Pathophysiology of Medication-Related Osteonecrosis of the Jaw-A Minireview.

Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse effect of antiresorptive medications administered for control of osseous malignancy, osteoporosis, or other bone metabolic diseases. Despite being reported in the literature two decades ago, MRONJ etiology, pathophysiology, and progression remain largely unknown, and current nonoperative or operative treatment strategies are mostly empirical. Several hypotheses that attempt to explain the mechanisms of MRONJ pathogenesis have been proposed.

Development and validation of a mA RNA methylation regulators-based signature for predicting the prognosis of head and neck squamous cell carcinoma.

Head and neck squamous cell carcinoma (HNSCC) is among the most common types of cancers that threat the public health worldwide. A growing body of evidence has demonstrated that mA RNA methylation plays a critical role in tumorigenesis. However, the association between mA RNA methylation regulators and prognosis of HNSCC remains poorly known.

Lingual frenuloplasty with myofunctional therapy: Exploring safety and efficacy in 348 cases.

Background: Ankyloglossia is a condition of altered tongue mobility due to the presence of restrictive tissue between the undersurface of the tongue and the floor of mouth. Potential implications of restricted tongue mobility (such as mouth breathing, snoring, dental clenching, and myofascial tension) remain underappreciated due to limited peer-reviewed evidence. Here, we explore the safety and efficacy of lingual frenuloplasty and myofunctional therapy for the treatment of these conditions in a large and diverse cohort of patients with restricted tongue mobility.

Water vapor absorption allows for volume expansion during molting in and (Crustacea, Isopoda, Oniscidea).

Arthropods require periodic molting in order to grow which presents a number of challenges to terrestrial taxa. Following ecdysis, the pliant new cuticle is susceptible to buckling under gravity and requires elevated hydrostatic pressure for support. Terrestrial species also require a mechanism of volume expansion and stretching of the integument prior to sclerotization, a need that is readily met in aquatic arthropods by drinking.

A three miRNAs signature for predicting the transformation of oral leukoplakia to oral squamous cell carcinoma.

Oral squamous cell carcinoma (OSCC) remains to be a global health problem. However, the underlying molecular mechanisms regulating the oral leukoplakia (OLK) to OSCC remain poorly known. MicroRNAs (miRNAs) expression profiles of GSE33299 and GSE62809 were downloaded from gene expression omnibus (GEO) respectively.

Biocompatibility of 4-META/MMA-TBB resin used as a dental luting agent.

Statement Of Problem: The bonding and biological properties of currently used luting/cementing materials need to be improved. 4-Acryloyloxyethyl trimellitate anhydride/methyl methacrylate-tri-n-butylborane (4-META/MMA-TBB) resin is primarily used for splinting mobile teeth or treating fractured teeth. It undergoes moisture-resistant polymerization and bonds strongly to dentin and metals.

Predictors of treatment preference for mandibular fracture.

Background: Patient treatment preferences do not necessarily remain stable over time.

Objective: This study focuses on predictors of patient treatment choice and on the extent to which patients are willing to take risks by choosing surgical versus nonsurgical treatment for mandibular fracture.

Methods: Surveys of African-American and Hispanic adults receiving treatment at King/Drew Medical Center for either a mandibular fracture (n = 98) or third-molar removal (n = 105) were used to investigate patterns of patient preference over the course of a 4-month study period using generalized estimating equations controlling for age, gender, income, and fracture versus third-molar patient.