Ultrasonographic accuracy in evaluating response of clipped lymph nodes in targeted axillary dissection in breast cancer.

This study aimed to evaluate the diagnostic accuracy of ultrasonography in assessing the response of clipped axillary lymph nodes to neoadjuvant chemotherapy. Between February 2022 and September 2023, 43 patients who underwent axillary lymph node marking for targeted axillary dissection were retrospectively analyzed. Ultrasonography parameters such as the number, size, shape, cortical thickness, hilum status, and treatment response of the clipped lymph node were assessed.

The Role of Diet, Glycaemic Index and Glucose Control in Polycystic Ovary Syndrome (PCOS) Management and Mechanisms of Progression.

Purpose Of Review: Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder with several causal pathways including impaired glucose tolerance, insulin resistance (IR), compensatory hyperinsulinemia and excess androgens (hyperandrogenism). This heterogeneous condition causes a range of reproductive, metabolic and psychological implications, the severity of which can differ between individuals depending on factors such as age, diet, ethnicity, genetics, medication, contraceptive use, adiposity, and Body Mass Index (BMI).

Recent Findings: Dietary interventions that focus on a low glycaemic index and glucose control are an efficient first-line dietary solution for the management of impaired glucose tolerance and IR, which subsequently improves weight management, quality of life and PCOS-related symptoms in individuals with this condition.

Comparison of single-catheter with two-catheter concept in older female patients undergoing transradial coronary angiography.

Background: The aim of this study was to compare the efficacy outcomes of the traditional Judkins left and right catheters with those of the recently introduced Tiger catheter in female participants aged 65 years and older who underwent transradial coronary angiography.

Methods: A cohort of 160 female patients aged 65 and older who were scheduled for coronary angiography (CAG) were divided into two groups according to the use of Tiger (n = 80) or Judkins (n = 80) catheters for radial angiography at a ratio of 1:1, respectively. We analyzed the effectiveness of the Tiger and Judkins catheters, the incidence of catheter failure, contrast volume, CAG time, fluoroscopy time, dose-area product (in mGy/cm), and the occurrence of radial spasm.

Ambulatory blood pressure profiles of children with asthma compared to healthy controls.

Background: Studies suggest that asthma and hypertension may be comorbid conditions. Most of these studies are epidemiological research. However, data on the relationship between asthma and hypertension in childhood are limited.

Exploring the effects of perceived social support and psychological distress through mediation and multigroup analyses in work-related quality of life.

Work-related quality of life has emerged as a central focus in the field of occupational health due to its impact on individual well-being and overall quality of life. So, it is crucial to enhance the current theory by conducting a study on the concept across different sectors. Also, the specific mechanisms through which perceived social support influences work-related quality of life remain underexplored.

Upshot of Some Bioactive Compounds on Angiogenesis in Retinal Pigment Epithelial Cells.

Nowadays, the use of monoclonal antibodies to target angiogenic signalling pathways is common, but, unfortunately, the clinical activity of these agents is limited. Thus, the development of approaches targeting multiple pathways for anti-angiogenic effect will lead to increase the clinical benefit. For this purpose, oleuropein, hesperidin, piperine, proanthocyanidins and retinoic acid, which have previously been proven to be bioactive components, anti-angiogenic performances were experimentally tested in retinal pigment epithelial cells.

EEFSEC deficiency: A selenopathy with early-onset neurodegeneration.

Inborn errors of selenoprotein expression arise from deleterious variants in genes encoding selenoproteins or selenoprotein biosynthetic factors, some of which are associated with neurodegenerative disorders. This study shows that bi-allelic selenocysteine tRNA-specific eukaryotic elongation factor (EEFSEC) variants cause selenoprotein deficiency, leading to progressive neurodegeneration. EEFSEC deficiency, an autosomal recessive disorder, manifests with global developmental delay, progressive spasticity, ataxia, and seizures.

Novel smart materials with high curie temperatures: EuDyGeO, EuLaGeO and EuHoGeO.

The EuDyGeO, EuLaGeO and EuHoGeO powder were obtained through a solid-state reaction method via multistep firing of stoichiometric ratios of EuO, GeO, DyO, LaO and HoO in open atmosphere at temperatures from 800 to 1150 °C. The thermal behaviour, phase formation, SEM/EDX analysis, photoluminescence properties, Curie tempereture, dielectric and piezoelectric properties of the samples were investigated by TG/DTA, XRD, SEM, PL, TG/DTA, LCR-meter and d-meter, respectively. The germenates having triclinic crystal system have D→F, D→F, D→F, D→F transitions of Eu ions.

Comparative analysis of long versus short co-incubation of gametes on post-insemination outcomes and embryo morphokinetics.

Research Question: Does a short co-incubation of gametes in conventional IVF affect post-insemination outcomes and embryo morphokinetics?

Design: Sibling oocyte randomized pilot study conducted between December 2020 and March 2023. Eligible couples (n = 55) were women aged 18-43 years with BMI 35 km/m or lower and male normal semen parameters. Cumulus oocyte complexes (COC) (six to 12) were randomized in a 1:1:2 proportion in long (16-18 h) or short (2 h) co-incubation IVF exposure and ICSI, respectively.

