1,643,837 results match your criteria: "UK; Barcelona Supercomputing Center[Affiliation]"

Molecular methods such as DNA/eDNA metabarcoding have emerged as useful tools to document the biodiversity of complex communities over large spatio-temporal scales. We established an international Marine Biodiversity Observation Network (ARMS-MBON) combining standardised sampling using autonomous reef monitoring structures (ARMS) with metabarcoding for genetic monitoring of marine hard-bottom benthic communities. Here, we present the data of our first sampling campaign comprising 56 ARMS units deployed in 2018-2019 and retrieved in 2018-2020 across 15 observatories along the coasts of Europe and adjacent regions.

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MXene-Based Flexible Memory and Neuromorphic Devices.

Small

January 2025

Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, 999077, P. R. China.

As the age of the Internet of Things (IoTs) unfolds, along with the rapid advancement of artificial intelligence (AI), traditional von Neumann-based computing systems encounter significant challenges in handling vast amounts of data storage and processing. Bioinspired neuromorphic computing strategies offer a promising solution, characterized by features of in-memory computing, massively parallel processing, and event-driven operations. Compared to traditional rigid silicon-based devices, flexible neuromorphic devices are lightweight, thin, and highly stretchable, garnering considerable attention.

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Prevalence of Heritable Symbionts in Parisian Bedbugs (Hemiptera: Cimicidae).

Environ Microbiol Rep

February 2025

Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.

Like many insects, the biology of bedbugs is impacted by a range of partner heritable microbes. Three maternally inherited symbionts are recognised: Wolbachia (an obligate partner), Symbiopectobacterium purcellii strain SyClec, and Candidatus Tisiphia sp. (facultative symbionts typically present in some but not all individuals).

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We argue that while a substantial proportion of emerging adults are in post-secondary education, there is relatively little consideration of this context within research and policy around youth mental health. The unique challenges young adults face in post-secondary education overlay underlying risk factors experienced by emerging adults. While post-secondary education facilitates social mobility, it also introduces stressors such as academic demands, financial insecurity and social isolation.

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A healthy diet is a protective factor against a host of negative health outcomes. To maintain such a diet necessitates the consumption of at least 240 g of vegetables per day. However, most of the population fails to meet this threshold.

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In low and middle-income countries, addressing maternal and child nutrition needs is crucial. Prenatal multiple micronutrient supplementation (MMS) holds promise in reducing low birthweight and preterm births. Ethiopia is considering a transition from the provision of iron-folate supplementation to the provision of MMS in antenatal care, guided by WHO guidelines.

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Objective: This study investigated the impact of 2019 coronavirus disease (COVID-19) lockdowns on alcohol consumption and smoking behavior among young adults from Germany.

Methods: An online survey was completed by N = 317 young adults living in Germany. Of these, 140 (44.

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Photonic pigments, especially those based on naturally-derived building blocks like cellulose nanocrystals (CNCs), are emerging as a promising sustainable alternative to absorption-based colorants. However, the proposed manufacturing methods for CNC pigments, via either grinding films or emulsion-based production, usually require several processing steps. This limits their commercialization by increasing the costs, timescales, and environmental impacts of production.

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To critically evaluate sport nutrition services available to male and female international rugby unions. Fifteen participants, representing 16 international rugby unions, including nine female and seven male teams (one participant worked with both a female and male union), responded to an online survey. Twelve of the unions recruited were ranked in the top 10 globally by World Rugby.

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Environmentally sustainable critical care: Special issue introduction.

Nurs Crit Care

January 2025

Research, Education, Development and Innovation Department, Skaraborg Hospital Skövde, Region Västra Götaland, Skövde, Sweden.

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The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review.

Int J Dent Hyg

January 2025

Unit of Periodontology, Endodontology, and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Background: Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.

Aim: This umbrella review aims to provide clinicians with an overview of toothpaste ingredients and evidence of efficacy for a variety of oral conditions, including gum health issues, caries, dentine hypersensitivity, tooth surface loss, oral malodour and tooth whitening (staining).

Methods: The focused question for the review was 'What is the efficacy of common toothpaste active ingredients in preventing or treating oral conditions including gum health issues, caries, dentine hypersensitivity, tooth surface loss, oral malodour and tooth whitening (stain removal)?'.

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Objective: Eating disorders (ED) typically emerge in adolescence, a critical period for brain development and peer bonding. Interpersonal difficulties-particularly social anxiety-frequently co-occur with ED. Oxytocin is a neuropeptide that modulates social cognition and linked to prosocial effects.

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This study aimed to examine the acute effects of concurrent muscle strength and sport-specific endurance exercise order on immunological stress responses, metabolic response, muscular-fitness, and rating-of-perceived-exertion (RPE) in highly trained youth female judo athletes. Thirteen female participants randomly performed two concurrent training (CT) sessions; strength-endurance and endurance-strength. Immune response, metabolic response, muscular fitness (i.

