Identification of ABHD6 as a lysophosphatidylserine lipase in the mammalian liver and kidneys.

Lysophosphatidylserine (lyso-PS) is a potent hormone-like signaling lysophospholipid, which regulates many facets of mammalian biology and dysregulation in its metabolism is associated with several human neurological and autoimmune diseases. Despite the physiological importance and causal relation with human pathophysiology, little is known about the metabolism of lyso-PS in tissues other than the nervous and immune systems. To address this problem, here, we attempted to identify one (or more) lipase(s) capable of degrading lyso-PS in different mammalian tissues.

Enhanced adsorption and photocatalytic degradation of tetracycline antibiotics through novel I-Bi/BiWO@MWCNTs heterostructure composite photocatalyst.

Bismuth-based photocatalysts proved to have remarkable photoactivity for antibiotic degradation from water. However, the two significant challenges of bismuth-based photocatalysts are the fast charge recombination rate and higher energy band gap. This study successfully synthesized a novel I-Bi/BiWO/MWCNTs (C-WBI) heterostructure composite photocatalysts with shorter energy band-gap and higher charge production capability through interfacial amidation linkage.

Is there an association between eye-level greenness and childhood hypertension using street view? Findings from the Seven Northeastern Cities study in China.

There is a lack of evidence regarding associations of eye-level greenness exposure with blood pressure among children. We aimed to investigate the associations between eye-level greenness of different types and pediatric blood pressure in China. From 2012 to 2013, we recruited 9354 children aged between 5 and 17 years in northeast China.

Lysoglycerophospholipid metabolism alterations associated with ambient fine particulate matter exposure: Insights into the pro-atherosclerotic effects.

The biological pathways connecting ambient fine particulate matter (PM)-induced initial adverse effects to the development of atherosclerotic cardiovascular diseases are not fully understood. We hypothesize that lysoglycerophospholipids (LysoGPLs) are pivotal mediators of atherosclerosis induced by exposure to PM. This study investigated the changes of LysoGPLs in response to PM exposure and the mediation role of LysoGPLs in the pro-atherosclerotic effects of PM exposure.

On the correction factors for small field dosimetry in 1.5T MR-linacs.

Clinical dosimetry in the presence of a 1.5T magnetic field is challenging, let alone in case small fields are involved. The scope of this study is to determine a set of relevant correction factors for a variety of MR-compatible detectors with emphasis on small fields.

Knowledge domain and frontier trends of artificial intelligence applied in solid organ transplantation: A visualization analysis.

Background: Solid organ transplantation (SOT) is vital for end-stage organ failure but faces challenges like organ shortage and rejection. Artificial intelligence (AI) offers potential to improve outcomes through better matching, success prediction, and automation. However, the evolution of AI in SOT research remains underexplored.

Detecting Xe in an atmospheric tracer experiment.

The Xcounts algorithm for calculating air concentrations of radioactive xenon isotopes (Eslinger et al., 2023) has been extended to estimate Xe in addition to Xe, Xe, Xe, and Xe. The algorithm was applied to 119 samples collected with a SAUNA Q system (Ringbom et al.

The PDC30 Chatbot-Development of a Psychoeducational Resource on Dementia Caregiving Among Family Caregivers: Mixed Methods Acceptability Study.

Background: Providing ongoing support to the increasing number of caregivers as their needs change in the long-term course of dementia is a severe challenge to any health care system. Conversational artificial intelligence (AI) operating 24/7 may help to tackle this problem.

Objective: This study describes the development of a generative AI chatbot-the PDC30 Chatbot-and evaluates its acceptability in a mixed methods study.

"Central retinal artery occlusion following scleral buckling surgery with gas insertion in a patient with sickle cell disease".

Purpose: To describe a case of central retinal artery occlusion following scleral buckling procedure combined with pneumoretinopexy in a patient with sickle cell (HbSC) retinopathy (SCR).

Methods: Scleral buckling procedure, combined with injection of 0.3 ml of 100% perfluoropropane (C3F8) gas in the vitreous, was performed without intra-operative complications under general anaesthesia as treatment of two separate macula-sparing rhegmatogenous retinal detachments secondary to round holes, involving superior and inferior retina respectively, in the right eye of a 26-year-old Afro-Caribbean female with sickle cell disease.

Sampling Mars: Geologic context and preliminary characterization of samples collected by the NASA Mars 2020 Perseverance Rover Mission.

