Experiences of Intern Nurses Returning From Distance Education to Clinical Practice During the COVID-19 Pandemic: A Qualitative Study.

Rationale: The present study aimed to understand the experiences of intern nurses returning to clinical practice after a year-long distance education during the pandemic.

Methods: The study was conducted using the qualitative content analysis method. The participants were 32 intern nurses.

Nurses' Alarm Fatigue Levels in Adult Intensive Care Units and Their Strategies to Reduce Fatigue: A Convergent Parallel Design.

Background: Alarm fatigue is a challenge for nurses and patients. Also, feasible strategies to reduce/manage alarm fatigue are still unclear.

Aim: This study aimed to identify adult intensive care nurses' alarm fatigue levels and strategies to reduce alarm fatigue.

The impact of bifurcation angle on clinical outcomes in patients who underwent nano-crush technique: the insight from the multicenter EVOLUTE-CRUSH V study.

Background: This multicenter study aimed to retrospectively assess the relationship between bifurcation angle (BA) and major cardiovascular events (MACEs) in patients undergoing nano-crush technique (NCT) for complex bifurcation lesions (CBLs).

Methods: A total of 122 consecutive patients [male: 85 (69.6%), mean age: 61.

Evaluation of Retinal and Choroidal Microvascularity in Patients with Benign Essential Blepharospasm.

Purpose: To assess the retinal and choroidal microvascular changes in patients with benign essential blepharospasm (BEB) and to investigate the factors that may be effective on microvascularity.

Methods: This study included patients with BEB and healthy controls. All participants underwent a comprehensive examination followed by optical coherence tomography angiography (OCTA).

Sleep hygiene education in older adults: effectiveness and association with comprehensive geriatric assessment.

Objectives: This study aimed to evaluate the results of sleep hygiene education via a comprehensive geriatric assessment.

Method: A cross-sectional research was conducted on insomnia outpatients at a tertiary hospital, and all participants received sleep hygiene education as well as a comprehensive geriatric assessment. Sleep parameters were assessed before and four weeks after education.

Comprehensive Analysis of the Antioxidant and Enzyme Inhibitory Properties and Phenolic Compounds of Phlomis armeniaca: Potential Applicant in Neurodegenerative Diseases.

This study investigates the antioxidant and enzyme inhibitory properties of Phlomis armeniaca, a perennial plant native to the eastern and southeastern regions of Türkiye. Ethanol extracts of the plant were analyzed using various bioanalytical methods, including Fe³⁺-Fe²⁺ reducing power, CUPRAC, DPPH, and ABTS radical scavenging activities, as well as total phenolic and flavonoid content assessments. The results showed that Phlomis armeniaca is rich in phenolic (38.

Impact of water stress to plant epigenetic mechanisms in stress and adaptation.

Water is the basic molecule in living beings, and it has a major impact on vital processes. Plants are sessile organisms with a sophisticated regulatory network that regulates how resources are distributed between developmental and adaptation processes. Drought-stressed plants can change their survival strategies to adapt to this unfavorable situation.

Direct observation of small molecule activator binding to single PR65 protein.

The reactivation of heterotrimeric protein phosphatase 2A (PP2A) through small molecule activators is of interest to therapeutic intervention due to its dysregulation, which is linked to chronic conditions. This study focuses on the PP2A scaffold subunit PR65 and a small molecule activator, ATUX-8385, designed to bind directly to this subunit. Using a label-free single-molecule approach with nanoaperture optical tweezers (NOT), we quantify its binding, obtaining a dissociation constant of 13.

Assessment of complications and success rates of Percutaneous nephrolithotomy: single tract . multi tract approaches.

Purpose: The objective of this study was to assess the success and complication rates of single-tract access . multi-tract percutaneous nephrolithotomy (PNL).

Material And Methods: The medical records of consecutive patients who underwent PNL for staghorn, partial staghorn, and complex kidney stones between 2014 and 2022 were retrospectively reviewed.

The effectiveness of arbuscular mycorrhizal fungal species (, , and ) in the biocontrol of root and crown rot pathogens, and mixture in pepper.

