A systematic review of AI-based chatbot usages in healthcare services.

Purpose: This systematic literature review aims to provide a comprehensive and structured synthesis of the existing knowledge about chatbots in healthcare from both a theoretical and methodological perspective.

Design/methodology/approach: To this end, a systematic literature review was conducted with 89 articles selected through a SPAR-4-SLR systematic procedure. The document for this systematic review was collected from Scopus database.

COMPARISON OF VARIOUS PSYCHOLOGICAL HUMAN NEED MODELS WITH SCHEMA THERAPY.

Several theories have been proposed over the last few decades on identifying various fundamental psychological human needs. These theories were compared to a more recent theory using concepts from a fast growing form of psychotherapy called schema therapy. The empirical basis of the model from schema therapy was provided using Eastern and Western samples.

Whole genome analysis revealed the role of and genes in carbapenem resistance of strains.

is a multidrug-resistant bacterium that has emerged as a significant nosocomial pathogen globally and renowned for its ability to acquire antimicrobial resistance (AMR) genes. However, understanding of its resistance mechanisms to certain drug classes remains limited. This study focused on four bacterial strains (AB863, AB889, AB930, and AB960) exhibiting carbapenem resistance.

Untargeted metabolomics profiling for revealing water-soluble bioactive components and biological activities in edible bird's nest.

Edible bird's nest (EBN) is a functional food renowned for its numerous health benefits. While its nutritional and therapeutic value is well-documented, the metabolites contributing to the bioactivities of EBN remain poorly understood. This study aimed to identify the metabolites present in EBN subjected to different treatments, including double-boiled EBN (EBN), EBN hydrolysate (EBN), EBN fermented with Lactobacillus helveticus (EBN), Latilactobacillus curvatus (EBN), and Latilactobacillus sakei (EBN) using liquid chromatography-mass spectrometry (LC-MS) and correlate the identified bioactive metabolites with the bioactivities of EBN.

A starch/gelatin-based Halochromic film with black currant anthocyanin and Nanocellulose-stabilized cinnamon essential oil Pickering emulsion: Towards real-time Salmon freshness assessment.

Neoterically, food packaging systems designed solely for prolonging shelf life or monitoring freshness could not fulfil the dynamic demands of consumers. In this current investigation, using the solvent casting method, a versatile halochromic indicator was created by integrating black currant anthocyanin and cinnamon essential oil-loaded Pickering emulsion into a starch/gelatin matrix. The resulting indicator film underwent scrutiny for its structural, pH-sensitive, antioxidant, and antimicrobial attributes.

One-pot extraction of nanocellulose from raw durian husk fiber using carboxylic acid-based deep eutectic solvent with in situ ultrasound assistance.

Nanocellulose (CNF) has emerged as a promising alternative to synthetic petroleum-based polymers, but the conventional preparation process involves multiple tedious steps, heavily dependent on chemical input, and proves cost-inefficient. This study presented an, in situ ultrasound-assisted extraction using deep eutectic solvent (DES) based on choline chloride and oxalic acid for more facile production of CNF from raw durian husk fibers. FESEM analysis confirmed the successful extraction of web-like nanofibril structure with width size ranging from 18 to 26 nm.

Fractionation and characterisation of sialylated-mucin glycoprotein from edible birds' nest hydrolysates through anion exchange chromatography.

Edible bird's nest (EBN) is made up of sialylated-mucin glycoprotein with various health benefits due to its high antioxidative activity. However, as a macromolecule with distinct charged sialic acid and amino acids, fractions with different charges would have varied physicochemical properties and antioxidant activity, which have not been studied. Therefore, this study aimed to fractionate and purify the enzymatic hydrolysed of cleaned EBN (EBNh) and EBN by-product (EBNh) through anion exchange chromatography (AEC), and determine their molecular weights, physicochemical properties, and antioxidative activities.

Poroelastic modelling of brain tissue swelling and decompressive craniectomy treatment in ischaemic stroke.

