Machine Learning in Optimising Nursing Care Delivery Models: An Empirical Analysis of Hospital Wards.

Objective: This study aims to assess the performance of machine learning (ML) techniques in optimising nurse staffing and evaluating the appropriateness of nursing care delivery models in hospital wards. The primary outcome measures include the adequacy of nurse staffing and the appropriateness of the nursing care delivery system.

Background: Historical and current healthcare challenges, such as nurse shortages and increasing patient acuity, necessitate innovative approaches to nursing care delivery.

Quantification of Agnuside in Human Plasma with a Novel High-Performance Liquid Chromatographic Method and Pharmacokinetic Study.

This study presents a combination of High Performance Liquid Chromatography (HPLC) and ultraviolet (UV) detection that provides the quantification of agnuside in human plasma specimens. Reverse-phase chromatographic separation was carried out with C18 column (150 mm × 4.6 mm × 5 μm), at 25°C with isocratic elution of the mobile phase containing methanol: 0.

The effect of neoadjuvant chemotherapy on survival outcomes in patients with variant histologies who underwent radical cystectomy with precystectomy diagnostic accuracy: A multicenter study of the Turkish Urooncology Association.

Objectives: To evaluate the role of neoadjuvant chemotherapy in the final treatment plan and its impact on survival in bladder cancer patients who were diagnosed with variant histology in the radical cystectomy specimen and whose diagnostic accuracy was achieved with the previous transurethral resection of the bladder specimen.

Methods: In this retrospective multicenter study, data from 221 patients across 9 centers were analyzed between January 2012 and January 2022. The primary endpoint was overall, cancer-specific, recurrence-free, and metastasis-free survival rates among patients with and without neoadjuvant chemotherapy, and the secondary endpoint was to identify independent predictors of survival.

Intraoperative impedance and ECAP results in cochlear implant recipients with inner ear malformations and normal cochlear anatomy: a retrospective analysis.

Background: The intraoperative measurements are essential steps in cochlear implant (CI) surgery for confirming correct electrode placement.

Objectives: To examine the intraoperative impedance and electrically evoked action potential (ECAP) measurement results of cochlear implant (CI) users with normal cochlear anatomy (NCA) and to compare them with CI users with inner ear malformations (IEM).

Material And Methods: This retrospective study included intraoperative data of 300 ears from 258 individuals using Medel and Cochlear (Nucleus) CI devices.

Potassium-Rich, Gluten-Free Diets for Patients with Sjögren's Syndrome: A Hypothesis.

Sjögren's syndrome (SS) is an autoimmune disease and its management is palliative. There is no specific dietary protocol for SS patients. A gluten-free diet has been tested in SS patients with celiac disease (CD) and indicated modest improvements.

Elucidating the Biological Potential and DNA Protective Activities of Astragalus tokatensis Fisch: GC-MS and LC-HRMS-based Characterization and Molecular Docking Studies.

Astragalus tokatensis is a local endemic species and no study exists on this species. In this study, hexane, dichloromethane, methanol and water extracts were obtained from the parts of root, leaf and flower of A. tokatensis.

Differences and Similarities Between Children and Adults With Rhupus Syndrome.

Aim: In this study, we aimed to evaluate and compare the characteristics of pediatric and adult rhupus patients.

Methods: Thirty pediatric patients with rhupus syndrome and 15 adult patients with rhupus syndrome were included in this study. Similarities and differences between both groups were evaluated.

Determining the Mental Health Literacy Level of University Students and Examining Their Attitudes Towards Seeking Psychological Help.

This descriptive study examined the mental health literacy levels and attitudes towards seeking psychological help among university students. The study was conducted with 317 students from a university in Türkiye. Data were collected via an online platform using a Personal Information Form, the Mental Health Literacy Scale (MHLS) and the Attitudes Toward Seeking Professional Psychological Help Scale-Short Form (ATSPPHS-SF).

Nanobubble Ozone Stored in Hyaluronic Acid-Decorated Liposome Solutions: Inactivating Antibiotic-Resistant Bacteria and Genotoxicity, Sub-Acute and Sub-Chronic Toxicity Tests.

Introduction: Nanobubble ozone stored in hyaluronic acid-decorated liposomes (patent application PCT/TR2022/050177) was used, and the Minimum Inhibitory Concentration (MIC) was found to be 1562 ppm. (patient isolate), (patient isolate), (MRSA) (ATCC12493), and (ATCC25922) bacteria, which are hospital-acquired and healthcare-associated infections, were used. A time-dependent efficacy study was conducted at 1600 ppm.

Late Presentation of Congenital Aqueduct Stenosis in Adulthood with High-Riding Basilar Artery: Case Report.

 A rare variant of congenital aqueductal stenosis (CAS) is known as adult-onset CAS, characterized by the emergence of symptoms during adulthood.  A 35-year-old man presented complaining of acute-onset headache and vomiting. Magnetic resonance imaging of the brain revealed an acute hydrocephalus due to an aqueductal web.

Phytochemical investigation and assessment of the anti-inflammatory activity of four taxa growing in Turkey.

Introduction: L. has been known as "hogweed" and used for inflammatory diseases, including fever, enteritis, and bronchitis, for many years worldwide. The genus is also prominently recognized for its high content of coumarins, which are considered a significant group of natural compounds known for their noteworthy anti-inflammatory properties.

The relationship between steroid treatment and mortality in patients with COVID-19 followed up in an intensive care unit.

