Hydrophilic magnetic COFs: The Answer to photocatalytic degradation and removal of imidacloprid insecticide.

The widespread use of imidacloprid (IMI) in pest control presents significant environmental challenges due to its persistence and low removal efficiency. This study introduces magnetic Covalent Organic Frameworks (COFs) functionalized with Fe₃O₄ nanoparticles (Fe₃O₄@HMN-COF, Fe₃O₄@MAN-COF, and Fe₃O₄@SIN-COF) as efficient adsorbents for IMI removal from water. These COFs, engineered with nitrogen-rich structures and extensive π-electron systems, achieve superior adsorption through π-π interactions, hydrophobic interactions, and hydrogen bonding.

Effects of interaction of multiple large-scale atmospheric circulations on precipitation dynamics in China.

Different scenarios of precipitation, that lead to such phenomena as droughts and floods are influenced by concurrent multiple teleconnection factors. However, the multivariate relationship between precipitation indices and teleconnection factors, including large-scale atmospheric circulations and sea surface temperature signals in China, is rarely explored. Understanding this relationship is crucial for drought early warning systems and effective response strategies.

Synthesizing covalent organic frameworks for unprecedented iodine capture performance.

Nuclear energy continues to be an important supplier of electricity, but it has problems with waste management and the possibility to leak radioactive material. Iodine, a potentially harmful byproduct of uranium fission, is hazardous to both the environment and human health. Therefore, developing safe, effective, and affordable storage facilities for iodine waste is crucial.

Effectiveness of Ultrasound-guided versus Landmark-based Glucocorticoid Injection in the Treatment of First Carpometacarpal Joint Osteoarthritis.

Osteoarthritis is a debilitating degenerative disease more pronounced in elderly affecting many joints. The first carpometacarpal joint (CMC1) is commonly affected. Pain is the major complaint, which can impact patient's daily activities.

Nano-evolution and protein-based enzymatic evolution predicts novel types of natural product nanozymes of traditional Chinese medicine: cases of herbzymes of Taishan-Huangjing () and Goji ().

Nanozymes and natural product-derived herbzymes have been identified in different types of enzymes simulating the natural protein-based enzyme function. How to explore and predict enzyme types of novel nanozymes when synthesized remains elusive. An informed analysis might be useful for the prediction.

Assimilation of Both Column- and Layer-Integrated Dust Opacity Observations in the Martian Atmosphere.

A new dust data assimilation scheme has been developed for the UK version of the Laboratoire de Météorologie Dynamique Martian General Circulation Model. The Analysis Correction scheme (adapted from the UK Met Office) is applied with active dust lifting and transport to analyze measurements of temperature, and both column-integrated dust optical depth (CIDO), (rescaled to a reference level), and layer-integrated dust opacity (LIDO). The results are shown to converge to the assimilated observations, but assimilating either of the dust observation types separately does not produce the best analysis.

A 16S rRNA Sequencing Study Describing the Environmental Microbiota of Two Powdered Infant Formula Built Facilities.

Microbial safety is critically important for powdered infant formula (PIF) fed to neonates, with under-developed immune systems. The quality and safety of food products are dictated by those microorganisms found in both raw materials and the built production environment. In this study, a 2-year monitoring program of a production environment was carried out in two PIF factories located in the Republic of Ireland, and the environmental microbiome in different care areas of these sites was studied by using a 16S ribosomal RNA (rRNA)-based sequencing technique.

Detection of SARS-CoV-2 in COVID-19 Patient Nasal Swab Samples Using Signal Processing.

This work presents an opto-electrical method that measures the viral nucleocapsid protein and anti-N antibody interactions to differentiate between SARS-CoV-2 negative and positive nasal swab samples. Upon light exposure of the patient nasal swab sample mixed with the anti-N antibody, charge transfer (CT) transitions within the altered protein folds are initiated between the charged amino acids side chain moieties and the peptide backbone that play the role of donor and acceptor groups. A Figure of Merit (FOM) was introduced to correlate the relative variations of the samples with and without antibody at two different voltages.