Brain oedema or tissue swelling that develops after ischaemic stroke can cause detrimental effects, including brain herniation and increased intracranial pressure (ICP). These effects can be reduced by performing a decompressive craniectomy (DC) operation, in which a portion of the skull is removed to allow swollen brain tissue to expand outside the skull. In this study, a poroelastic model is used to investigate the effect of brain ischaemic infarct size and location on the severity of brain tissue swelling.

Preparation and evaluation of a niosomal delivery system containing extract and study of its anti- activity.

extract (GME) has severe pharmacokinetic deficiencies and is made up of a variety of bioactive components. GME has proven its anti- effectiveness. In this investigation, a GME-loaded niosome was developed to increase its potential therapeutic efficacy.

Glucosamine substituted sulfonylureas: IRS-PI3K-PKC-AKT-GLUT4 insulin signalling pathway intriguing agent.

Normally, skeletal muscle accounts for 70-80% of insulin-stimulated glucose uptake in the postprandial hyperglycemia state. Consequently, abnormalities in glucose uptake by skeletal muscle or insulin resistance (IR) are deemed as initial metabolic defects in the pathogenesis of type 2 diabetes mellitus (T2DM). Globally, T2DM is growing in exponential proportion.

Dataset of biological community structure in Deepor Beel using eDNA approach-A RAMSAR wetland of Assam, India.

Deepor Beel, located in the state of Assam in India, is a Wetland of International Importance with a Wildlife Sanctuary and is the only RAMSAR site in the state. Though of invaluable ecological significance, the wetland is facing anthropogenic stressors, leading to rapid degradation of ecological health. In December 2022, surface water was collected from six stations of Deepor Beel to elucidate biological communities using the eDNA approach.

The impact of an online educational game on breast cancer awareness among university female students, Malaysia: a pilot study.

Background: Breast cancer is one of the world's most prevalent cancer and the most common type of cancer in Malaysia. Interestingly, breast cancer in young women is more aggressive compared to older women and the survival rate among these groups of individuals is poor. Thus, breast cancer awareness is essential among young women as early detection is possible and treatment will be effective during which the disease is curable.

Facile Preparation of Durable and Eco-Friendly Superhydrophobic Filter with Self-Healing Ability for Efficient Oil/Water Separation.

The superhydrophobic feature is highly desirable for oil/water separation (OWS) operation to achieve excellent separation efficiency. However, using hazardous materials in fabricating superhydrophobic surfaces is always the main concern. Herein, superhydrophobic filters were prepared via an eco-friendly approach by anchoring silica particles (SiO) onto the cotton fabric surface, followed by surface coating using natural material-myristic acid via a dip coating method.

Effect of Secretion Efficiency of Mutant KRAS Neoantigen by on the Immune Response of a Mucosal Vaccine Delivery Vehicle Targeting Colorectal Cancer.

Colorectal cancer (CRC) is often caused by mutations in the KRAS oncogene, making KRAS neoantigens a promising vaccine candidate for immunotherapy. Secreting KRAS antigens using live Generally Recognized as Safe (GRAS) vaccine delivery hosts such as is deemed to be an effective strategy in inducing specific desired responses. Recently, through the engineering of a novel signal peptide SPK1 from an optimized secretion system was developed in the NZ9000 host.

Asthma control and care among six public health clinic attenders in Malaysia: A cross-sectional study.

Background And Aims: Asthma is common in Malaysia but neglected. Achieving optimal asthma control and care is a challenge in the primary care setting. In this study, we aimed to identify the risk factors for poor asthma control and pattern of care among adults and children (5-17 years old) with asthma attending six public health clinics in Klang District, Malaysia.

Determinants of CSR and green purchase intention: Mediating role of customer green psychology during COVID-19 pandemic.

COVID-19 is a viral disease also comprehended as a coronavirus pandemic that has compelled the world to revisit business strategies to encounter COVID-19 challenges. Over the last decade, ample research has been accomplished on corporate social responsibility (CSR) and circular economy. Nevertheless, a key research gap requires to be filled that how CSR can perform a foremost role in engaging stakeholders like consumers during the COVID-19 era.

