140 results match your criteria: "Tver State Medical University[Affiliation]"

was a systematic review of modern methods of three-dimensional cephalometric analysis, and the assessment of their efficiency. The scientific papers describing modern diagnostic methods of MFA in dental practice were searched in databases PubMed, Web of Science, eLIBRARY.RU, as well as in a searching system Google Scholar by the following key words: three-dimensional cephalometry, three-dimensional cephalometric analysis, orthodontics, asymmetric deformities, maxillofacial anomalies, 3D cephalometry, CBCT.

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Aim: To study the factors that influence the occurrence of postoperative atrial fibrillation (POAF) in patients with chronic ischemic heart disease (IHD) after coronary artery bypass grafting (CABG).

Material And Methods: This single-center prospective observational non-randomized study included 152 patients with chronic IHD. Mean age of patients was 64.

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Article Synopsis
  • Bismuth quadruple therapies (BQTs) have been effective in treating Helicobacter pylori infections in Europe, particularly in the face of antibiotic resistance, with notable use increasing from 8.6% in 2013 to 39% in 2021.
  • An analysis of data from nearly 50,000 patients indicated that the single-capsule BQT was the most common regimen and achieved over 90% effectiveness with certain combinations.
  • Key factors that improved treatment success included adherence to the regimen, use of high-dose proton pump inhibitors, and implementing the therapy as a first-line treatment.
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An overview of various cell engineering techniques being developed for modern conservative and reconstructive periodontology is presented. The accelerated development of cellular engineering technologies poses to medicine and, in particular, periodontics, the task of early implementation of the results of such experiments into patient management protocols. The main groups of promising techniques that are closest to practical healthcare are: isolation and use of stem cells; synthesis of biologically active (inductive) signaling molecules; development of scaffolds that ensure three-dimensional tissue growth.

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Aim: To evaluate the possibilities of post-processing of multidetector computed tomography (CT) results in the non-invasive diagnosis of pancreatic fibrosis (PF).

Materials And Methods: The study included 165 patients aged 57.91±13.

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Aim: To systematize data on the prevalence of gastroesophageal reflux disease (GERD) in the adult population of Russia.

Materials And Methods: The search for studies was conducted in the electronic databases MEDLINE/PubMed, EMBASE, and RSCI (Russian Science Citation Index) from January 2000 to December 2022. The review included relevant publications in peer-reviewed periodicals in English or Russian, publications with data from cross-sectional epidemiological studies assessing the prevalence of GERD in the Russian population, studies on adult patients with GERD, and publications with detailed descriptive statistics that allow using the data in the meta-analysis.

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  • The study aimed to investigate the role of immunological markers in patients with obstructive sleep apnea (OSA) and accompanying health issues by comparing two groups: one with OSA and one without.
  • Results showed higher levels of certain markers (GFAP, BDNF, antibodies to acetylcholine receptors) and indicators of depression and drowsiness in OSA patients, suggesting cognitive impairments linked to these markers.
  • The findings indicate that neuromarkers like GFAP and BDNF are associated with cognitive dysfunction in OSA, with elevated acetylcholine receptor antibodies possibly pointing to neuromuscular issues and emotional problems, particularly depression and fatigue, worsening as OSA severity increases.
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  • Prophages significantly influence the characteristics of pathogenic bacteria, yet their ecological and evolutionary roles, particularly in bacteria linked to gastric cancer, are not well understood.
  • A comprehensive analysis of 1,011 complete clinical genomes revealed that 29.5% contain prophages, with only 32.2% being complete, and their distribution varies by geography and ancestry but not by the disease status of hosts.
  • The study uncovered mechanisms of prophage inactivation and proposed a new model for regulating the lysogenic-lytic cycle, providing a deeper understanding of how prophages impact bacterial genetics and adaptation.
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  • * A study evaluated a new Sanger sequencing test on 25 pure culture samples, showing 100% sensitivity for clarithromycin and high sensitivity (93%) and specificity (92%) for levofloxacin resistance detection.
  • * In clinical tests on 112 patients, resistance mutations were found in 24% for clarithromycin and 23% for levofloxacin, with specific mutations identified, emphasizing the importance of personalized therapy to combat antibiotic resistance.
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Indications of Helicobacter pylori Eradication Treatment and Its Influence on Prescriptions and Effectiveness (Hp-EuReg).

Helicobacter

July 2024

Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Hospital Universitario de La Princesa, Universidad Autónoma de Madrid (UAM), Madrid, Spain.

Article Synopsis
  • A study examined how different reasons for testing for Helicobacter pylori (H. pylori) affect treatment prescriptions and their success rates across Europe from 2013 to 2023.
  • Out of 53,636 cases, the most common reasons for testing included dyspepsia with normal endoscopy and various types of ulcers, with treatment effectiveness ranging from 87% to 91% based on the indication.
  • Patients with ulcers and preneoplastic lesions experienced higher treatment success and compliance, while those tested for dyspepsia had higher rates of adverse effects.
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Background: This study aimed to evaluate post-operative outcomes by comparing factors such as post-operative pain, duration of hospitalization, time needed to resume normal and full activities, and complications between laparoscopic total extraperitoneal (TEP) and Lichtenstein tension-free mesh hernioplasty or repair (LMR) for inguinal hernias.

Materials And Methods: A prospective study was conducted involving male patients undergoing either LMR or laparoscopic TEP mesh repair, with 30 patients in each group. The study assessed post-operative pain, duration of hospital stay, return to normal activities, and complications.

