1,511 results match your criteria: "U1219; and University of Bordeaux F.C.[Affiliation]"
Front Pharmacol
November 2024
Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Disproportionality analyses are the most-commonly used study design used in the post-marketing phase to detect suspected adverse drug reactions in individual case safety reports. Recent years have witnessed an exponential increase in published articles on disproportionality analyses, thanks to publicly accessible databases. Unfortunately, this trend was accompanied by concerns on lack of transparency and misinterpretation of results, both generating unjustified alarm and diluting true signals into overwhelming noise.
View Article and Find Full Text PDFLiver Int
January 2025
Disease Elimination Program, Burnet Institute, Melbourne, Australia.
Subst Use Misuse
January 2025
Centre d'étude des mouvements sociaux (Inserm U1276, /UMR CNRS 8044, /EHESS/Paris), Paris, France.
Background: Opioid Use Disorder (OUD) often provokes dramatic consequences in terms of increased morbi-mortality. Two medications have mainly been worldwide used for OUD (MOUD), buprenorphine and methadone. Recently, however, some reports have highlighted the use of Morphine Sulfate (MS) mainly obtained without a prescription but used as MOUD by opioid users and especially People Who Inject Substances (PWIS).
View Article and Find Full Text PDFChild Abuse Negl
February 2025
Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP), Equipe de Recherche en Epidémiologie Sociale (ERES), 75571 Paris, Cedex 12, France.
Background: Intimate partner violence (IPV) is associated with children's emotional and behavioral difficulties. Psychological-IPV (P-IPV) is most common, and occurs alone or along other forms of IPV. Little is known about the longitudinal course of P-IPV exposure and its consequences on children taking into account whether or not they are present during parental arguments.
View Article and Find Full Text PDFDiabetes Metab
December 2024
Endocrinology-Diabetology-Nutrition, University of Bordeaux College of Health Sciences, Bordeaux 33000, France.
Since the pionneer work of Meerwaldt and the Groningen team, who related skin autofluorescence (SAF) to the dermal concentrations of advanced glycation end-products (AGEs), hundreds of articles have been devoted to its application in diabetes. Due to the slow turnover of the AGEs formed on collagen of the skin, the SAF can reflect the progressive accumulation of AGEs and hence be a marker of long-term glucose exposure. Accordingly, relations with HbA1c from the previous 3-10 years have been established in both type 1 and type 2 diabetes, and even in gestational diabetes mellitus.
View Article and Find Full Text PDFEClinicalMedicine
December 2024
Univ. Bordeaux, ISPED, Centre INSERM U1219, Bordeaux Population Health, Bordeaux F-33000, France.
The benefits of screening for cytomegalovirus (CMV) infection during pregnancy remain a topic of debate. To date, no randomized trial has compared the impact of screening versus routine management on the prevention of severe sequelae in newborns. Furthermore, it is unclear what actions can be taken in case of a positive screening given that there is limited evidence of effective interventions as no treatments showed significant effect on the frequency of congenital cytomegalovirus infections and, as additional challenge, the window for effective treatment initiation after maternal infection is narrow, estimated to be as short as five weeks.
View Article and Find Full Text PDFDrug Saf
December 2024
Service d'Audiologie and d'Explorations Otoneurologiques, Hospices Civils de Lyon, Lyon, France.
Introduction: Improving adverse events following immunisation (AEFI) detection is vital for vaccine safety surveillance, as an early safety signal can help minimize risks. In February 2022, the World Health Organization reported a preliminary signal on sudden sensorineural hearing loss (SSNHL) following coronavirus disease 2019 (COVID-19) vaccination, 54 million persons in France received at least one dose, covering 78.8% of the population within a year.
View Article and Find Full Text PDFRev Prat
November 2024
Université de Bordeaux, Inserm, BPH, U1219, Bordeaux, France.