The Discovery of Potent SHP2 Inhibitors with Anti-Proliferative Activity in Breast Cancer Cell Lines.

Despite available treatments, breast cancer is the leading cause of cancer-related death. Knowing that the tyrosine phosphatase SHP2 is a regulator in tumorigenesis, developing inhibitors of SHP2 in breast cells is crucial. Our study investigated the effects of new compounds, purchased from NSC, on the phosphatase activity of SHP2 and the modulation of breast cancer cell lines' proliferation and viability.

Reticular design and crystal structure determination of covalent organic frameworks.

Reticular chemistry of covalent organic frameworks (COFs) deals with the linking of discrete organic molecular building units into extended structures adopting various topologies by strong covalent bonds. The past decade has witnessed a rapid development of COF chemistry in terms of both structural diversity and applications. From the structural perspective, irrespective of our subject of concern with regard to COFs, it is inevitable to take into account the structural aspects of COFs in all dimensions from 1D ribbons to 3D frameworks, for which understanding the concepts of reticular chemistry, based mainly on 'reticular design', will seemingly lead to unlimited ways of exploring the exquisiteness of this advanced class of porous, extended, and crystalline materials.

Age-Related Sex Differences in Clinical Presentation, Management, and Outcomes in ST-Segment-Elevation Myocardial Infarction: Pooled Analysis of 15 532 Patients From 7 Arabian Gulf Registries.

Background No studies from the Arabian Gulf region have taken age into account when examining sex differences in ST-segment-elevation myocardial infarction (STEMI) presentation and outcomes. We examined the relationship between sex differences and presenting characteristics, revascularization procedures, and in-hospital mortality after accounting for age in patients hospitalized with STEMI in the Arabian Gulf region from 2005 to 2017. Methods and Results This study was a pooled analysis of 31 620 patients with a diagnosis of acute coronary syndrome enrolled in 7 Arabian Gulf registries.

Prevalence of diabetes and cardio-metabolic risk factors in young men in the United Arab Emirates: A cross-sectional national survey.

Introduction: The aim of the study was to determine the prevalence of cardio-metabolic risk factors in men under 30 in the United Arab Emirates.

Methods: This cross-sectional observational study included 33 327 Emirati men aged 18-29 attending an obligatory standardized medical examination between May 2015 and February 2017. Body mass index, fasting blood glucose, total cholesterol, triglycerides and blood pressure were assessed.

Antibacterial activity and mechanism of action of the benzazole acrylonitrile-based compounds: In vitro, spectroscopic, and docking studies.

A new series of pyrimidine derivatives 5, 9a-d and 12a-d was synthesized by an efficient procedure. The antibacterial activity of the new compounds was studied against four bacterial strains. Compound 5 was found to exhibit the highest potency, with = 1.

Enzymatic pre-treatment of microalgae cells for enhanced extraction of proteins.

Crude proteins and pigments were extracted from different microalgae strains, both marine and freshwater. The effectiveness of enzymatic pre-treatment prior to protein extraction was evaluated and compared to conventional techniques, including ultrasonication and high-pressure water extraction. Enzymatic pre-treatment was chosen as it could be carried out at mild shear conditions and does not subject the proteins to high temperatures, as with the ultrasonication approach.

The PI3Kδ inhibitor idelalisib suppresses liver and lung cellular respiration.

Idelalisib (an inhibitor of phosphatidylinositol-3-kinase-delta) is approved for treatment of B-cell malignancies, with a Boxed Warning concerning potentially fatal hepatic, lung, and intestinal toxicities. The mechanisms of these tissue-specific adverse events have yet to be elucidated. This in vitro study investigated whether these effects could be attributed, at least in part, to altered cellular bioenergetics.

Lead exposure causes thyroid abnormalities in diabetic rats.

Lead is a widely-spread environmental pollutant and a commonly-used industrial chemical that can cause multisystemic adverse health effects. However, the effects of lead exposure on diabetic animals have not been reported so far. The aim of this study is to evaluate the effects of lead exposure on thyroid, renal and oxidative stress markers in diabetic Wistar rats.

