373,422 results match your criteria: "Turkey; Koc University Research Centre for Translational Medicine[Affiliation]"

Background: This study aimed to examine the early clinical outcomes of AngioJet rheolytic thrombectomy (RT) in patients with acute bilateral iliofemoral deep vein thrombosis (IFDVT), with a specific focus on the incidence of post-thrombotic syndrome (PTS).

Methods: From March 2021 to August 2023, sixteen consecutive patients with acute bilateral IFDVT treated with AngioJet RT at our center were evaluated. Primary outcomes include patency of the target veins, development of PTS, recurrent DVT, and procedure related death.

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Background: Humidity between the toes and occlusion are risk factors and causes of recurrence for interdigital tinea pedis.

Objective: To determine the role of wearing "finger-socks" in addition to topical antifungal treatment in managing interdigital tinea pedis.

Methods: Among 54 patients with interdigital tinea pedis confirmed by direct microscopy, 31 in the study group were recommended to wear five-finger socks in addition to topical antifungal treatment for four weeks, while 23 in the control group received only topical antifungal treatment without sock recommendations.

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"Effectiveness and tolerability of intravenous fosfomycin in treating complicated urinary tract infections caused by Escherichia coli: A prospective cohort study from the FOSFO-MIC Project".

Clin Microbiol Infect

January 2025

Unidad de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena and Departamento de Medicina, Universidad de Sevilla/Instituto de Biomedicina de Sevilla/CSIC, Seville, Spain; CIBER de Enfermedades Infecciosas (CIBERINFEC). Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

Objectives: The FOSFO-MIC study assessed the clinical and microbiological effectiveness, and safety of intravenous fosfomycin in treating complicated urinary tract infections (cUTIs) caused by Escherichia coli, in comparison with other intravenous antimicrobials.

Methods: A prospective, multinational matched-cohorts study involving adults with community-acquired cUTIs and receiving targeted therapy with intravenous fosfomycin or other first-line drugs (beta-lactams or fluoroquinolones) was conducted from November 2019 to May 2023 in 10 centres from Spain, Italy, and Türkiye. Matching criteria included healthcare-relation, Charlson and Pitt scores.

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The widespread use of polyethylene terephthalate (PET) in food and beverage packaging raises concerns about its potential health effects, particularly when PET-derived nanoplastics (PET-NPs) are released into the environment. This study investigates the reproductive toxicity of PET-NPs in male mice. Mice were exposed to PET-NPs at doses of 0.

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Context: Although cranial distant effects occur in self-myofascial release interventions for lower-extremity muscles and fascia, the results of caudal distant effects are still unclear. The aim of this study was to examine the distant effects of myofascial release applied to the thoracolumbar fascia together with exercise training on balance, lower-extremity flexibility, and muscular endurance in healthy young adults.

Design: Single-blinded randomized control trial design.

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As our planet faces increasing environmental challenges, such as biotic pressures, abiotic stressors, and climate change, it is crucial to understand the complex mechanisms that underlie stress responses in crop plants. Over past few years, the integration of techniques of proteomics, transcriptomics, and genomics like LC-MS, IT-MS, MALDI-MS, DIGE, ESTs, SAGE, WGS, GWAS, GBS, 2D-PAGE, CRISPR-Cas, cDNA-AFLP, HLS, HRPF, MPSS, CAGE, MAS, IEF, MudPIT, SRM/MRM, SWATH-MS, ESI have significantly enhanced our ability to comprehend the molecular pathways and regulatory networks, involved in balancing the ecosystem/ecology stress adaptation. This review offers thorough synopsis of the current research on utilizing these multi-omics methods (including metabolomics, ionomics) for battling abiotic (salinity, temperature (chilling/freezing/cold/heat), flood (hypoxia), drought, heavy metals/loids), biotic (pathogens like fungi, bacteria, virus, pests, and insects (aphids, caterpillars, moths, mites, nematodes) and climate change stress (ozone, ultraviolet radiation, green house gases, carbon dioxide).

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Evaluation of relationship between the language development and parental attitudes in children with cochlear implant.

Int J Pediatr Otorhinolaryngol

January 2025

Department of Audiology, Faculty of Health Science, Istanbul Aydin University, Istanbul, Turkey. Electronic address:

Objective: The primary aim of this study was to examine the relationship between parental attitudes and language development in preschool children with cochlear implants. In addition, the study aimed to examine parental attitudes in relation to socio-demographic and cochlear implant related variables.

Methods: This study is based on the relational survey model.

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The clinical assessment of lung involvement in patients with Still's disease, results from the multicentre international AIDA Network Still's Disease Registry.

Rheumatology (Oxford)

January 2025

Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.

Objectives: To assess the lung involvement in patients with Still's disease, an inflammatory disease assessing both children and adults. To exploit possible associated factors for parenchymal lung involvement in these patients.

Methods: A multicentre observational study was arranged assessing consecutive patients with Still's disease characterized by the lung involvement among those included in the AIDA (AutoInflammatory Disease Alliance) Network Still's Disease Registry.

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Introduction: This study aims to investigate the presence of class 1, 2, and 3 integrons in Acinetobacter baumannii isolates, evaluate the relationship between integrons and antibiotic resistance and determine the clonal relationship between isolates by PFGE method.

Methodology: A total of 188 A. baumannii strains between February 2020 and March 2023 were included in the study.

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Introduction: Antimicrobial resistance remains a global threat with increasing morbidity and mortality rates. The aim of this study was to identify the antimicrobial resistance trends among ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) isolated from clinical samples at a Health Practice and Research Hospital over five years.