This study evaluated the effectiveness of arbuscular mycorrhizal fungi (AMF) species, including (FM), (RI), (CE), and a Mycorrhizal mix (MM) comprising these three species, on pepper plants ( L.) inoculated with two isolates of (48- and 18-) and two isolates of mix (50-F. mixture and 147-F.

SL70, a Novel Exopolysaccharide Producer from Traditional Sourdough Fermentation of Einkorn ( L. ssp. ).

Research Background: Given the potential of microbial exopolysaccharides from lactic acid bacteria in various industrial processes, alternative sources for the isolation of lactic acid bacteria are highly topical. In this study, we used a traditional sourdough from einkorn ( L. ssp.

Quince Powder Increases Antioxidant Activity and Probiotic Survival in Yoghurt.

Research Background: In recent years, there has been a growing interest in incorporating fruit-based additives into yogurt formulations as a means to improve the functionality of the product. This study aims to produce a functional product by incorporating quince, which is rich in fibre, vitamins, minerals and antioxidant activity, into a yoghurt formulation.

Experimental Approach: The influence of the addition of quince powder (0 (control), 0.

Autonomous learning and creative cognition: the mediating effect of gifted students' self-efficacy.

Introduction: In today's world, it is of great importance to raise qualified learners whose creative thinking skills and self-efficacy are developed and who can make various choices and take responsibility for their choices as well as implementing them by making their own decisions. In this regard, the study examined the role of gifted students' self-efficacy (SE) as a mediator on the relationship between autonomous learning (AL) and creative cognition (CC).

Methods: A proposed conceptual model was tested using a cross-sectional survey design.

A Multicenter ICET-A Survey on Adherence to Annual Oral Glucose Tolerance Test (OGTT) Screening in Transfusion-Dependent Thalassemia (TDT) Patients - The Expert Clinicians' Opinion on Factors Influencing the Adherence and on Alternative Strategies for Adherence Optimization.

Background: Current guidelines for screening glucose dysregulation (GD) in patients with transfusion-dependent thalassemia (TDT) recommend an annual 2-hour oral glucose tolerance test (OGTT) starting at the age of 10 years.

Objective: Assessment of adherence to OGTT screening in patients with TDT.

Methods: A questionnaire was distributed to 18 Thalassemia Centers in 10 different countries, targeting factors influencing adherence to annual OGTT screening in specialized multidisciplinary pediatric and adult TDT units and identifying strategies to improve adherence to OGTT in TDT patients.

Evaluating YouTube Videos With Prophylactic Mastectomy Content in Terms of Their Quality and Reliability.

Purpose of this study is to investigate the quality and reliability of YouTube video contents on prophylactic mastectomy. The search terms "prophylactic mastectomy," "prophylactic mastectomy surgery," "preventive surgery for breast cancer," "risk-reducing mastectomy," and "prophylactic mastectomy and breast reconstruction" were searched on YouTube. The uploader, video content, length (seconds), upload date, number of days since upload date, number of views, number of comments, and likes were recorded and evaluated.

Association of NOX5 Expression with Sperm Activity and Motility in Pathospermic Infertile Men.

Background: The newest NOX isoform, NOX5, has been found in mammalian spermatozoa. Many physiological and pathological situations in spermatozoa are mediated by reactive oxygen species (ROS). NOX5 is the main source of ROS in spermatozoa.

Green hydrothermal approach for the synthesis of carbon quantum dots from waste tea bags for acrylamide detection in drinking water: A fluorescence assay validated by HPLC-PDA analysis.

The study focused on converting tea bag waste into strong fluorescence carbon quantum dots (TBW-CQDs) for the detection of acrylamide in drinking water, antimicrobial activity, and photocatalytic degradation. The TBW-CQDs exhibited blue luminescence and maximum absorbance at 287 nm under UV light and distinctive fluorescence emission and excitation wavelengths at 425 nm and 287 nm, respectively. TBW-CQDs revealed a particle size of 8.

Next-Generation Carbazole-Linked 1,2,4-Triazole-Thione Derivatives: Strategic Design, Synthesis, Molecular Docking, and Evaluation of Antidiabetic Potential.

