Influence of pre-existing maternal diabetes mellitus on fetal myocardial performance index and systolic-to-diastolic duration ratio: a prospective cohort study.

Objective: To evaluate the influence of pre-existing maternal diabetes mellitus on fetal myocardial performance index and systolic-to-diastolic duration ratio.

Methods: Prospective cohort study included 179 pregnant women between 20 and 36w6d, divided into 3 groups: Group 1 (120, normal), Group 2 (31, type 1 diabetes mellitus), and Group 3 (28, type 2 diabetes mellitus). Systolic-to-diastolic duration ratio was calculated as the sum of isovolumic contraction time and ejection time divided by the sum of isovolumic relaxation time and ventricular filling time.

Acute effect of Dynamic Tape™ application to the gluteus medius muscle on lower limb kinetics in healthy women: A randomized controlled clinical trial.

Background: Dynamic tape™ (DT) is a biomechanical tape used to manage load directly, modify movement patterns, and assist functioning. Despite its increasing use in clinical practice, few studies have evaluated its effectiveness in improving postural stability, balance, and lower limb kinetics during jump landing tasks. This study aimed to investigate the acute effect of applying DT to the gluteus medius (GM) muscle on balance strategies during squatting, as well as on jump landing kinetics in asymptomatic active women.

Unlocking Probiotic Potential: Genomic Insights into Weissella paramesenteroides UFTM 2.6.1.

Weissella, a genus of lactic acid bacteria, has diverse beneficial attributes including probiotic activity and biotechnological applications. Therefore, the investigation of the Weissella genus has garnered growing interest. In this study, we sequenced the complete genome of Weissella paramesenteroides UFTM 2.

Balance evaluation in individuals with type 2 diabetes mellitus with and without peripheral neuropathy.

Background And Aims: Peripheral Diabetic Neuropathy (PDN) is the major complication of diabetes, and sensory-motor impairments can compromise balance, increasing the risk of falls and consequently can lead to functional disability. Thus, this study aims to evaluate the sensory and motor aspects of balance in individuals with type 2 diabetes mellitus with and without PDN.

Methods: This is a cross-sectional study which analyzed balance in 51 individuals, divided into three groups: G1 - individuals with Peripheral Diabetic Neuropathy; G2 - individuals with diabetics and without PDN; and G3 - individuals without Diabetes Mellitus.

Pilates increases resistance performance in young volleyball players.

Introduction: The aim of this work was to determine whether the Pilates method could promote changes in the activation and performance of core muscles in young volleyball players.

Method: Sixteen athletes (16.00 ± 1.

Prenatal Ultrasound Markers of Adverse Perinatal Outcomes in Newborns With Simple and Complex Gastroschisis.

Objective: The aim of this study was to compare prenatal ultrasound markers and perinatal outcomes in newborns with simple and complex gastroschisis.

Methods: A retrospective cohort study was performed on pregnant women with gastroschisis fetuses and their respective newborns between 2009 and 2019. Binary logistic regression was used to determine the best prenatal ultrasound markers of complex gastroschisis and adverse perinatal outcomes.

Targeting P-selectin and interleukin-1β in mice with sickle cell disease: effects on vaso-occlusion, liver injury and organ iron deposition.

Continuous vaso-occlusive and inflammatory processes cause extensive end-organ damage in adults with sickle cell disease (SCD), and there is little evidence that longterm hydroxyurea therapy prevents this. In initial trials, P-selectin blockade with crizanlizumab reduced SCD vaso-occlusive crisis frequency, and interleukin (IL)-1β inhibition in SCD patients, using canakinumab, lowered inflammatory markers. We used murine SCD models to examine the effects of acute and chronic blockade of Pselectin and of IL-1β on vaso-occlusive events, their inflammatory profile and organ health.

Reliability, Concurrent Validity, Responsiveness and Measurement Error of the Portuguese Version of Comprehensive Motor Coordination Scale in Individuals With Parkinson's Disease.

Introduction: Assessment of motor coordination in patients with Parkinson's disease (PD) is based on motor performance and does not consider movement quality.

Objective: To validate the Comprehensive Coordination Scale (CCS) in patients with PD and correlate it with motor impairment.

Methods: This cross-sectional and case-control study included 15 individuals with PD and 15 healthy older individuals as controls.

Fetal Cardiac Intervention: A Comprehensive Review of Current Evidence.

Fetal cardiac intervention consists of a novel and evolving technique for the intrauterine treatment of a subset of patients with congenital heart diseases, which aims to improve hemodynamics, reduce secondary damage, and achieve better postnatal outcomes. Nevertheless, the risks and benefits of this therapy remains subject to controversy. This review describes the rationale, selection criteria, and technical features for the most frequently performed fetal cardiac interventions.

Analysis of the association between different domains and intensities of physical activity in adults: An observational and cross-sectional study.

Background And Objective: To analyze the association between different domains and intensities of physical activity (PA) in adults.

Methods: 269 participants were randomly selected in a community-dwelling representative sampling process. The habitual PA practice was assessed in different domains (occupational, sports practice, and leisure time/commuting) using Baecke's questionnaire and in different intensities (light, moderate, vigorous, and very vigorous) by accelerometry.

Individual, family, school and neighborhood predictors related to different levels of physical activity in adolescents: A cross-sectional study.