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Atrial fibrillation (AF) is the most common heart rhythm disorder in clinical practice. It worsens the quality of life of patients, leads to an increase in the mortality rate because of its association with a high risk of thromboembolic complications. The current pandemic of a new coronavirus infection, which began in March 2020, was marked by an increase in cardiovascular diseases, including an increase in the number of patients with AF.

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Role of compliance in Helicobacter pylori eradication treatment: Results of the European Registry on H. pylori management.

United European Gastroenterol J

July 2024

Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Universidad Autónoma de Madrid (UAM), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.

Background: Adherence to Helicobacter pylori (H. pylori) eradication treatment is a cornerstone for achieving adequate treatment efficacy.

Objective: To determine which factors influence compliance with treatment.

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History of chronic gastritis: How our perceptions have changed.

World J Gastroenterol

April 2024

Department of Internal Medicine and Gastroenterology, Omsk State Medical University, Omsk 644099, Russia.

Currently, the diagnostic strategy for chronic gastritis (CG) is aimed not just at fixing the presence of gastric mucosal inflammation, but also at gastric cancer (GC) risk stratification in a particular patient. Modern classification approach with the definition of the stage of gastritis determines the need, activities and frequency of dynamic monitoring of a patient. However, this attitude to the patient suffering from CG was far from always.

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Aim: To study the relationship between changes in left atrial volume (LAV) during exercise and the result of a diastolic stress test (DST) in patients with arterial hypertension (AH).

Material And Methods: The study included 219 patients with AH without ischemic heart disease and atrial fibrillation. During the DST performed before and after exercise, the ratio of transmitral flow velocity to mitral annular velocity (E/e'), the left atrial global longitudinal strain in the reservoir phase (reservoir strain), and LAV were determined.

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Background & Aims: Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology and manifestations. Our aims were to characterize type 1 AIP in a large pan-European cohort and study the effectiveness of current treatment regimens.

Methods: We retrospectively analyzed adults diagnosed since 2005 with type 1 or not-otherwise-specified AIP in 42 European university hospitals.

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Role of proton pump inhibitors dosage and duration in Helicobacter pylori eradication treatment: Results from the European Registry on H. pylori management.

United European Gastroenterol J

February 2024

Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Universidad Autónoma de Madrid (UAM), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.

Article Synopsis
  • - The management of Helicobacter pylori infection involves a combination of proton pump inhibitors (PPIs) and antibiotics to effectively eradicate the bacteria, as evaluated by the European Registry on Helicobacter pylori management (Hp-EuReg).
  • - Analysis of data from 36,579 patients across five countries revealed that 14-day treatments with specific antibiotic combinations and high-dose PPIs resulted in optimal effectiveness, while 10- and 14-day therapies with high-dose PPIs were also successful.
  • - The study concludes that for first-line treatment, the use of high-dose PPIs is recommended, especially in certain combinations and durations, while shorter 7-day therapies showed suboptimal results.
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Effectiveness of Helicobacter pylori Treatments According to Antibiotic Resistance.

Am J Gastroenterol

April 2024

Gastroenterology Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Universidad Autónoma de Madrid (UAM), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.

Article Synopsis
  • Antibiotic resistance significantly affects the treatment success rates for Helicobacter pylori infections, with noted resistance levels in Europe.
  • A study analyzed 2,852 naive patients and found that the 3-in-1 single capsule with bismuth, metronidazole, and tetracycline, as well as a quadruple therapy with bismuth, had the highest effectiveness against H. pylori, even with existing resistances.
  • For non-naive patients, resistance was even higher, but the same 3-in-1 capsule and triple therapy with levofloxacin showed promising results, highlighting the need for effective treatment options based on resistance patterns.
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Glaucoma is a severe, rapidly progressing disease that in the absence of proper treatment leads to blindness in 20% of patients. According to the World Glaucoma Association, this disease is the most socially significant in modern ophthalmology and requires searching for new and effective methods of treatment. This article presents the results of research and reviews on this issue, considers both conservative therapy and surgical methods of treatment, analyzes in detail modern methods of micro-invasive eye surgery actively used in clinical practice.

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The prevalence of Helicobacter pylori remains high in the older population. Specific age-related peculiarities may impact the outcomes of H. pylori treatment.

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European countries of "Eastern Block" origin took different healthcare and economic development trajectories after the Berlin Wall fell. Despite decreased maternal and neonatal mortality in the last two decades, healthcare disparities exist between the various countries. Minimum standards for obstetric anesthesia are not available for every maternity patient.

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  • The study investigates the relevance of biopsies from the incisura angularis in determining the risk of gastric cancer in patients with chronic gastritis using the OLGA system for assessment.
  • A total of 718 patients were examined, aged 20 to 84, and categorized based on the presence of autoimmune gastritis markers, resulting in three distinct patient groups.
  • Results showed that grade II inflammatory changes were prevalent (72.3%) across all groups, with severe chronic gastritis activity most common in patients with non-autoimmune gastritis, and these findings remained consistent even when excluding the incisura angularis biopsy.
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The segmentation of patients into homogeneous groups could help to improve eradication therapy effectiveness. Our aim was to determine the most important treatment strategies used in Europe, to evaluate first-line treatment effectiveness according to year and country. : All first-line empirical treatments registered at AEGREDCap in the European Registry on management (Hp-EuReg) from June 2013 to November 2022.

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Unlabelled: The prevalence of periodontal diseases is increasing, tends to increase with age and is considered as one of the main causes of tooth loss. To assess the effectiveness of new methods of treatment of periodontal diseases, studies on laboratory animals can be promising.

The Aim Of The Study: to develop a new method of accelerated modeling of experimental periodontitis on laboratory animals.

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