Currently, available therapies for diabetes cannot achieve normal sugar values in a high percentage of treated patients. This work synthesized a series of carbazole-triazole-thione derivatives, and their potential antidiabetic activity was investigated against the key diabetic enzymes α-amylase and glycosidase. Normal human hepatic stellate cells (LX-2) were employed to assess their cytotoxicity and safety, followed by in vivo testing to investigate the hypoglycemic effect of the most promising agent.

Preparation and Characterization of the MMT@FeO@Ag Nanocomposite for Catalytic Degradation of Methyl Yellow: Reaction Parameters and Mechanism Based on the Artificial Neuron Network.

The montmorillonite@iron oxide@silver (MMT@FeO@Ag) nanocomposite, which is recyclable and exhibits high catalytic activity, was evaluated for the degradation of methyl yellow (MY), a carcinogenic azo dye. For this purpose, MMT@FeO was first synthesized via the coprecipitation method and then Ag was doped to MMT@FeO via the chemical reduction method. MMT, MMT@FeO, and MMT@FeO@Ag were characterized by various techniques including scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, vibrating sample magnetometer, and thermal gravimetric analysis.

Novel Electrochemical Approaches for Anticancer Drug Monitoring: Application of CoS@Nitrogen-Doped Amorphous Porous Carbon Composite in Nilotinib Detection.

A novel composite containing CoS and nitrogen-doped amorphous porous carbon (NAPC), denoted as CoS@NAPC, was successfully synthesized from a mixture of cobalt-based ZIF-12 and sulfur through one-pot pyrolysis. The morphology and microstructure of the composites are evaluated with appropriate spectroscopic techniques. CoS@NAPC was used to modify the glassy carbon electrode (GCE) to detect Nilotinib.

Novel Enyne-Modified 1,4-Thiazepines as Epidermal Growth Factor Receptor Inhibitors: Anticancer and Computational Studies.

1,4-Thiazepines (TZEPs) featuring enyne modifications represent promising candidates in cancer therapy. We synthesized novel TZEP derivatives and assessed their cytotoxicity, apoptosis induction, EGFR inhibition, and molecular interactions. TZEPs exhibited cytotoxic effects against cancer cell lines, with compounds TZEP6 and TZEP7 showing significant activity.

Effect of Polycaprolactone, Zinc Oxide, and Poly(ethylene glycol) on the Properties of Polylactic Acid Composite Fibers Obtained by Melt Electrospinning.

Polylactic acid (PLA) composite fibers were obtained using melt electrospinning, in which a high voltage was applied to the nozzle of the 3D printer. Filaments for melt electrospinning were prepared by using an extruder operated at 155 °C. PLA was mixed with polycaprolactone (PCL; 95:5, 90:10, and 85:15 by wt %), zinc oxide (ZnO; 0.

Shape Memory PLA/TPU Blend Using High-Speed Thermo-Kinetic Mixing.

In this study, a thorough examination of the chemical, thermal, and mechanical characteristics, as well as shape memory behavior at low temperatures, of blends consisting of polylactic acid (PLA) and polyurethane (TPU) is conducted. The research involves the preparation of PLA/TPU mixtures with varying concentrations of TPU using a high-speed thermo-kinetic mixing approach. Chemical, morphological, and thermal analyses were conducted on pure PLA, TPU, and PLA/TPU mixtures by using Fourier Transform Infrared (FTIR), X-ray diffraction pattern spectroscopy (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), and dynamic mechanical analysis (DMA).

Tuning the Photophysical Properties of BODIPY Dyes and Studying Their Self-Assembly via Hydrogen Bonding.

Here, BODIPY derivatives were functionalized with barbituric acid, which has multiple hydrogen bonding abilities that are directional, to have highly ordered hydrogen bond-mediated self-assembled structures to tune BODIPY's photophysical properties. The synthesis of barbituric acid-functionalized BODIPY derivatives via Vilsmeier and Knoevenagel reactions was achieved, and the resulting compounds were characterized with FT-IR, H NMR, C NMR spectroscopy, and mass spectrometry. Hydrogen bond-mediated self-assembled structures were investigated through UV-vis and fluorescence spectrophotometry, H NMR spectroscopy, and a dynamic light scattering method in solution.