The aim of this study was to investigate the association among individual, family, school environment and neighborhood predictors with the different levels of physical activity (PA) [light (LPA) and moderate to vigorous PA (MVPA)] in Brazilian adolescents. A cross-sectional study was carried out with 309 adolescents with a mean age of 15.37 (± 0.

Unveiling the role of exercise in modulating plasma heat shock protein 27 levels: insights for exercise immunology and cardiovascular health.

Cardiovascular disease is one of the leading causes of mortality worldwide, primarily driven by atherosclerosis, a chronic inflammatory condition contributing significantly to fatalities. Various biological determinants affecting cardiovascular health across different age and sex groups have been identified. In this context, recent attention has focused on the potential therapeutic and preventive role of increasing circulating levels of heat shock protein 27 (plasma HSP27) in combating atherosclerosis.

Influence of Cesarean Section Scar on the Mean Pulsatility Index of the Uterine Artery Doppler between 20 and 34 Weeks of Gestation.

Objective: The aim of this study was to assess the influence of the cesarean section scars on the mean pulsatility index (PI) of the uterine artery Doppler between 20 and 34 weeks of gestation. A secondary objective was to assess the association between previous cesarean section and adverse maternal/perinatal outcomes.

Methods: A retrospective cohort study was conducted with pregnant women who had their deliveries between March 2014 and February 2023.

Postmenopausal women treated for breast cancer with insulin resistance: clinical, analytical, cross-sectional.

This study aims to investigate the potential association between serum levels of cytokines, HSP60, HSP70 and IR (HOMA-IR) in postmenopausal women. We conducted a cross-sectional study involving 381 postmenopausal women, including 94 with a breast cancer diagnosis and 278 without. We analyzed anthropometric and laboratory measurements.

Decompressive Craniectomy in Patients with Malignant Stroke with Additional Vascular Territory.

Background: Decompressive craniectomy substantially reduces mortality and disability rates following a malignant stroke. This procedure remains a life-saving option, especially in contexts with little access to mechanical thrombectomy despite downward trends in the performance of decompressive craniectomy due to discussions on the acceptance of living with severe disabilities. However, the outcomes of the surgery in cases involving concomitant occlusion of anterior or posterior cerebral arteries have not been extensively studied.

Identification of SNP Markers and Candidate Genes Associated with Major Agronomic Traits in .

Genome-wide association studies (GWASs) allow for inferences about the relationships between genomic variants and phenotypic traits in natural or breeding populations. However, few have used this methodology in . We aimed to identify chromosomal regions with significant associations between SNP markers and agronomic traits in .

Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold.

Background And Aim: Although it is well established that hormones like glucagon stimulates gluconeogenesis via the PKA-mediated phosphorylation of CREB and dephosphorylation of the cAMP-regulated CREB coactivators CRTC2, the role of neural signals in the regulation of gluconeogenesis remains uncertain.

Methods And Results: Here, we characterize the noradrenergic bundle architecture in mouse liver; we show that the sympathoexcitation induced by acute cold exposure promotes hyperglycemia and upregulation of gluconeogenesis via triggering of the CREB/CRTC2 pathway. Following its induction by dephosphorylation, CRTC2 translocates to the nucleus and drives the transcription of key gluconeogenic genes.

Relationships among lateral medicine ball throw test performance, HIP and trunk muscle strength, and lower limb kinematics: A cross-sectional study.

Introduction: The lateral medicine ball throw (LMBT) test is used to evaluate the throwing action, involving the entire kinetic chain and the principle of force transfer, with association between the strength of the lower limb and trunk muscles and the lower limb kinematics. The LMBT to investigate the association between lower limb kinematics and hip and trunk muscle strength.

Experimental: This was a cross-sectional study with 84 healthy and physically active young people.

Acute effects of a pilates method session on flexibility and performance in practitioners of an extreme conditioning program: A preliminary study.

Introduction: The aim of this study was to evaluate the acute effects of Pilates exercises on flexibility and performance in practitioners of an extreme conditioning program (ECP). The hypothesis adopted was that Pilates could activate deeper muscles and improve the stability of core muscles.

Methods: This was an observational cross-sectional study with individuals practicing an ECP submitted to a Pilates method (PM) exercise session.

How to train your dragon: absolute conditioning in larval dragonflies.

Insects, despite possessing relatively small brains, exhibit noteworthy adaptive behaviors, making them intriguing subjects for understanding learning mechanisms. This study explores the learning capabilities of dragonfly larvae (Anisoptera: Aeshnidae) in conditioning experiments, shedding light on the cognitive processes that underpin their remarkable abilities. As apex predators, dragonflies play a crucial role in ecosystems, necessitating a diverse range of learning behaviors for survival and reproductive success.

Intramuscular adipose tissue, muscle area, and power as predictors of performance in breast cancer survivors.

Purpose: The decline in physical performance, assessed by physical tests such as the timed up and go (TUG) test, is a consequence of reduced physiological reserves at higher levels of a hierarchical process. This occurs due to changes in muscle architecture, including atrophy and fat infiltration into the muscles, which in turn lead to changes in muscle function, resulting in reduced muscle strength and power and, consequently, affecting physical performance. This study investigated predictive factors for physical performance in breast cancer survivor (BCS), focusing on intramuscular adipose tissue (IMAT), quadríceps muscle area (QMA), and muscular power.