Impacts of microplastic accumulation in aquatic environment: Physiological, eco-toxicological, immunological, and neurotoxic effects.

The presence of microplastics (MPs) in aquatic ecosystem has become a pressing global concern. MPs pose a significant threat to aquatic ecosystems, with devastating consequences for both aquatic life and human health. Notably, freshwater ecosystems are particularly vulnerable to MPs pollution.

Factors affecting behaviors during complementary feeding in infants and children aged 6-24 months.

The process that begins around the 6th month of life and continues until the 24th month is called the complementary feeding period. During this period, infants and children start receiving foods that complement breast milk or formula for the first time. The psychosocial factors the infants and children encounter during this period may affect their growth and health in later life.

Variability of Psoriatic Arthritis Impact of Disease questionnaire (PsAID12) thresholds in psoriatic arthritis: data from the ReFlaP study.

Objectives: To explore thresholds for the Psoriatic Arthritis (PsA) Impact of Disease questionnaire (PsAID12) score against disease activity measures in an observational setting, in patients with PsA.

Methods: The baseline data from the ReFlaP observational, prospective, multicentre and international study was used (NCT03119805). Cutoffs for PsAID12 were determined against disease activity scores, defining disease impact states (ie remission, low impact, moderate impact and high impact).

Spontaneously regressing mass-like soft tissue involvement in a child with chronic non-bacterial osteomyelitis: case-based review.

Chronic non-bacterial osteomyelitis (CNO) is an inflammatory bone disease, usually diagnosed in childhood. It is characterized by the presence of multifocal or unifocal osteolytic lesions that can cause bone pain and soft tissue swelling. CNO is known to have soft tissue involvement.

Conservative management of pediatric pineal cyst apoplexy: a case report and literature review.

A 5-month-old male patient presented with obstructive hydrocephalus caused by pineal cyst apoplexy. Ventriculoperitoneal shunt surgery was performed for hydrocephalus treatment. During follow-up, spontaneous shrinkage of the cyst was observed.

Basic Science and Pathogenesis.

Background: The Cognitive Function Index (CFI) is a validated test used to assess changes in self-perceived cognitive and functional status as reported by an individual and their study partner. Previous studies have demonstrated an inverse correlation between higher amyloid-beta (Aβ) burden and CFI, with certain CFI items exhibiting stronger associations than others. However, there is limited understanding of the association between declines in cognition and function, as assessed by CFI, and Tau levels measured by PET.

Basic Science and Pathogenesis.

Background: Huntington's disease (HD) is a progressive neurodegenerative disorder phenotypically manifested by motor, cognitive and psychiatric symptoms (Novak and Tabrizi, 2011). These patients are also characterized by vigilance abnormalities. This has been demonstrated by electrophysiological measures (Wiegand et al.

Basic Science and Pathogenesis.

Background: Astrocytes secrete neuromodulators, neurohormones, trophic factors, and synaptogenesis modulators. Trophic factors regulate various cellular processes including synaptic transmission. Astrocytes have critical roles in synaptic development and plasticity.

Basic Science and Pathogenesis.

Background: Parkinson's disease and Huntington's disease are both neurodegenerative conditions involving the basal ganglia area of the brain. Both conditions can cause symptoms that affect movement. Cognitive decline or dementia can also occur in both.

Anatomic Changes of Patients With Obstructive Sleep Apnea Syndrome at Different Stages.

Aim: In this study, it was aimed to determine the changes in the anatomic structures of individuals with obstructive sleep apnea syndrome (OSAS) classified according to the apnea-hypopnea index (AHI).

Materials And Methods: Individuals were divided into groups as group 1 (AHI=0, n=20), group 2 (AHI ˂5, n=20), group 3 (AHI=5-15, n=20), group 4 (AHI=16-30, n=20), group 5 (AHI ˃30, n=20). The individuals left lateral cervical vertebra radiographs were taken.

Clinical Manifestations.

Background: Valosin Containing Protein (VCP) mutations are responsible some genetic etiologies of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

Method: A 67-year-old, male patient, applied to the clinic due to behavioral changes and difficulty swallowing. According the patient history it was reported that his first complaint started 6 years ago (at the age of 61).

R(3780) Resonance Interpreted as the 1^{3}D_{1}-Wave Dominant State of Charmonium from Precise Measurements of the Cross Section of e^{+}e^{-}→Hadrons.

We report the precise measurements of the cross section of e^{+}e^{-}→hadrons at center-of-mass energies from 3.645 to 3.871 GeV.

Clinical Manifestations.

Background: Emerging technologies paves the way for the development of novel cognitive assessment approaches. Virtual reality (VR) has high ecological validity, increases participant engagement, and allows the assessment of functions that are challenging to evaluate with traditional methods. The present study aimed to validate a novel cognitive assessment tool and investigate the effects of demographical variables.

Exploring Rehabilitation Protocols for Primary Anterior Cruciate Ligament Repair: Insights from a Scoping Review.

Objectives: The primary repair of the anterior cruciate ligament (ACL) has re-emerged as a treatment for acute ruptures. While numerous studies have investigated rehabilitation after ACL reconstruction, few have focused on primary repair. We aimed to describe the rehabilitation protocols for primary ACL repair, and to identify knowledge gaps and differences between primary ACL repair and reconstruction.