Clinical Manifestations.

Background: Similar neuroimaging abnormalities are reported in post-COVID patients and patients with AD. Moreover, COVID-19 and Alzheimer's Disease (AD) share genetic vulnerabilities and have similar cognitive symptoms of COVID (e.g.

Clinical Manifestations.

Background: Semantic memory assessments are sensitive indicators of cognitive decline in pre-clinical Alzheimer's Disease (AD), with slowed reaction time and diminished accuracy serving as markers for amyloid accumulation. We introduce the Semantic Stroop Test-a brief (4.3 minute), automated semantic retrieval and executive function task included in the California Cognitive Assessment Battery (CCAB).

Clinical Manifestations.

Background: Cognitive-test scores in the bottom 7% of a normative distribution (z-score < -1.50) are an essential component of the diagnosis of Mild Cognitive Impairment (MCI). However, different patients show MCI-compatible performance when evaluated using scoring models that account for the influences of different demographic variables (e.

Clinical Manifestations.

Background: The administration of cognitive tests in patients' homes facilitates access by underserved communities and increases testing capacity and efficiency. However, the validity of at-home computerized cognitive tests is often questioned because of limitations in examiner monitoring, distractions, environmental noise, and potential cheating. Here, we compare performance of the computerized and proctored California Cognitive Assessment Battery (CCAB) when administered at-home or in the laboratory using otherwise identical procedures.

The Psychometric Properties of the Universal Design in Healthcare Education Instrument.

Background And Purpose: Universal design (UD) teaching approaches provide access to learning environments for diverse postsecondary students; however, UD practices in healthcare education have rarely been examined. The purpose of this study was to evaluate the construct validity and reliability of the revised Universal Design in Healthcare Education (UDinHE) instrument.

Methods: The exploratory structural equation model (ESEM).

Prevention of white-matter lesions through control of cerebrovascular risk factors.

Multiple epidemiological and brain imaging studies show a strong association between elevations in systolic blood pressure and lesions of cerebral white matter. The association between white-matter lesions and systolic blood pressure persists even if individuals are receiving treatment, suggesting that these individuals may be undertreated. In addition, these studies suggest that lesions of cerebral white matter may serve as markers for atherosclerotic vascular disease.

Application of item response theory for development of a global functioning measure of dementia with linear measurement properties.

An ideal measure of global functioning for patients with dementia would discriminate at very high and very low levels of functioning and would have linear measurement properties such that a given change in score corresponds to the same amount of change in underlying ability at any part of the ability continuum. Using item response theory methods, linearity of test measurement can be directly assessed and items can be selected to construct a test with desired measurement characteristics. The purpose of this study was to apply item response theory methods to evaluating and developing global functioning scales.