The NASA Mars 2020 Perseverance Rover Mission has collected samples of rock, regolith, and atmosphere within the Noachian-aged Jezero Crater, once the site of a delta-lake system with a high potential for habitability and biosignature preservation. Between sols 109 and 1,088 of the mission, 27 sample tubes have been sealed, including witness tubes. Each sealed sample tube has been collected along with detailed documentation provided by the Perseverance instrument payload, preserving geological and environmental context.

Patient-Reported Outcome Scale for Allergic Rhinitis (AR-PRO): Development and Validation in China.

Background: Patient-reported outcomes (PROs) have become indispensable measures in allergic rhinitis (AR) clinical trials. However, there is currently no scale specifically designed for the Chinese population. This study aimed to develop and validate the patient-reported outcome scale for allergic rhinitis (AR-PRO) to provide a reliable tool for AR patients in China.

A Survey Study on the Current Veterinary Practice and Attitudes to Anaesthesia and Analgesia for Spay Surgery in the United Kingdom.

Background: In the United Kingdom, spay surgery is routinely performed in dogs and cats by general practitioners. Data from a decade ago showed that, despite an increased attentiveness of veterinarians to peri-operative pain compared to the past, analgesia could be further improved.

Objectives: To investigate the current veterinary practice and attitude towards anaesthesia and analgesia for spay surgery in the United Kingdom.

Application of X-ray diffraction with Rietveld refinement to quantify mineral composition including crystalline silica in respirable dust.

This study aimed to test the use of Rietveld refinement on respirable aerosol samples to determine the phase of respirable crystalline silica (RCS) and other minerals. The results from the Rietveld refinement were compared to an external standard method and gravimetrical measurements. Laboratory samples consisting of α-quartz, feldspar, and calcite with variable proportions and total mass loadings were made and analyzed using the NIOSH 7500 , followed by Rietveld refinement.

Investigating the Relationship between Burnout, Workload, and Imposter Syndrome for Mental Health Nurses in the UK.

This study investigated the interrelationship between burnout, workload, and imposter syndrome among mental health nurses within the UK. Understanding their connections is crucial given the detrimental effects of these factors on workplace well-being. Despite extensive research on imposter syndrome in various healthcare professions, its exploration within nursing has been limited.

Researching gender and loneliness differently.

The majority of research on loneliness considers gender by comparing the loneliness reported by men and women. Drawing on current conceptualizations of gender and its effects, we propose alternative ways in which gender should be examined in relation to loneliness. To do so, we consider multiple gender-related factors and the role of the social environment, particularly societal ideologies about what gender is and how it should be expressed.

Exploring the relationship between medically unnecessary childhood penile circumcision and adult mental health.

There is increasing recognition of the need to address the diverse experiences of individuals subjected to medically unnecessary, non-voluntary genital cutting in childhood. This includes children with intersex traits undergoing 'normalisation' surgeries and those with anatomically normative genitalia, such as female genital cutting or male circumcision. While most research on non-therapeutic childhood penile circumcision centres on the physical risks and benefits, far less attention has been given to the potential long-term mental health impacts, particularly from a psychotherapeutic perspective.

Young adult drinking during the COVID-19 pandemic: Examining the role of anxiety sensitivity, perceived stress, and drinking motives.

Studies have shown that those high in anxiety were at increased risk for alcohol use during the COVID-19 pandemic. Tension reduction theory points to anxiety sensitivity (AS) as a potential risk factor. Drinking to cope may further increase this risk.

Whole-Genome Sequencing of Antimicrobial Resistant , a Novel Sequence Type 5655 from Retail Fish Market, Assam, India.

is a recently described species that can be differentiated from . However, in clinical settings, they are frequently misidentified as . In this study, our objective was to conduct genomic characterization and bioinformatics analysis of subsp.

Intraventricular Hemorrhage and Survival, Multimorbidity, and Neurodevelopment.

Importance: Intraventricular hemorrhage (IVH) has proven to be a challenging and enduring complication of prematurity. However, its association with neurodevelopment across the spectrum of IVH severity, independent of prematurity, and in the context of contemporary care remains uncertain.

Objective: To evaluate national trends in IVH diagnosis and the association with survival and neurodevelopmental outcomes at 2 years of age.

Association of gut microbiota and gut metabolites and adverse outcomes in biliary atresia: A longitudinal prospective study.

Background: The Kasai portoenterostomy (KPE) aims to re-establish bile flow in biliary atresia (BA); however, BA remains the commonest indication for liver transplantation in pediatrics. Gut microbiota-host interplay is increasingly associated with outcomes in chronic liver disease. This study characterized fecal microbiota and fatty acid metabolites in BA.