EFFECTS OF AIR POLLUTION ON EYE HEALTH. In addition to its well-known effects on cardio-respiratory health, air pollution could also have an impact on eye health. Indeed, certain air pollutants, especially fine particles and nitrogen dioxide, can enter the bloodstream, triggering oxidative and inflammatory mechanisms involved in the development of the major eye diseases (glaucoma, age-related macular degeneration [AMD], cataracts).
View Article and Find Full Text PDFJ Clin Exp Neuropsychol
November 2024
Physical and Rehabilitation Medicine Department, University Hospital of Rennes, Rennes, France.
Geriatrics (Basel)
November 2024
Bordeaux Population Health Research Center, University of Bordeaux, INSERM U1219, 146 Rue Léo Saignat, F-33076 Bordeaux, France.
Background/objectives: A significant proportion of older adults with Alzheimer's disease or related disorders live in a long-term care facility. This study aimed to determine the time delay between admission and death for older adults with dementia.
Methods: A post hoc analysis was conducted using data from a French observational cohort, identifying older adults with dementia who were admitted to nursing homes.
Harm Reduct J
November 2024
INSERM, BPH, U1219, Mérisp/PHARES Team Labelled League Against Cancer, CIC 1401, University of Bordeaux, 33000, Bordeaux, France.
Context: Regular alcohol use is a predominant risk factor for disease, injury, and social harm. While robust evidence is advocating for implementing interventions to reduce the harms of illegal substance use, less literature is dedicated to identifying and understanding interventions aiming at reducing the various harms associated with alcohol.
Objectives: This review describes how alcohol harm reduction (AHR) interventions are currently conducted and analyzes the facilitators and barriers identified by the studies on their efficacy.
Glob Health Promot
November 2024
University of Bordeaux, INSERM, BPH, U1219, Mérisp/PHARES Equipe Labellisée Ligue Contre le Cancer, Bordeaux, France.
This article explores the role of population health intervention research (PHIR) in enhancing health promotion in France, stressing the importance of a more in-depth understanding and thorough analysis of healthcare interventions. Established in 2022, the So-RISP network aims to structure the PHIR field, consolidating expertise from renowned teams specializing in PHIR, primary cancer prevention, and addiction. In January 2023, So-RISP members convened a national workshop.
View Article and Find Full Text PDFEmerg Microbes Infect
December 2025
Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA
rVSVΔG-ZEBOV-GP and Ad26.ZEBOV, MVA-BN-Filo are WHO-prequalified vaccination regimens against Ebola virus disease (EVD). Challenges associated with measuring long-term clinical protection warrant the evaluation of immune response kinetics after vaccination.
View Article and Find Full Text PDFHarm Reduct J
November 2024
University of Bordeaux, INSERM, BPH, U1219, Mérisp/PHARES Team Labelled League Against Cancer, CIC 1401, Bordeaux, F-33000, France.
This article is part of Harm Reduction Journal's special issue on harm reduction research in the francophone context and specifically the Harm Reduction Network (HARENE). After highlighting the history and current context of harm reduction for women in France, we present the results of four research studies addressing the links between gender and drugs which were presented in the book Espaces genrés des drogues. Parcours dans la fête, l'intimité et la réduction des risques ('Gendered Spaces of Drugs.
View Article and Find Full Text PDFJ Hosp Infect
November 2024
HydroSciences Montpellier, IRD, CNRS, Montpellier University, Hospital Hygiene and Infection Control Department, University Hospital of Montpellier, Montpellier, France.
Lancet Microbe
November 2024
Centro de Investigação em Saúde de Manhiça, Manhiça, Mozambique; ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, Barcelona, Spain; Department of Preventive Medicine and Epidemiology, Hospital Clínic, Barcelona, Spain. Electronic address:
Background: There has been a global pursuit to improve the diagnosis of tuberculosis in young children by applying diagnostic methods on accessible biospecimens such as stool. We aimed to conduct a systematic review on the accuracy of stool-based molecular tests for tuberculosis diagnosis in children and to assess the impact of the available pre-processing methods and other design characteristics.