Aim: Optimal treatment of the coronavirus disease (COVID-19) is still unclear. It has been reported that the use of different doses of corticosteroid treatments may reduce mortality. In our study, we aimed to find the effect of corticosteroid treatment dose on mortality of patients followed up in intensive care due to COVID-19.

Performance analysis of a wavy fin-and-tube automobile radiator operating on ethylene glycol and water based ternary nanofluids.

Efficient thermal management is crucial for optimizing the performance and longevity of automotive engines, particularly as environmental regulations become more stringent and consumer demand for fuel efficiency increases. This paper investigates the energy and exergy performance of a wavy fin-and-tube radiator employing novel ternary nanofluids (TNFs) for enhanced automotive cooling. A theoretical comparative analysis was performed on four distinct ethylene glycol-water solution-based TNF configurations.

Free vibration and buckling analysis of axially functionally graded tapered Timoshenko beams using B-spline-based isogeometric analysis.

This study considers Timoshenko beam theory and the isogeometric analysis method to investigate the free vibration and buckling of axially functionally graded (AFG) tapered beams. The governing equations are obtained from the kinematic assumptions of Timoshenko beam theory and Hamilton's principle. The isogeometric analysis approach is implemented to solve the motion equations.

Predictive performance of noninvasive factors for liver fibrosis in severe obesity: a screening based on machine learning models.

Objectives: Liver fibrosis resulting from nonalcoholic fatty liver disease (NAFLD) and metabolic disorders is highly prevalent in patients with severe obesity and poses a significant health challenge. However, there is a lack of data on the effectiveness of noninvasive factors in predicting liver fibrosis. Therefore, this study aimed to assess the relationship between these factors and liver fibrosis through a machine learning approach.

H syndrome with bilateral choroidal osteoma: Coincidence or association?

Purpose: To report a case with bilateral corneal arcus and bilateral choroidal osteoma associated with H syndrome.

Methods: Descriptive case report.

Results: A 16-year-old girl with H syndrome was followed up in the pediatric nephrology clinic for chronic renal failure and was consulted to the ophthalmology clinic.

Bullying Among Special Education Students.

The purpose of the study is to examine traditional and cyberbullying among the students with special education needs attending special education schools. Additionally, traditional and cyber victimization among special education students have been examined in terms of gender and grade levels. A sample of the present study consists of 295 students with special education needs (177 gifted, 118 deaf) attending segregated special education schools.

The effects of warming on loggerhead turtle nesting counts.

Global trends in marine turtle nesting numbers vary by region, influenced by environmental or anthropogenic factors. Our study investigates the potential role of past temperature fluctuations on these trends, particularly whether warmer beaches are linked to increased nesting due to higher female production (since sea turtles have temperature-dependent sex determination). We selected the loggerhead turtle (Caretta caretta) due to its wide distribution, strong philopatry and vulnerability to environmental changes.

Synthesis of new dihydropyrimidine derivatives and investigation of their antimicrobial and DNA gyrase inhibitory activities.

Quinolone antibiotics are known for their antibacterial activity by inhibiting the enzyme DNA gyrase. Inspired by their mechanism, new compounds combining 1,4-dihydropyrimidine, a quinolone isostere, with pyridine/pyrimidine rings were synthesized. These derivatives showed antibacterial effects, likely through DNA gyrase inhibition, as supported by molecular docking and dynamics simulations.

Validity and Reliability of the Turkish Version of the Maternal Ambivalence Scale.

Aim: The aim of this study was to adapt the Maternal Ambivalence Scale (MAS) to Turkish culture and to conduct validity and reliability studies.

Design: The sample of the methodological type consisted of women (n = 302) who applied to the outpatient clinics of a university hospital in the north of Türkiye.

Methods: The data of the study were collected with the Personal Information Form, Depression Anxiety Stress Scale-21 and MAS.

Analgesic efficacy of the external oblique intercostal fascial plane block on postoperative acute pain in laparoscopic sleeve gastrectomy: a randomized controlled trial.

Background: Laparoscopic sleeve gastrectomy (LSG) causes significant postoperative pain, necessitating effective multimodal analgesia strategies. This study evaluated the efficacy of the external oblique intercostal block (EOIB) in this context.

Methods: This prospective, randomized, controlled, single-blind study conducted between April and December 2023 included 60 patients who underwent LSG.

Surgical fear and sleep quality effect the postoperative quality of recovery in patients undergoing brain tumor surgery: cross sectional study.

Background: Patients with a brain tumor experience high levels of anxiety because of the fear of remaining functional and neuropsychological sequelae. This situation affects the postoperative quality of recovery. This study was conducted to determine the effect of surgical fear and sleep quality on the postoperative quality of recovery and pain.

Impact of clinical pharmacist integration on diabetes management: a prospective cohort.

Introduction: Diabetes is a chronic disease with increasing prevalence. There is growing evidence pharmacist can contribute to clinical outcomes. This study aims to evaluate contribution of pharmacist to prediabetes and diabetes care.

Lasater clinical judgment rubric in nursing education: a Turkish validity and reliability study.

Introduction: Gaining clinical judgment competence among student nurses is a significant outcome of nursing education. In this education process, an assessment tool based on observable behaviors is needed for evaluating students' clinical judgment skills.

Objective: This study aimed to evaluate the validity and reliability of the Turkish version of the Lasater Clinical Judgment Rubric, which assesses student nurses' stages of clinical judgment competency in simulation-based education.