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Ongoing post-COVID-19 symptoms and complaints among healthcare professionals.

J Infect Dev Ctries

December 2024

Family Medicine, Merkezefendi District Health Directorate, Denizli, Turkey.

Introduction: Post-COVID-19 syndrome refers to the occurrence of symptoms lasting more than 4 weeks in individuals who have recovered from COVID-19. This study aims to investigate the post-COVID-19 symptoms in healthcare professionals.

Methodology: This descriptive study included 166 healthcare professionals who had tested positive for COVID-19 via PCR at least four weeks prior and subsequently presented to the Family Medicine Clinic at Pamukkale University Training and Research Hospital.

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Dry ice is one of the world's most in-demand commodities for cold-chain distribution of temperature-sensitive products. It offers an effective cooling solution without requiring mechanical refrigeration or specialized equipment. Dry ice is commonly produced as pellets and blocks.

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Objective: This study aims to explore how sociodemographic, psychological, and quality of life factors impact dual-task performance among elderly individuals in Iraq.

Methods: This cross-sectional study included 384 healthy community-dwelling participants aged 60 years and over, recruited from Najaf, Iraq. Data were collected using the Depression Anxiety Stress Scales-21 (DASS-21), Mindful Attention Awareness Scale (MAAS), and the World Health Organization Quality of Life Brief Form (WHOQOL-BREF).

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Regulatory effects of resveratrol on nitric oxide signaling in cardiovascular diseases.

Pharmacol Rep

January 2025

Center for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.

Cardiovascular illnesses are multifactorial disorders and represent the primary reasons for death worldwide, according to the World Health Organization. As a signaling molecule, nitric oxide (NO) is extremely permeable across cellular membranes owing to its unique molecular features, like its small molecular size, lipophilicity, and free radical properties. Some of the biological effects of NO are vasodilation, inhibition in the growth of vascular smooth muscle cells, and functional regulation of cardiac cells.

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High dose aflibercept treatment in naive neovascular age-related macular degeneration.

Int Ophthalmol

January 2025

Beyoglu Eye Training and Research Hospital, University of Health Sciences, Bereketzade Camii Sk. No:2 Beyoğlu, 34421, Istanbul, Turkey.

Background: To evaluate the efficacy and safety of intravitreal injections of 4 mg (high dose) of aflibercept in treatment-naive patients with neovascular AMD(nAMD) with treat and extend(TREX) dosing regimens, and to determine the frequency of injections.

Methods: In this interventional, retrospective study a total of 15 eyes of 14 patients (eight female and 9 male) with nAMD were included. All patients were examined and OCT imaging was performed at the time of initial presentation, on the day of each injection and at subsequent follow-up visits.

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The utilisation of implantable medical devices has become safer and more prevalent since the establishment of sterilisation methods and techniques a century ago. Nevertheless, device-associated infections remain a significant and growing concern, particularly in light of the continued rise in the number of medical device implantations. This underscores the imperative for the development of efficacious prevention and treatment strategies for device-associated infections, as well as further investigation into the design of innovative antibacterial surfaces for medical device applications.

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Background: Primary percutaneous coronary intervention (p-PCI) is pivotal in managing ST-segment elevation myocardial infarction (STEMI); however, it introduces potential risks, such as contrast-induced acute kidney injury (CI-AKI). This study aimed to investigate the relationship between pulse pressure (PP) and CI-AKI incidence in diabetic patients.

Methods: In this retrospective study conducted between 2021 and 2022, 590 diabetic STEMI patients undergoing p-PCI were categorized based on the presence of wide PP.

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Lithium has long been used as a cornerstone mood stabilizer in the treatment of bipolar disorder (BD). However, reliable biomarkers that can predict which patients will respond better to lithium are still lacking. This study aims to evaluate the potential of NR1D1 gene SNP; rs2071427 and actigraphic measurements in predicting lithium response.

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Pectin as a functional food ingredient in jelly marmalade.

Nat Prod Res

January 2025

Department of Maths and Science Education, Faculty of Education, Kırıkkale University, Yahşihan, Kırıkkale, Turkey.

This study uses a standardised protocol to explore prototype marmalade production using hawthorn fruit puree and sea buckthorn pectin. Hawthorn fruit puree exhibited a rich nutritional profile, prompting sea buckthorn pectin incorporation to enhance gelling capacity. Physicochemical analysis confirmed pectin's suitability.

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Background: To determine the effect of the health literacy levels of caregivers of individuals with T2DM on caregiving activities and supportive behaviours.

Methods: Cross sectional study. The sample for the study comprised of people who provided care for 442 individuals who were diagnosed with diabetes.

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Aim: The aim of this study is to determine women's perceptions of respectful maternity care, the effect of giving birth in a mother-friendly hospital on this perception and other factors affecting this perception.

Background: The philosophy of a mother-friendly hospital includes respectful maternity care. Few quantitative studies have been conducted in Turkey to assess the prevalence of respectful maternity care during childbirth and none have examined the difference between respectful maternity care in mother-friendly and nonmother-friendly hospitals.

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Aim: Professional knowledge and awareness of children begins to create at the age of 3-5, and the professional knowledge have acquired at this age was effective in their future career decision-making. This study aimed to develop the Children's Perceived Nursing Image Scale (CPNIS) and evaluate its psychometric properties.

Methods: The methodological study was carried out in a cross-sectional, descriptive, and correlational design.

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Rationale: The present study aimed to understand the experiences of intern nurses returning to clinical practice after a year-long distance education during the pandemic.

Methods: The study was conducted using the qualitative content analysis method. The participants were 32 intern nurses.

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