Methods: In this systematic review and meta-analysis, we evaluated studies in children younger than 16 years with presumptive tuberculosis that were published in English, Spanish, French, and Portuguese from Jan 1, 2000, to May 3, 2024, in MEDLINE, Embase, and Embase Classic, comparing the molecular detection of Mycobacterium tuberculosis DNA in stool with microbiological tests on other samples or a clinical diagnosis.
BMC Med Educ
November 2024
University Department of Public Health, Prevention, Observation, and Territories, Faculty of Health Simone Veil, University of Versailles St-Quentin-en-Yveline (UVSQ), Montigny-le-Bretonneux, France.
Vaccine hesitancy (VH) is an issue for healthcare students, influenced by safety concerns and misinformation. The need for better communication training and understanding sociocultural factors in VH was highlighted in a European University Alliance seminar. Practical exercises like simulation role-playing, interprofessional collaboration, and digital literacy may improve vaccine education.
View Article and Find Full Text PDFReprod Health
November 2024
INSERM U1219, Bordeaux Population Health Research, ISPED, University of Bordeaux, Bordeaux, France.
Background: Female Sex Workers (FSW) in Sub Saharan Africa face multiple challenges increasing their vulnerability to poor health, particularly poor sexual and reproductive (SRH) health outcomes and violence. The aim of this study was to assess the use of gynecology health care services and factors associated with its use as well as experiences of violence among FSW in Togo.
Method: A cross-sectional study was carried out in 2021 among FSW in two cities of Togo.
BMJ Open
November 2024
Service de prévention, CHU de Bordeaux, Bordeaux, France.
Introduction: In 2021, among French women who smoked when they knew they were pregnant, 59% still smoked at the end of pregnancy. Support for pregnant women to stop smoking must include a structured organisational perspective. The main objective of the study is to evaluate the effectiveness of the 5A-QUIT-N organisational intervention on smoking cessation at delivery among pregnant women who smoke during pregnancy.
View Article and Find Full Text PDFActa Ophthalmol
November 2024
Univ. Bordeaux, INSERM, BPH, U1219, Bordeaux, France.
BMJ Open
November 2024
Infectious Disease Epidemiology, Bernhard Nocht Institute of Tropical Medicine, Hamburg, Germany
Objectives: This study aims to identify the factors influencing vaccine hesitancy, willingness and its variation over time in order to inform more responsive strategies for increasing vaccination uptake. The specific objectives are: (1) to describe and compare levels of COVID-19 vaccine hesitancy among the general population in rural and urban settings in West Africa over time and (2) to identify factors associated with COVID-19 vaccination willingness and hesitancy among the general population across five West African countries over time.
Design: Following a baseline survey (Wave I), three serial cross-sectional surveys (Waves II-IV) were implemented.
Ther Adv Neurol Disord
October 2024
Department of Neurology, University of Regensburg, Universitätsstraße 84, Regensburg 93053, Germany.
Background: Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system affecting approximately 2.8 million people worldwide. In addition to genetic and environmental factors, various lifestyle factors contribute to disease development and progression.
View Article and Find Full Text PDFSci Total Environ
December 2024
Soil Physics and Land Management Group, Wageningen University & Research, the Netherlands.
J Thromb Haemost
October 2024
Hematology Laboratory, La Timone University Hospital of Marseille, Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, Marseille, France; Service de médecine vasculaire et Hypertension Artérielle, Faculté de Médecine de Marseille, Aix-Marseille Université, Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone, Marseille, France. Electronic address:
Background: The long-term recurrence risk after a pregnancy-associated venous thromboembolism (VTE) is sparsely assessed.
Objectives: To determine the rate of recurrence after a pregnancy-associated VTE and identify associated risk factors.
Methods: Five hundred eighty-seven women with a history of first VTE occurring during pregnancy or up to 3 months after delivery were referred to La Timone Hospital, Marseille, France.