3 results match your criteria: "Two Medical Center Dr.[Affiliation]"
Erratum to: Rpl22 is required for mRNA translation and meiotic induction in .
Cell Div
July 2017
Department of Molecular Biology, Rowan University School of Osteopathic Medicine, Two Medical Center Dr., Stratford, NJ 08055 USA.
[This corrects the article DOI: 10.1186/s13008-016-0024-3.].
View Article and Find Full Text PDFRpl22 is required for IME1 mRNA translation and meiotic induction in S. cerevisiae.
Cell Div
August 2016
Department of Molecular Biology, Rowan University School of Osteopathic Medicine, Two Medical Center Dr., Stratford, NJ 08055 USA.
Background: The transition from mitotic cell division to meiotic development in S. cerevisiae requires induction of a transient transcription program that is initiated by Ime1-dependent destruction of the repressor Ume6. Although IME1 mRNA is observed in vegetative cultures, Ime1 protein is not suggesting the presence of a regulatory system restricting translation to meiotic cells.
View Article and Find Full Text PDFAttenuation of antioxidative capacity enhances reperfusion injury in aged rat myocardium after MI/R.
Am J Physiol Heart Circ Physiol
December 2004
Dept. of Cell Biology, UMDNJ-School of Osteopathic Medicine, Two Medical Center Dr., Stratford, NJ 08084, USA.
Article Synopsis
- Mortality from ischemic cardiovascular diseases is higher in the elderly compared to young adults, with the study hypothesizing that this increased vulnerability is due to decreased antioxidative capacity in aged hearts after ischemia-reperfusion (MI/R) injury.
- Experiments with young (4-month-old) and aged (20-month-old) rats showed that young rats had greater signs of oxidative stress and inflammation after MI/R, indicated by higher leukocyte infiltration and myeloperoxidase activity.
- In contrast, aged rats displayed more severe reperfusion damage linked to lower antioxidative capacity, as shown by a decreased glutathione ratio, suggesting that aging affects the heart’s response to oxidative stress during reperfusion.