United Kingdom Continence Society: Certification and Recertification in Urodynamics.

Aims: Patients coming for urodynamics expect those delivering the service to be fully trained, with assurance of competence and quality. This document proposes a single UKCS Certification and Re-certification process for all health care professionals who perform or interpret urodynamics.

Methods: The Working Group of the United Kingdom Continence Society engaged with stakeholders in relevant professional societies and institutions, recirculating drafts until consensus was reached.

Serum HER2 as potential prognostic biomarker in primary breast cancer patients.

Tissue expressed human epidermal growth factor receptor 2 (HER2) is an established parameter of breast cancer, and it is determined in routine clinical practice by histology. This study aims to assess the prognostic value of serum HER2 protein quantified using ELISA in 66 primary breast cancer patients. The median follow-up period was 94 months.

Do child and household regulation moderate the bidirectional relation between harsh parenting and externalizing problems in the transition to adolescence?

The present study examined several distinct indicators of regulation (i.e., task-based executive function, surveyed child effortful control, and surveyed household chaos) as moderators of longitudinal bidirectional links between developmental changes in harsh parenting (HP) and child externalizing behaviors (EXT) from age 9 to 14 years.

A cross-country comparison of temporal change in adolescent mental health problems in the UK and Brazil.

Aims: Epidemiological evidence shows a concerning rise in youth mental health difficulties over the past three decades. Most evidence, however, comes from countries in Europe or North America, with far less known about changes in other global regions. This study aimed to compare adolescent mental health across two population-based cohorts in the UK, and two population-based cohorts in Pelotas, Brazil.

Impact of Covid-19 on antenatal care: evidence from Madagascar Demographic and Health Survey.

Despite the growing literature on the impact of Covid-19 on antenatal care (ANC) and maternal/neonatal and child health outcomes globally, substantial knowledge gaps remain about the population-level impact in sub-Saharan Africa (SSA). Existing evidence on the ANC impact of Covid-19 in SSA is largely based on health facility or small-scale qualitative research, which are limited in providing population-level understanding. This paper examines the extent to which Covid-19 impacted ANC service utilisation and identifies what population sub-groups were most adversely impacted.

Using HINTS in acute vestibular syndrome: A practical guide for the acute care physician.

Acute vestibular syndrome (AVS) is a common clinical presentation. Common causes include peripheral, self-limiting labyrinthine disorders, but a significant proportion are caused by posterior circulation stroke (PoCS). Delineating between a peripheral versus central cause in AVS is challenging for acute care physicians, but a simple, three-step bedside test known collectively as the HINTS examination may be useful.

Bis(trimethylsilyl)phosphide chemistry: a half-century of advances across the periodic table.

Whilst bis(trimethylsilyl)amide has been used extensively as a ligand across the periodic table, the chemistry of its heavier group 15 congeners is relatively underdeveloped. However, bis(trimethylsilyl)phosphide coordination chemistry has provided unique structural motifs and has also shown potential applications in catalysis, materials science, and bioinorganic chemistry. This review, which marks 55 years since the first report of a bis(trimethylsilyl)phosphide complex, provides a comprehensive overview of the synthesis, characterisation and reactivity of structurally authenticated s-, p-, d- and f-block metal complexes of this ligand, focusing on salient single crystal XRD and NMR spectroscopic data.

The country house and the neoliberal society.

The English (or British) country house has enjoyed an under-appreciated social and economic revival in the last 25 years as a result of changes in the political economy associated with 'neoliberalism', which have benefitted both new buyers of country houses and old owners. One result of this revival has been the 're-privatization' of the country house, which has reduced its public profile. Recent interest in the cultural meanings of the country house-re-evaluated in light of empire, slavery, and nationalism-should take into account the greater insulation that neo-liberalism has lent these houses and their owners.

ERS Congress 2024: highlights from the Interstitial Lung Diseases Assembly.

https://bit.ly/3WAhw19.

ERS Congress 2024: highlights from the Allied Respiratory Professionals Assembly.

https://bit.ly/3ZPrlZw.

Natural killer cells in the lung: novel insight and future challenge in the airway diseases.

Natural killer (NK) cells are innate lymphoid cells which are present in the lung as circulating and resident cells. They are key players both in airway surveillance and in crosstalk with (COPD) pathogenesis, and they seem to contribute to the development of bronchiectasis. In asthma, NK cell dysfunction was observed mainly in severe forms, and it can lead to a biased type-2 immune response and failure in the resolution of eosinophilic inflammation that characterise both allergic and eosinophilic phenotypes.

Virucidal and Bactericidal Properties of Biocompatible Copper Textiles.

The COVID-19 pandemic highlights the global threat posed by emerging viruses, emphasizing the critical need for effective strategies to combat pathogen transmission. Moreover, alongside emerging viruses, the increasing threat of antimicrobial resistance further reinforces the need to develop novel methods for infection control. Anti-pathogenic coatings on textiles offer a promising solution; in this study, three electroless copper-plated fabrics are evaluated for their antipathogenic properties following International Standards Organisation (ISO) standards.

Mitigating Urban Heat Islands (UHI) Through Vegetation Restoration: Insights From Mining Communities.