Clinical Investigation of Chemotherapeutic Resistance and miRNA Expressions in Head and Neck Cancers: A Thorough PRISMA Compliant Systematic Review and Comprehensive Meta-Analysis.

: Chemoresistance is a significant barrier to combating head and neck cancer, and decoding this resistance can widen the therapeutic application of such chemotherapeutic drugs. This systematic review and meta-analysis explores the influence of microRNA (miRNA) expressions on chemoresistance in head and neck cancers (HNC). The objective is to evaluate the theragnostic effects of microRNA expressions on chemoresistance in HNC patients and investigate the utility of miRNAs as biomarkers and avenues for new therapeutic targets.

The spatial distribution of physicochemical parameters in coastal sediments along the Bay of Bengal Coastal Zone with statistical analysis.

The current study focused on the monitoring of pollution loads in the Kalpakkam coastal zone of India in terms of physico-chemical characteristics of sediment. The investigation took place at 12 sampling points around the Kalpakkam coastal zone for one year beginning from 2019. The seasonal change of nutrients in the sediment, such as nitrogen, phosphorus, potassium, total organic carbon, and particles size distribution, was calculated.

Optimization of Signal Peptide via Site-Directed Mutagenesis for Enhanced Secretion of Heterologous Proteins in .

Secretion efficiency of heterologous proteins in the Generally Regarded As Safe (GRAS) is often reported to be insufficiently low due to limitations such as poor targeting and translocation by the signal peptide or degradation by the host proteases. In this study, the secretion efficiency in the host was enhanced through the utilization of a heterologous signal peptide (SP) SPK1 of . The SPK1 was subjected to site-directed mutations targeting its tripartite N-, H-, and C-domains, and the effect on secretion efficiency as compared to the wild-type SPK1 and native lactococcal USP45 was determined on a reporter nuclease (NUC) of .

COVID-19 vaccine hesitancy and its associated factors in Malaysia.

The success of the COVID-19 vaccination programme to achieve herd immunity depends on the proportion of the population inoculated. COVID-19 vaccination hesitancy is a barrier to reaching a sufficient number of people to achieve herd immunity. This study aims to determine the prevalence of COVID-19 vaccine hesitancy and to identify the reasons contributing to vaccine hesitancy using the Theory of Planned Behavior.

The association between diabetes and obesity with Dengue infections.

Dengue, an arboviral disease is a global threat to public health as the number of Dengue cases increases through the decades and this trend is predicted to continue. Non-communicable diseases such as diabetes and obesity are also on an upward trend. Moreover, past clinical studies have shown comorbidities worsen the clinical manifestation of especially Severe Dengue.

The Role of Family Life and the Influence of Peer Pressure on Delinquency: Qualitative Evidence from Malaysia.

Juvenile delinquency is always seen as a public health problem which needs intervention at various levels. Identifying which factors may lead juveniles to delinquency is a long-standing question among criminologists. This remains the case in Malaysia.

Evaluation of Smoking Prevalence, Secondhand Smoke Exposure, Attitudes of Tobacco Control, and Smoking Cessation Knowledge among Pharmacy and Medical Students in a Private University, Malaysia.

Background: Tobacco use is one of the leading causes of premature morbidity and mortality globally, causing over eight million deaths per year. One of the best approaches to reduce smoking-related deaths is to encourage future health-care professionals in tobacco control programs.

Objectives: To assess the smoking prevalence, secondhand smoke exposure, attitudes toward tobacco control, and smoking cessation knowledge and associated factors among pharmacy and medical students in a private university in Malaysia.

Experimental study on total coliform violations in the complied NHCL, O and UV treated municipal water supply system.

Water quality has become a severe concern on a global scale, owing mostly to the rapid increase of the nation's development. According to Malaysia's Natural Resources and Environment Ministry, poor water management is the primary cause of the country's water quality problems. Many river systems are polluted by home and industrial pollutants, according to the findings of research in Malaysia and comparable difficulties in a few other nations.