patient population.

Materials And Methods: We conducted a retrospective study of 178 adults who underwent bariatric surgery over a 3-year period.

Inter-Laboratory Validation of Nodal/Paranodal Antibody Testing.

Background And Aims: Reliable detection of antibodies against nodal targets is vital for the diagnosis of autoimmune nodopathies. The performance characteristics of recently developed in-house assays are unknown. We compared testing at four centres.

How do people with a history of sexual abuse experience talking therapies for sexual trauma? A systematic review of qualitative findings.

Objectives: This systematic review investigated the qualitative experiences of sexual abuse survivors in talking therapy treatments with respect to the helpful and hindering aspects of therapy.

Methods: Searches were conducted on five databases; PubMed, Web of Science, PyscInfo, PsycArticles and PsycExtra and through searching reference lists. Papers were included where they provided qualitative primary data of client experiences of therapy, did not involve specialist clinical populations and were written in English.

How prototypical are we compared to them? The role of the group relative prototypicality in explaining the path from intergroup contact to collective action.

In two cross-sectional and two experimental studies across both advantaged and disadvantaged group members (N = 1980 from two national contexts, UK and Italy), we explored if perceptions of group relative prototypicality may explain the association of positive and negative contact with collective action. Specifically, across studies, we investigated subgroup relative prototypicality with respect to four different common identities (national, supranational, based on humanity, humanity values). In Studies 1-2, among advantaged group members, positive contact was positively associated with collective action intentions via greater relative prototypicality of disadvantaged groups; in Study 2, we also found that negative contact was negatively associated with collective action intentions via decreased relative prototypicality of disadvantaged groups.

TR(Acking) Individuals Down: Exploring the Effect of Temporal Resolution in Resting-State Functional MRI Fingerprinting.

Functional brain fingerprinting has emerged as an influential tool to quantify reliability in neuroimaging studies and to identify cognitive biomarkers in both healthy and clinical populations. Recent studies have revealed that brain fingerprints reside in the timescale-specific functional connectivity of particular brain regions. However, the impact of the acquisition's temporal resolution on fingerprinting remains unclear.

Effects of agronomical practices on potato growth, nutritional profile, and suitability for frying.

Background: This study investigated the effect of sulfur nutrition, basalt rock aggregate (BA) application, with a carbon capture function, and speed breeding under light-emitting diode (LED) light, on the nutritional profile of potatoes and acrylamide formation in crisp production.

Results: Taurus potatoes grown with sulfur showed reduced glucose, sucrose, and total amino acids, and increased asparagine. No difference in acrylamide content was observed in crisps from Taurus and Lady Claire cultivars, with either sulfur or BA application.

Relationships of maternal hemodynamics in the third trimester with fetal umbilical artery doppler indices, estimated fetal weight and birth weight in women with and without congenital heart disease.

Objective: To compare differences in maternal hemodynamics, measured non-invasively by impedance cardiography and mean arterial blood pressure (MAP)-at rest and with high-intensity exercise-between pregnant women with corrected congenital heart disease (CHD) and low-risk (LR) pregnant controls, and to correlate these findings with umbilical artery Doppler in the third trimester, estimated fetal weight (EFW) and birth weight (BW).

Methods: Prospective longitudinal study with hemodynamic exercise studies and fetal ultrasound between 30 and 34 weeks' gestation. Approval was obtained from London South East Research Ethics Committee.

Osteology of the appendicular skeleton of Bagualia alba (Dinosauria, Eusauropoda) from the Lower Jurassic of Patagonia and the macroevolutionary history of early eusauropods.

Since their origin, sauropodomorphs have undergone numerous anatomical changes from small and bipedal early sauropodomorphs towards massive-bodied and quadrupedal sauropods. However, the timing of these changes in the evolution of the group is unclear. Here, we describe the appendicular skeleton of the early diverging eusauropod Bagualia alba from the late Early Jurassic of Patagonia, Argentina, and conduct a morphological disparity analysis based on a phylogenetic dataset of Sauropoda.

Morphological Criteria for Staging Near-Hatching Embryos of the Domesticated Mallard (Anas platyrhynchos) and Swan Goose (Anser cygnoides).