Vegetation restoration plays a critical role in mitigating urban heat island (UHI) effects and improving local climate conditions, particularly in mining-affected areas. This study analyzes vegetation cover changes and their impact on UHI from 2000 to 2020 in three locations: Dexing City and Qibaoshan Township in China, and Dartford Ebbsfleet Garden City in the UK, using satellite imagery and remote sensing data. In Dexing City, the transition from open-pit to underground mining, combined with reclamation efforts, maintained a stable fractional vegetation cover (FVC) of 0.

Harnessing the power of genomics in hypertension: tip of the iceberg?

Despite the blaze of advancing knowledge on its complex genetic architecture, hypertension remains an elusive condition. Genetic studies of blood pressure have yielded bitter-sweet results thus far with the identification of more than 2,000 genetic loci, though the candidate causal genes and biological pathways remain largely unknown. The era of big data and sophisticated statistical tools has propelled insights into pathophysiology and causal inferences.

A study comparing positive benefits for parents, and their children, of children attending the UK's holiday activities and food program to parents of non-attendees.

The Holiday Activities and Food (HAF) is a UK Department for Education (DfE) funded program that provides free food and activities for 5-16-year-olds in receipt of means-tested free school meals. This evaluation focuses on parent/caregiver perceptions of HAF benefits during the 2021 and 2022 school holidays for a sample of parents/caregivers whose children attended HAF ( = 736) and a sample who did not attend HAF ( = 885). The results show that parents of children who attend HAF for 4 weeks (i.

Exercise as a welfare strategy? Insights from horse () owners in the UK.

Obesity and its comorbidities (e.g. laminitis) are identified as major welfare issues among domestic equids in the United Kingdom (UK) and abroad.

Protocol: Effectiveness of Sexual and Reproductive Health Blended Learning Approaches for Capacity Strengthening of Health Professionals in Low- and Middle-Income Countries: A Systematic Review.

This is the protocol for a Campbell systematic review. The objectives are as follows. The primary objective of this systematic review is to evaluate and synthesise both published and unpublished literature on the effectiveness of sexual and reproductive health blended learning approaches for capacity strengthening of healthcare practitioners in LMICs.

Mechanisms underpinning the effect of exercise on the non-alcoholic fatty liver disease: review.

Non-alcoholic Fatty Liver Disease (NAFLD) - whose terminology was recently replaced by metabolic liver disease (MAFLD) - is an accumulation of triglycerides in the liver of >5 % of its weight. Epidemiological studies indicated an association between NAFLD and reduced physical activity. In addition, exercise has been shown to improve NAFLD independently of weight loss.

The genome sequence of the Antarctic lanternfish, (Günther, 1878).

We present a genome assembly from an individual female (the Antarctic lanternfish; Chordata; Actinopterigii; Myctophiformes; Myctophidae). The genome sequence has a total length of 1,427.40 megabases.

Negotiating the ethical terrain in global value chains on the road towards the SDGs.

This paper employs a pattern matching approach to explore the tensions arising from differences in the ethical dispositions of multinational enterprise (MNE) buyers and their suppliers within the Bangladeshi apparel manufacturing sector. It examines how varying ethical principles shape the development, implementation, and outcomes of corporate social responsibility (CSR) and labor standards. Our analysis resulted in the identification of four scenarios: legitimacy with friction, mitigated forced alignment, collaborative enhancement, and principled resistance.

The environmental impact of intravenous antimicrobial therapies: a comparison of OPAT and inpatient administration care pathways.

Objectives: The urgent global threats of the climate crisis and antimicrobial resistance have the potential to be addressed in part by increasing the use of outpatient antimicrobial therapy (OPAT). Our study aimed to appraise the environmental impact of three commonly used OPAT pathways, and the traditional inpatient model of IV antimicrobial therapy.

Methods: We assessed the CO, waste and water footprint associated with self-care, nurse assisted and outpatient OPAT care pathways and inpatient administration of intravenous antibiotics to adult patients for whom OPAT was a viable treatment option.

Ischaemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer: a nationwide study.

Aims: Treatment of patients with cancer presenting with ST-elevation myocardial infarction (STEMI) is complex given the increased risk of both thrombotic and major bleeding complications.

Methods And Results: A nationally linked cohort of STEMI patients between January 2005 and March 2019 was obtained from the UK Myocardial Infarction National Audit Project and the UK National Hospital Episode Statistics Admitted Patient Care registries. The primary outcomes were major bleeding and re-infarction at 1 year following admission with STEMI.

Addressing the mental health needs of healthcare professionals in Africa: a scoping review of workplace interventions.

Healthcare workers in Africa face considerable stress due to factors like long working hours, heavy workloads and limited resources, leading to psychological distress. Generally, countries in the global north have well-established policies and employee wellness programs for mental health compared to countries in the global south. This scoping review aimed to synthesize evidence from published and grey literature on workplace mental health promotion interventions targeting African healthcare workers using Social Ecological Model (SEM) and the Job Demands-Resources (JD-R) model as an underlying theoretical framework for analysis.

Symptom networks of common mental disorders in public versus private healthcare settings in India.

We present a series of network analyses aiming to uncover the symptom constellations of depression, anxiety and somatization among 2,796 adult primary health care attendees in Goa, India, a low- and middle-income country (LMIC). Depression and anxiety are the leading neuropsychiatric causes of disability. Yet, the diagnostic boundaries and the characteristics of their dynamically intertwined symptom constellations remain obscure, particularly in non-Western settings.