The mTOR inhibitor sirolimus suppresses renal, hepatic, and cardiac tissue cellular respiration.

The purpose of this in vitro study was to develop a useful biomarker (e.g., cellular respiration, or mitochondrial O2 consumption) for measuring activities of mTOR inhibitors.

The mTOR inhibitor sirolimus suppresses renal, hepatic, and cardiac tissue cellular respiration.

The purpose of this in vitro study was to develop a useful biomarker (e.g., cellular respiration, or mitochondrial O2 consumption) for measuring activities of mTOR inhibitors.

Spatial patterns and links between microbial community composition and function in cyanobacterial mats.

We imaged reflectance and variable fluorescence in 25 cyanobacterial mats from four distant sites around the globe to assess, at different scales of resolution, spatial variabilities in the physiological parameters characterizing their photosynthetic capacity, including the absorptivity by chlorophyll a (A chl), maximum quantum yield of photosynthesis (Y max), and light acclimation irradiance (I k). Generally, these parameters significantly varied within individual mats on a sub-millimeter scale, with about 2-fold higher variability in the vertical than in the horizontal direction. The average vertical profiles of Ymax and I k decreased with depth in the mat, while A chl exhibited a sub-surface maximum.

Obesity hypoventilation syndrome in obstructive sleep apnea patients in the United Arab Emirates: a retrospective cross-sectional study.

Objectives: To estimate the frequency of symptoms of obesity hypoventilation syndrome (OHS) in patients with obstructive sleep apnoea (OSA) and to evaluate comorbidities associated with OHS.

Design: Retrospective study based on patients' medical records and on further sleep tests performed in the study centre during the inclusion visit.

Setting: Respiratory Care Unit and Sleep Disorder Centre of the Zayed Military Hospital United Arab Emirates.

Use of light traps and differing light color to investigate seasonal abundance of the date palm pest, Oryctes agamemnon arabicus (Coleoptera: Scarabaeidae).

Oryctes agamemnon arabicus (Fairmaire) (Coleoptera: Scarabaeidae) is a date palm insect pest that causes damage to trunk and roots and can damage grass lawns in the United Arab Emirates (UAE) and other countries such as Oman, Saudi Arabia, and Tunisia. The goal of this study was to monitor population dynamics and to evaluate six light colors (white, green, red, yellow, blue, and infrared) and two lamp types (mercury and energy-saving) in light traps. Experiments were performed on a date palm farm during a 2 yr period (2010 and 2011).

Frequency of peptic ulcer disease during and after Ramadan in a United Arab Emirates hospital.

We aimed to study the effect of Ramadan fasting on the occurrence of peptic ulcer disease and its complications in patients presenting to the Accident and Emergency Department at Al-Ain hospital, United Arab Emirates (UAE). We retrospectively reviewed patient records over the 10-year period, 1992 to 2002. Of 470 patients treated for peptic ulcer disease, 215 were seen during Ramadan and 255 in the month after Ramadan.

Al-Ain community psychiatric survey IV: socio-cultural changes (traditionality-liberalism) and prevalence of psychiatric disorders.

Unlabelled: BACKGROUND This study was set to explore the relationship between socio-cultural change and psychopathology.

Method: A representative sample (n = 1,394) of Al-Ain adult population had their psychopathology assessed with the Composite International Diagnostic Interview and other self-reported questionnaires, while the socio-cultural change was assessed with the modified version of the Socio-cultural Change Questionnaire (ScCQ). The reliability and construct validity of the modified ScCQ were assessed.

An audit of general practitioner referrals for pelvic ultrasound.

Pelvic ultrasound is a widely used diagnostic tool and access to this investigation is not universally available to all general practitioners (GPs). The aim of this study was to assess if GPs working in the United Arab Emirates (UAE) were using pelvic ultrasound appropriately by determining the rates of diagnostic yield and referral after the investigation. It was then ascertained if these results were affected by the post-graduate training or gender of the doctor.

Beta-haemolytic streptococci among primary school children in Al-Ain (UAE).

A survey of 601 school children aged 5.5 to 9.5 years found that 9.