Studying avian embryology necessitates reliable and precise staging tables-descriptions of embryonic features appearing during development that are used to approximate the extent of embryonic development from fertilisation to hatching. Staging tables for waterfowl (Anseriformes) have previously been established based on morphological features from fertilisation to approximately 10 days before hatching. Embryonic changes over the final 10 days of pre-hatching development have also been documented and proposed as useful staging criteria.

Simultaneous Isotropic Omnidirectional Hypersensitive Strain Sensing and Deep Learning-Assisted Direction Recognition in a Biomimetic Stretchable Device.

Omnidirectional strain sensing and direction recognition ability are features of the human tactile sense, essential to address the intricate and dynamic requirements of real-world applications. Most of the current strain sensors work by converting uniaxial strain into electrical signals, which restricts their use in environments with multiaxial strain. Here, the first device with simultaneous isotropic omnidirectional hypersensitive strain sensing and direction recognition (IOHSDR) capabilities is introduced.

International multistakeholder consensus statement on post-publication integrity issues in randomized clinical trials by Cairo Consensus Group.

The number of retractions of randomized clinical trials (RCTs) following post-publication allegations of misconduct is increasing. To address this issue, we aimed to establish an international multistakeholder consensus on post-publication integrity concerns related to RCTs. After prospective registration (https://osf.

Native state structural and chemical characterisation of Pickering emulsions: A cryo-electron microscopy study.

Transmission electron microscopy can be used for the characterisation of a wide range of thin specimens, but soft matter and aqueous samples such as gels, nanoparticle dispersions, and emulsions will dry out and collapse under the microscope vacuum, therefore losing information on their native state and ultimately limiting the understanding of the sample. This study examines commonly used techniques in transmission electron microscopy when applied to the characterisation of cryogenically frozen Pickering emulsion samples. Oil-in-water Pickering emulsions stabilised by 3 to 5 nm platinum nanoparticles were cryogenically frozen by plunge-freezing into liquid ethane to retain the native structure of the system without inducing crystallisation of the droplet oil cores.

Psoriasis in People With Skin of Color: An Evidence-Based Update.

Variations in epidemiology, pathophysiology, genetics, clinical presentation, management, quality of life (QoL) impact, and access to care and research exist globally across the spectrum of individuals with psoriasis. This article aims to provide an evidence-based update on the characteristics of psoriasis in individuals with skin of color (SOC), a population in which psoriasis data have historically been limited. A literature search was conducted from January 2018 until August 2023 in Pubmed/MEDLINE/Cochrane Library and identified studies with I-III level of evidence using Oxford Centre for Evidence-Based Medicine recommendations.

Direct and indirect genetic effects on early neurodevelopmental traits.

Background: Neurodevelopmental conditions are highly heritable. Recent studies have shown that genomic heritability estimates can be confounded by genetic effects mediated via the environment (indirect genetic effects). However, the relative importance of direct versus indirect genetic effects on early variability in traits related to neurodevelopmental conditions is unknown.

Genome-wide aggregated trans- effects analysis identifies genes encoding immune checkpoints as core genes for rheumatoid arthritis.

Objectives: The sparse effector "omnigenic" hypothesis postulates that the polygenic effects of common SNPs on a typical complex trait are mediated by trans- effects that coalesce on expression of a relatively sparse set of core genes. The objective of this study was to identify core genes for rheumatoid arthritis by testing for association of rheumatoid arthritis with genome-wide aggregated trans- effects (GATE) scores for expression of each gene as transcript in whole blood or as circulating protein levels.

Methods: GATE scores were calculated for 5400 cases and 453705 non-cases of primary rheumatoid arthritis in UK Biobank participants of European ancestry.

Integrating Humidity-Resistant and Colorimetric COF-on-MOF Sensors with Artificial Intelligence Assisted Data Analysis for Visualization of Volatile Organic Compounds Sensing.

Direct visualization and monitoring of volatile organic compounds (VOCs) sensing processes via portable colorimetric sensors are highly desired but challenging targets. The key challenge resides in the development of efficient sensing systems with high sensitivity, selectivity, humidity resistance, and profuse color change. Herein, a strategy is reported for the direct visualization of VOCs sensing by mimicking human olfactory function and integrating colorimetric COF-on-MOF sensors with artificial intelligence (AI)-assisted data analysis techniques.