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Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease that affects neurons in the brain and spinal cord, causing loss of muscle control, and eventually leads to death. Phosphorylated transactive response DNA binding protein-43 (TDP-43) is the major pathological protein in both sporadic and familial ALS, forming cytoplasmic aggregates in over 95% of cases. Of the 10-15% of ALS cases that are familial, mutations in TDP-43 represent about 5% of those with a family history.

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Psychedelic-assisted treatment for substance use disorder: A narrative systematic review.

Addiction

January 2025

Addictions Department, School of Academic Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Background And Aims: This is the first systematic review of the extant literature on all major psychedelic-assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic-assisted treatment for AUD, TUD, and SUD; to evaluate its quality; and to offer recommendations for research.

Methods: This was a prospectively registered narrative systematic review of open-label, randomised controlled trials (RCT), and observational studies of d-lysergic acid diethylamide (LSD), mescaline, psilocybin, ayahuasca, ketamine, ibogaine and 3,4-methylenedioxymethamphetamine (MDMA).

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Ammonia (NH) is esteemed for its attributes as a carbon-neutral fuel and hydrogen storage material, due to its high energy density, abundant hydrogen content, and notably higher liquefaction temperature in comparison to hydrogen gas. The primary method for the synthetic generation of NH is the Haber-Bosch process, involving rigorous conditions and resulting in significant global energy consumption and carbon dioxide emissions. To tackle energy and environmental challenges, the exploration of innovative green and sustainable technologies for NH synthesis is imperative.

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Biomarker treatment effects in two phase 3 trials of gantenerumab.

Alzheimers Dement

January 2025

Department of Radiology & Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.

Introduction: We report biomarker treatment effects in the GRADUATE I and II phase 3 studies of gantenerumab in early Alzheimer's disease (AD).

Methods: Amyloid and tau positron emission tomography (PET), volumetric magnetic resonance imaging (vMRI), cerebrospinal fluid (CSF), and plasma biomarkers used to assess gantenerumab treatment related changes on neuropathology, neurodegeneration, and neuroinflammation over 116 weeks.

Results: Gantenerumab reduced amyloid PET load, CSF biomarkers of amyloid beta (Aβ)40, total tau (t-tau), phosphorylated tau 181 (p-tau181), neurogranin, S100 calcium-binding protein B (S100B), neurofilament light (NfL), alpha-synuclein (α-syn), neuronal pentraxin-2 (NPTX2), and plasma biomarkers of t-tau, p-tau181, p-tau217, and glial fibrillary acidic protein (GFAP) while increasing plasma Aβ40, Aβ42.

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Background: Energy usage is one of the largest contributors to health care carbon emissions. By taking a strategic, targeted approach in one of the most energy-intensive units of a hospital, the potential for energy savings is real and significant.

Aim: To develop a protocol for the implementation of interventions to reduce the environmental impact of carbon emissions generated by an adult intensive care unit (AICU) in a London-based hospital setting.

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Aims: Tricyclic antidepressants (TCAs) are commonly prescribed despite no longer being a NICE-recommended first-line treatment for depression and their recognized toxicity in overdose. This study examined prescribing, mortality, hospital admissions and clinical TCA data to quantify the use and impact of TCAs in England and Wales.

Methods: Primary care prescription data for the eight TCAs currently licensed in England and Wales were analysed alongside hospital admission and mortality data relating to TCAs over the study period (January 2016-December 2020 inclusive).

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Purpose: To develop a 7T neurovascular head and neck (NVHN) coil with an extended longitudinal coverage of the brain and cervical spine, with eight transceiver (TxRx) channels and 56 receive (Rx) channels for dynamic parallel-transmit (pTx) applications.

Methods: A dual-row transceiver array with six elements in the upper row and two elements in the lower row was designed using combined electromagnetic and circuit optimization and constructed. A 56Rx array covering the brain and cervical spine was designed and combined with the transceiver array.

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Objectives: We investigated the prevalence of loneliness recorded during assessment of general hospital inpatients by older adult liaison psychiatry services and its associations with level of subsequent hospitalisation, emergency presentation and mortality.

Methods: Data were drawn from a large south London mental healthcare provider of older adult liaison psychiatry services to four acute general hospitals. The sample comprised all patients receiving assessments from these services from 2007-2017.

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Background: Fungi are ubiquitous in horses' environment. Their contribution to the pathophysiology of severe asthma (SA) is acknowledged, while controversies remain for mild-moderate asthma (MA).

Objectives: We hypothesised that fungi are a risk factor for asthma.

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Aim: To explore the experiences and perceptions of people with advanced cancer and their family caregivers of shared decision-making, including how they and nurses are involved.

Design: Exploratory interview study.

Methods: Semistructured, individual interviews conducted in 2023 were analysed using reflexive thematic analysis.

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